To describe the development of the post-myopic laser vision correction (LVC) version of the PEARL-DGS intraocular lens (IOL) calculation formula and to evaluate its outcomes on an independent test set. Retrospective, single-center case series. A modified lens position prediction algorithm was designed along with methods to predict the posterior corneal curvature radius and correct the corneal power measurement error. A different set of previously operated eyes that underwent LVC was used to evaluate the prediction precision of the post-LVC formula. Post-LVC PEARL-DGS formula significantly reduced mean absolute error of prediction in comparison to Haigis-L, Shammas, and American Society of Cataract and Refractive Surgery (ASCRS) average formulas (P < .001). It exhibited similar postoperative refractive precision as the Barrett True-K No History formula (P = .61). The post-LVC formula development process described in this article performed as well as the state-of-the-art post-LVC formula on the present test set. Further studies are required to assess its efficacy in other independent sets.

Purpose - This study aims to describe a novel technique for preparing Corneal Allogenic Ring Segments (CAIRS) using femtosecond laser (FSL) technology. Setting - Hospital Foundation Adolphe de Rothschild- Noémie de Rothschild institute. Design - Pre-clinical study conducted on human corneal grafts. Methods - The corneal grafts were mounted on an artificial chamber pressurized (ACP) with preset constant pressure, and the femtosecond laser was used to create a circular annulus with specific dimensions. The resulting CAIRS were analyzed for their thickness and width after air drying. Results: A total of 25 CAIRS were prepared using the femtosecond laser. The mean width and thickness of the CAIRS were 803 ± 77 μm and 83 ± 16 μm, respectively. Statistical analysis revealed no significant differences in width among the various quadrants of each CAIRS or between different CAIRS. Significantly thicker CAIRS were obtained with higher ACP pressure. Conclusion: The technique of CAIRS preparation using femtosecond laser technology and controlled artificial anterior chamber (AAC) pressure demonstrated reproducibility and precision. This approach holds the potential for customizing and personalizing CAIRS based on individual corneal characteristics.

The present study is a retrospective, monocentric case series that aims to compare the second-eye IOL power calculation precision using the back-calculated lens position (LP) as a lens position predictor versus using a predetermined correction factor (CF) for thin- and thick-lens IOL calculation formulas. A set of 878 eyes from 439 patients implanted with Finevision IOLs (BVI PhysIOL, Liège, Belgium) with both operated eyes was used as a training set to create Haigis-LP and PEARL-LP formulas, using the back-calculated lens position of the contralateral eye as an effective lens position (ELP) predictor. Haigis-CF, Barrett-CF, and PEARL-CF formulas using an optimized correction factor based on the prediction error of the first eye were also designed. A different set of 1500 eyes from 1500 patients operated in the same center was used to compare the basal and enhanced formula performances. The IOL power calculation for the second eye was significantly enhanced by adapting the formulas using the back-calculated ELP of the first eye or by using a correction factor based on the prediction error of the first eye, the latter giving slightly higher precision. A decrease in the mean absolute error of 0.043D was observed between the basal PEARL and the PEARL-CF formula (p < 0.001). The optimal correction factor was close to 60% of the first-eye prediction error for every formula. A fixed correction factor of 60% of the postoperative refractive error of the first operated eye improves the second-eye refractive outcome better than the methods based on the first eye’s effective lens position back-calculation. A significant interocular biometric dissimilarity precludes the enhancement of the second-eye IOL power calculation according to the first-eye results.

Purpose: EndoArt, a synthetic endothelial substitute for corneal edema, often requires multiple rebubbling procedures because of high detachment rates. This study reports 2 cases of spontaneous EndoArt reattachment, suggesting a potential alternative management approach. Methods: Two patients with endothelial dysfunction underwent EndoArt implantation. Both experienced partial detachment postoperatively. Although rebubbling was considered, a conservative approach was taken, leading to spontaneous reattachment. Serial anterior segment optical coherence tomography (AS-OCT) monitored graft adherence and corneal thickness. Results: Spontaneous reattachment occurred within 2 to 6 weeks, accompanied by progressive corneal thinning and clarity improvement. No further intervention was required, and reattachment remained stable for 6 to 8 months. These cases challenge the notion that all EndoArt detachments necessitate immediate rebubbling. Conclusions: This is the first report of spontaneous EndoArt reattachment. Although rebubbling remains standard practice, observation may be a viable option in select cases, reducing the need for additional procedures. Further studies are needed to refine management strategies and improve outcomes.