A novel experimental setup for the generation of arbitrary vector beams is proposed. The system major includes two reflective liquid crystal spatial light modulators (RLC-SLM) and a polarizing beam splitting prism. Moreover, this method is not limited by the wavelength of light wave and the pixel size of SLM. Theoretical analysis shows that when Gaussian beam or a plane beam is illuminated on a computer-generated hologram (CGH) specially designed in this work, the complex amplitudes of the vector field’s two orthogonal polarization components may be changed by modifying the encoding parameters, resulting in a vector beam with arbitrary complex amplitude and polarization in the output field. The experimental results also show that the two independent coding channels of the device have good polarization-selective imaging ability, which greatly improves the flexibility of generating arbitrary vector beams.