Luiz Miguel de Mendonça Soares Santiago

Prof. Luiz Miguel de Mendonça Soares Santiago

Faculdade de Medicina da Universidade de Coimbra, Coimbra, Portugal
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Research Focus & Metrics

Academic Career Length

28Years (1999-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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25 September 2015 in BMJ Open
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Filipe PrazeresFilipe Prazeres
Filipe Prazeres
LSLuiz Miguel de Mendonça Soares Santiago
Luiz Miguel de Mendonça Soares Santiago
Objectives To determine the prevalence of multimorbidity in the adult population attending primary care in Portugal, to identify associated sociodemographic factors, and to reveal combinations of chronic health problems. Design Cross-sectional, analytical study. Setting Primary Care Centres in mainland Portugal across the five Portuguese Healthcare Administrative Regions. Participants 1279 women and 714 men agreed to participate. The mean age was 56.3 years (59.0 years for men; 54.8 years for women). The most frequent marital status was married/cohabiting (69.5%). The most predominant living arrangement was living as a couple (57.2%). A considerable proportion consisted of pensioners/retirees (41.5%) and adults with a low educational level (48.7%). Sufficient monthly income was reported in 54.4% of the cases. Primary outcome measures For each patient, multimorbidity was measured either by the presence of ≥2 or ≥3 chronic health problems, from a list of 147 chronic health problems. Clinical data were collected using the general practitioner's knowledge of the patient's history, patient's self-report and medical records. Cluster analyses were performed to reveal distinct patterns of multimorbidity. Secondary outcome measures Patient social and demographic data (sex, age, residence area, current marital status, number of years of formal education, living arrangements, professional status and self-perceived economic status). Logistic regression analyses were performed to determine the association between sociodemographic factors and multimorbidity. Results Multimorbidity (2 or more chronic health problems) was present in 72.7%. When a cut-off of three or more was used, an expressive percentage of multimorbidity (57.2%) remained present. The likelihood of having multimorbidity increased significantly with age. Pensioners/retirees and adults with low levels of education were significantly more likely to suffer from multimorbidity. Cardiometabolic and mental disorders were the most common chronic health problems. Six multimorbidity clusters have been identified. Conclusions Multimorbidity was found to be a common occurrence in the Portuguese primary care users. Future primary healthcare policies should take multimorbidity into consideration.

11 November 2016 in Health and Quality of Life Outcomes
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Filipe PrazeresFilipe Prazeres
Filipe Prazeres
LSLuiz Miguel de Mendonça Soares Santiago
Luiz Miguel de Mendonça Soares Santiago
Multimorbidity has a high prevalence in the primary care context and it is frequently associated with worse health-related quality of life (HRQoL). Few studies evaluated the variables that could have a potential effect on HRQoL of primary care patients with multimorbidity. The purpose of this study, the first of its kind ever undertaken in Portugal, is to analyse the relationship between multimorbidity, health-related quality of life, perceived family support and unmet health needs in adult patients attending primary care. Multicentre, cross-sectional survey conducted among primary care patients with multimorbidity. It included 521 participants (64.1 % females) who met the inclusion criteria. HRQoL was evaluated using the Portuguese Short Form-12 Health Status Questionnaire. The Portuguese Family APGAR was used to measure the perceived family support. A patients’ unmet health needs questionnaire was used. The unmet needs for medical, surgical and dental care; prescription medications; mental healthcare or counselling; and eyeglasses or other technical aid was assessed. Descriptive and multivariate analyses were performed. The sample had an overall average of 4.5 chronic health problems. Increased multimorbidity levels were linked to worse health-related quality of life, particularly the physical health. Some variables were confirmed as playing a role on health-related quality of life. Male patients with high monthly incomes and highly functional families had better physical and mental health. High levels of education and the presence of asthma were also associated with better physical health. Contrariwise, elderly patients with high levels of multimorbidity and with osteoarthritis had lower physical health. The majority of the patients did not have unmet health needs. When health needs were stated they were mostly for generalist medical care, dental care, and eyeglasses/other technical aid. Financial insufficiency was the primary reason for not fulfilling their health needs. To improve the quality of life of multimorbid patients, within primary care practices and health delivery systems, one should take into special account the sex of the patient, the perceived family support and the self-perceived economic status because of their relationship with both physical and mental health. Limitations and recommendations are discussed.

1 September 2019 in Patient Preference and Adherence
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PSPedro Simões
Pedro Simões
LSLuiz Miguel de Mendonça Soares Santiago
Luiz Miguel de Mendonça Soares Santiago
KMKatia Maurício
Katia Maurício
José Augusto Rodrigues SimõesJosé Augusto Rodrigues Simões
José Augusto Rodrigues Simões
Background: In potentially inappropriate medications harm potentially outweighs benefits. Even appropriately prescribed medications may become inappropriate. They can lead to a high risk of adverse drug reactions, morbidity and mortality. The aim of this study was to determine the prevalence of potentially inappropriate medication in the older adult population attending primary care in Portugal and to identify associated sociodemographic and clinical factors. Methods: We conducted a cross-sectional, analytical study in primary care centres from the five Portuguese healthcare administrative regions and the two autonomous regions. We used a random sample of 757 older patients provided by the information department of the ministry of health (SPMS) and family doctors from the autonomous regions. Data collection occurred March 2018 and we studied sociodemographic characteristics, clinical profile and medication. We used 2015 Beers Criteria to assess potentially inappropriate medications. Logistic regression analyses were performed to determine associations between potentially inappropriate medications’ prescriptions and other variables. Results: Potentially inappropriate medication was present in 68.6% and 46.1% of the sample had two or more. The likelihood of having potentially inappropriate medication increased significantly with being female (OR=1.56 [1.05 to 2.31]), number of chronic health problems (OR=1.06 [1.01 to 1.13]), number of pharmacological subclasses (OR=1.40 [1.30 to 1.51]) and number of prescribers (OR=1.34 [1.09 to 1.65]). Proton-pump inhibitors, nonsteroidal anti-inflammatory drugs and benzodiazepines were the most commonly found ones. Conclusion: Potentially inappropriate medication in older adults was found to be a common occurrence in Portugal. It is important that doctors are aware of this problem, namely in the primary care setting due to the longitudinal care.

26 October 2016 in The Physician and Sportsmedicine
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Journal Article
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ACAntonio Miguel Cruz-Ferreira
Antonio Miguel Cruz-Ferreira
ECEduardo Cruz-Ferreira
Eduardo Cruz-Ferreira
LSLuiz Miguel de Mendonça Soares Santiago
Luiz Miguel de Mendonça Soares Santiago
LTLuis Taborda-Barata
Luis Taborda-Barata
Objectives: In 2016 the Rugby Union variant of sevens will enter the official Olympic Programme. Until now, most of injury surveillance studies in Rugby Union focus on elite 15-a-side cohorts, with reported injury incidence rates reaching 96 per 1000 player-match-hours, and mean severity set at 20 days. Sparse data is available regarding rugby sevens. The aim of this study was to systematically review available data regarding the epidemiology of injuries in senior male rugby sevens. Methods: Electronic databases (Pubmed, Google Scholar, SCOPUS, Scielo and IndexRMP) were searched in September 2015, complemented by manual searches of bibliographies and relevant “grey literature”. Results: Seven prospective cohort original articles addressing injuries in senior male rugby sevens players were included in this review. Overall injury incidence rates in elite rugby sevens tournaments ranged 101.5 to 119.8 per 1000 player-match-hours. Mean severity was greater than 34.1 days. Lower limb and joint/ligament injuries were the most frequent in elite players. The only study on amateur players revealed a lower injury incidence rate (74.7 per 1000 player-match-hours), and a higher proportion of muscle/tendon (37.5 %) injuries. Conclusion: Injury incidence rates in rugby sevens are higher than those reported for the 15-a-side variant, at the same level of competition. Injuries are also more severe, resulting in longer absence periods. This might result from the fact that rugby sevens is played with greater speed, leading to an increase in energy transfers during tackles, more running and turning manoeuvers, that can possibly cause more severe injuries.

1 February 2018 in Revista da Associação Médica Brasileira
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IRInês Rosendo
Inês Rosendo
LSLuiz Miguel de Mendonça Soares Santiago
Luiz Miguel de Mendonça Soares Santiago
MMMargarida Marques
Margarida Marques
Summary Introduction: Diabetes therapeutic education and information by leaflets is important. This study aimed to understand the effectiveness of written information to diabetic patients, after six months, in the control of diabetes and medication adherence. Method: Non-pharmacological clinical trial. Randomized sample of diabetic patients of 65 volunteer doctors, distributed among the five health regions in Portugal. At the first appointment, patients were randomized in four groups (three intervention with validated leaflets and one control), leaflet reading being reinforced at the follow-up appointments in a 6-months period. Variables collected: HbA1c, home blood glucose, weight, waist circumference, blood pressure, cigarettes smoked, physical activity level, adherence to medication, medication, height, diabetes progression, age, sex and educational background. Descriptive and inferential statistics. Results: From the 709 patients recruited, 702 were studied in this 6-months period with no statistical differences in the baseline variables studied. After six months of intervention, the adherence to medication improved in the leaflet group (p=0.034). This was noticed in those under 65 years of age (p=0.027), with diabetes for ≤ 5 years (p=0.010), with educational background up to 4 years (p=0.030) and 9 years (p=0.006) and with HbA1c ≥ 7% at the beginning of the study. Conclusion: Interventions with leaflets handed in primary healthcare to people with diabetes type 2 can bring benefits in what concerns adherence to therapeutics, namely in younger people with a less studies.

1 June 2020 in Acta Medica Portuguesa
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TDTomás Dinis
Tomás Dinis
LSLuiz Miguel de Mendonça Soares Santiago
Luiz Miguel de Mendonça Soares Santiago
IRInês Rosendo
Inês Rosendo
João MarôcoJoão Marôco
João Marôco
Introdução: A participação em atividades extracurriculares reduz a importância atribuída a alguns motivos para o perfeccionismo que influenciam a prevalência de burnout nos estudantes de medicina. Este estudo visou investigar de que forma esta relação se processa e de que fatores depende, de forma a pensar estratégias direcionadas a estes potenciais alvos de atuação.Material e Métodos: Elaborou-se um questionário capaz de avaliar a prática de atividades extracurriculares que incluiu um inquérito dos motivos para o perfeccionismo e parte do Copenhagen Burnout Inventory adapted for students. À sua aplicação, via online, aos estudantes do Mestrado Integrado em Medicina da Faculdade de Medicina da Universidade de Coimbra, seguiu-se a análise estatística e inferencial dos dados obtidos.Resultados: Numa amostra de 360 alunos, 40% pontuaram elevados níveis de burnout pessoal e 28,1% de burnout relacionado com os estudos, tendo 22,2% obtido elevados níveis nas duas componentes. Alunos que praticavam atividades extracurriculares estiveram menos frequentemente associados a altos valores de burnout pessoal e relacionado com os estudos, simultaneamente (p = 0,013). O tipo de atividade extracurricular escolhido não mostrou relação com a prevalência de burnout.Discussão: Apenas 53,9% dos alunos participam numa atividade extracurricular, fator associado a uma menor prevalência de burnout, especialmente nos alunos que a realizam várias vezes por semana. A escolha de um tipo de atividade em detrimento de outro não parece influenciar a prevalência desta síndrome, estando todos associados a benefícios em diferentes domínios.Conclusão: Verificou-se menor prevalência de burnout em estudantes que praticavam atividades extracurriculares. Será necessária a realização de estudos que nesta relação permitam inferir causalidade, de forma a formular soluções efetivas e específicas do contexto do curso médico.