Stresses caused by ionizing radiation can also damage tissues and organs through the circulatory system. In this study, we aimed to determine the radioprotective effect of propolis, a natural and powerful antioxidant product, against oxidative liver damage caused by cranial irradiation. Thirty-two male albino Sprague–Dawley rats, divided into four groups, were designed as sham group, irradiation (IR) group, propolis plus IR, control group of propolis. Biochemical parameters were measured in liver tissue of rats. While Total enzymatic superoxide scavenging activity (TSSA) and non-enzymatic superoxide scavenging activity (NSSA), glutathione peroxidase (GSH-Px) activities of all groups were statistically significantly higher than rats receiving only-irradiation, Glutathione-S-transferase (GST) activity in the IR group was significantly lower than in the sham control group and IR + propolis group. Superoxide dismutase (SOD) activity in the IR group was found to be significantly higher than both the sham control group and the propolis control group, but lower than the IR + propolis group. Malondialdehyde level and xanthine oxidase activity were higher in the IR group than in the other groups. Compared to the sham control group, in the group treated with propolis, a significant elevation in antioxidant parameters, specifically TSSA, NSSA, SOD, and GST activities, was noted, with corresponding increases of 32.3%, 23.2%, 47.6%, and 22.6%, respectively. Our findings show that propolis can be a radioprotective agent against ionized radiation damage by increasing antioxidant activity and reducing oxidant stress in liver tissue.

Acute appendicitis is an inflammation of the appendix caused by various factors and is the most common cause of acute abdominal pain presenting to the emergency department. Open appendectomy was first described by McBurney in 1894 using an incision ...

Amaç: Bu araştırma, bir devlet hastanesinde çalışan hemşirelerin basınç yaralarını önlemeye yönelik tutumlarının incelenmesi amacıyla yapılmıştır. Gereç ve Yöntem: Araştırmanın evrenini, Doğu Anadolu Bölgesindeki bir ilin merkezinde bulunan bir kamu hastanesinde çalışan toplam 246 hemşire oluşturmuştur. Araştırmada evrenin tamamına ulaşılmaya çalışılmış ve araştırmaya gönüllü olarak katılan 241 kişiden veri toplanmıştır. Verilerin toplanmasında araştırmacılar tarafından oluşturulan 31 soruluk “Anket Formu” kullanılmıştır. Literatürden destek alınarak oluşturulan anketteki veriler; hemşirelerin basınç ülserlerini önlemeye yönelik tutumlarını incelemek amacıyla 18 sorudan oluşan Hemşire Tanıtım Formu ve 13 sorudan oluşan Basınç Ülserlerini Önlemeye Yönelik Tutum Ölçeği kullanılarak toplanmıştır. Bulgular: Lisans mezunu hemşirelerin basınç ülserlerinin etkisine yönelik, basınç ülserlerini önlemede kişisel sorumluluğa yönelik ve basınç ülserlerini önlemenin etkinliğine yönelik tutumlarının daha yüksek olduğu saptandı. Lise mezunlarının ise basınç ülserlerini önlemek için bireysel yeterliliğe yönelik tutumlarının daha yüksek olduğu ve gruplar arasındaki farkın anlamlı olduğu saptandı (p<0,05). Sonuç: Bu çalışma sonucunda, hemşirelerin basınç ülserini önlemeye yönelik tutum düzeylerinde eksiklikler mevcuttur. Bu bağlamda; her kurum standartlara ve yeniliklere uygun basınç ülseri bakım protokolleri belirlemeli, klinik uygulama rehberleri geliştirmeli ve uygunluğunun denetlemesini sağlamalıdır. Objective: This study was conducted in order to investigate the attitudes of nurses working in a state hospital towards prevention of pressure ulcers. Material and Methods: The population of the present study consisted of a total of 246 nurses, who were working in a public hospital located in a city center in Eastern Anatolia Region. The study, it was attempted to reach the whole population, and the data were collected from 241 nurses who voluntarily participated in the study. A “Questionnaire” with 31 questions, which was prepared by the researchers, was used to collect the data. The data on the questionnaire prepared by the support of literature were collected using Nurse Information Form with 18 questions to investigate attitudes of nurses towards prevention of pressure ulcers as well as Attitude Towards Pressure Ulcer Prevention Instrument consisting of 13 questions. Results: The nurses with high school degree were determined to have higher attitudes towards the effect of pressure ulcers, towards the personal responsibility to prevent pressure ulcers, and towards the effectiveness of prevention of pressure ulcer. Attitudes of the nurses with high school degree towards personal sufficiency to prevent pressure ulcers were higher and the difference between the groups was significant (p<0.05). Conclusion: The present study revealed that attitude levels of nurses towards pressure ulcer prevention had some deficiencies. Within this context, each institution should determine pressure ulcer care protocols appropriate to standards and innovations, develop clinical practice guides, and ensure supervision of their convenience.

In the literature, a variety of techniques are recommended for intraoperative biliary tract imaging. The objective of this study was to develop a more cost-effective and widely applicable technique that could serve as an alternative to existing imaging techniques by taking advantage of the chemiluminescence effect of luminol. An experimental study using rabbits was designed. The rabbits in the control group received isotonic solution, while the other groups were administered various concentrations of luminol chemical solutions with catalyst and activator chemicals. Biliary tract imaging was conducted using chemiluminescence in the biliary tract during luminol injection, and the resulting images were recorded. The intraoperative imaging of bile ducts in rabbits was successfully achieved through the utilization of the chemiluminescence effect of luminol. The statistical analysis of the laboratory results and histopathological examination revealed no statistically significant difference between the groups used with varying concentrations of luminol and other chemicals and the control group. The methodology employed in this study is cost-effective, readily accessible, and straightforward to implement. In light of these findings, we posit that this technique may serve as a potential alternative to existing methods in the future.