Maria-Emilia Cerghedean-Florea

Dr. Maria-Emilia Cerghedean-Florea

Lucian Blaga University of Sibiu, Sibiu, Romania
orcid

Research Focus & Metrics

Academic Career Length

4Years (2023-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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26 April 2023 in Diagnostics
Verified
Journal Article
Open access
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CTCosmin-Adrian Teodoru
Cosmin-Adrian Teodoru
CTCorina Tudor
Corina Tudor
Maria-Emilia Cerghedean-FloreaMaria-Emilia Cerghedean-Florea
Maria-Emilia Cerghedean-Florea
HDHoratiu Dura
Horatiu Dura
CTCiprian Tanasescu
Ciprian Tanasescu
Horia Tudor StancaHoria Tudor Stanca
Horia Tudor Stanca
HELLP syndrome is a pregnancy complication, putting at risk the life of mother and child, characterized by high blood pressure, elevated liver enzymes and low platelets. Serous retinal detachment is a rare complication of pregnancy and may be associated with HELLP syndrome. One of the most common symptoms is a decrease in visual acuity. A rare case of bilateral exudative retinal detachment associated with HELLP syndrome is described in a 38-year-old woman a few hours after delivery. Optical coherence tomography (OCT) showed an amount of subretinal fluid and macular edema. Use of systemic corticosteroids and careful management of blood pressure led to early resolution of subretinal fluid and a good recovery of vision. Her final best corrected visual acuity was 1 (decimal notation) in both eyes at 2 weeks after delivery. These types of cases are rarely reported and highlight the importance of increasing awareness of this pathology among ophthalmologists.

18 January 2023 in Reports
Verified
Journal Article
Open access
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CTCosmin-Adrian Teodoru
Cosmin-Adrian Teodoru
Maria-Emilia Cerghedean-FloreaMaria-Emilia Cerghedean-Florea
Maria-Emilia Cerghedean-Florea
CTCiprian Tanasescu
Ciprian Tanasescu
HDHoratiu Dura
Horatiu Dura
SFSorin Radu Fleaca
Sorin Radu Fleaca
MMMihaela Laura Vica Matei
Mihaela Laura Vica Matei
Background: The aim of this study was to highlight the structural changes in patients with cataract following surgery and the repercussions on the anterior pole. Methods: A total of 83 patients diagnosed with cataract who underwent uneventful phacoemulsification was included. Every patient was examined one week prior to and two weeks after the surgery. Pre- and postoperative assessment included examination of the anterior and posterior segment, keratometry, and optical biometry. Results: The pre- vs. postoperative axial length (AL) mean difference was 0.07 ± 0.18 mm (p < 0.001).The mean difference of the postoperative anterior chamber depth (ACD) vs. preoperative ACD values (1.11 ± 0.50 mm) was also statistically significant (p < 0.001). The linear regression function postoperative central corneal thickness (CCT) = 0.9004 × (preoperative CCT) + 0.0668, where it characterized a reduced positive correlation (R2) of 68.89% between the postoperative CCT and preoperative CCT. The mean pre-/post-operative differences in the K1 values were 0.08 ± 0.38 D, with a statistically significant difference between the two datasets (p = 0.0152). The mean pre/postoperative difference in the K2 values was 0.002 ± 0.58 D (p = 0.4854). Conclusions: ACD deepened significantly postoperatively. Regarding AL, there was a decrease after surgery, and a very good positive correlation between the post and preoperative values. The CCT values decreased with age. The 2.2-mm corneal incision during cataract surgery resulted in a relatively small postoperative residual astigmatism.

28 April 2023 in Diagnostics
Verified
Journal Article
Open access
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CTCosmin-Adrian Teodoru
Cosmin-Adrian Teodoru
Mihai Dan RomanMihai Dan Roman
Mihai Dan Roman
AHAdrian Gheorghe Hasegan
Adrian Gheorghe Hasegan
CMClaudiu Matei
Claudiu Matei
CMCosmin Ioan Mohor
Cosmin Ioan Mohor
HDHoratiu Dura
Horatiu Dura
Intraocular foreign body injuries (IOFB) can lead to a number of intraocular pathologies; the visual results depend on the mechanism of the injury, the type of foreign body and the subsequent complications. The presence of intraocular cilia (eye lashes) following penetrating injury or surgical intervention is uncommon. In the present paper, we present a case of a 58-year-old woman with a history of eye trauma and a perforated corneal wound in the left eye that occurred 50 years ago. On the ophthalmological exam we noticed in the anterior chamber a straight linear extension, resembling cilia, extending behind the iris. The patient reports that it appeared during COVID-19 infection, after repeated episodes of coughing. After a follow-up period, we decided to remove the eyelash; 24 h after surgery, the patient complained of severe eye pain. Intraocular pressure (IOP) in LE was 54 mmHg. The slit-lamp examination showed perikeratic congestion, corneal edema and mydriasis. Eye hypotensive treatment was started immediately and the patient’s general condition slightly improved. Intraocular cilia can be tolerated for many years without causing any ocular reaction. The decision for surgical intervention must be taken according to the individual needs of the patient and his ocular characteristics with careful pre- and post-operative follow up.

18 February 2023 in Diagnostics
Verified
Journal Article
Open access
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CTCosmin-Adrian Teodoru
Cosmin-Adrian Teodoru
Mihai Dan RomanMihai Dan Roman
Mihai Dan Roman
HDHoratiu Dura
Horatiu Dura
Maria-Emilia Cerghedean-FloreaMaria-Emilia Cerghedean-Florea
Maria-Emilia Cerghedean-Florea
We report a case of orbital metastasis of infiltrative breast carcinoma in a 65-year-old man. The patient was diagnosed with stage four breast cancer one year before, for which a mastectomy was performed. He refused postoperative radiotherapy and chemotherapy at that time. He had a history of lung, liver, and mediastinal metastases. At admission, he presented with blurred vision, diplopia, ocular pain, and mild swelling of the upper lid of the left eye (LE). Computed tomography (CT) of the brain and orbit revealed a front-ethmoidal tissue mass with left orbital and frontal intracranial extension. Ophthalmologic examination revealed exophthalmos on the LE with a downward and outward deviation of the eyeball, proptosis, and intraocular pressure (IOP) of 40 mmHg. The patient’s treatment started with topical maximal anti-glaucomatous drops and radiotherapy sessions. After three weeks of follow-up, there was a gradual improvement of local symptoms and signs and a normal IOP.

7 February 2026 in Journal of Clinical Medicine
Verified
Journal Article
Open access
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BIBeuran David Ionuț
Beuran David Ionuț
IBIoana Ruxandra Boca
Ioana Ruxandra Boca
CCCătălin Cornăcel
Cătălin Cornăcel
CTCalin Petru Tataru
Calin Petru Tataru
CTCatalina-Ioana Tataru
Catalina-Ioana Tataru
CTCosmin-Adrian Teodoru
Cosmin-Adrian Teodoru
Background/Objectives: Macular Telangiectasia Type 2 (MacTel type 2) is a rare, progressive retinal disease that can lead to central vision loss. Optical coherence tomography (OCT) plays a crucial role in the early diagnosis, monitoring, and prognostic assessment of this condition. This narrative review aims to summarize the clinical features, OCT findings, and current management strategies for MacTel type 2. Methods: A literature search of PubMed, MEDLINE, and Google Scholar was performed for articles published from October 1993 to September 2025 using keywords related to MacTel type 2, OCT, clinical features, and treatment. All relevant clinical studies, including observational studies, clinical trials, and case series, were considered. The literature was screened independently by two authors, and a total of 69 articles were included. Results: Characteristic OCT findings include foveal cavitation, hyperreflective middle retinal layers, inner and outer retinal cavities, ellipsoid zone disruption, and retinal pigment clumps. Central macular thickness is consistently reduced, and structural biomarkers identified on OCT correlate with visual acuity decline. Treatment strategies vary by disease stage: non-proliferative MacTel type 2 currently has no universally effective therapy, although neuroprotective interventions such as ciliary neurotrophic factor (CNTF) show promising results. Proliferative MacTel type 2 is primarily managed with anti-vascular endothelial growth factor therapy (anti-VEGF), demonstrating functional and anatomical improvements. Conclusions: OCT provides essential structural evaluation for monitoring MacTel type 2, while treatment approaches remain stage-dependent. Emerging therapies, including CNTF implants and novel anti-VEGF agents, hold potential for improving outcomes.

9 March 2023 in Diagnostics
Verified
Journal Article
Open access
PDF file
CTCosmin-Adrian Teodoru
Cosmin-Adrian Teodoru
Mihnea MunteanuMihnea Munteanu
Mihnea Munteanu
NMNadina Mercea
Nadina Mercea
AMAlina Moatar
Alina Moatar
Horia Tudor StancaHoria Tudor Stanca
Horia Tudor Stanca
Maria-Emilia Cerghedean-FloreaMaria-Emilia Cerghedean-Florea
Maria-Emilia Cerghedean-Florea
Superior ophthalmic vein thrombosis (SOVT) is a rare clinical entity that may be associated with hypercoagulability status. We present a case of a 77-year-old woman who presented to the emergency department complaining of eye ptosis, chemosis and conjunctival congestion in the right eye (RE). The ophthalmological examination revealed best-corrected visual acuity (BCVA) was 0.5 for the right eye (RE) 0.5 and 0.06 for the left eye (LE). Intraocular pressure (IOP) was 25 mmHg in RE and 14 mmHg in LE. Non-contrast computed tomography (CT) of the brain and orbits revealed a hyperreflectivity at the level of the right ophthalmic vein and inferior rectus muscle hypertrophy. An extensive hypercoagulable panel was completed and we found a positive result for Factor V Leiden (heterozygous mutation) and methyl-enetetrahydrofolate reductase (MTHFR-C677T homozygous mutations). Systemic steroidal anti-inflammatory and anticoagulant treatments were started immediately. Gradual resolution of symptoms was noted during the hospitalization, and BCVA in her RE was established at 0.7 at the 10-week follow-up.