Çiğdem Uysal Pala

Dr. Çiğdem Uysal Pala

orcid

Research Focus & Metrics

Academic Career Length

15Years (2012-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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26 December 2022 in Antioxidants
Verified
Journal Article
Open access
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HAHuseyin Ayvaz
Huseyin Ayvaz
TCTurgut CABAROGLU
Turgut CABAROGLU
AAAsiye Akyildiz
Asiye Akyildiz
ÇPÇiğdem Uysal Pala
Çiğdem Uysal Pala
RTRiza Temizkan
Riza Temizkan
Diaconeasa ZoritaDiaconeasa Zorita
Diaconeasa Zorita
In this work, various concepts and features of anthocyanins have been comprehensively reviewed, taking the benefits of the scientific publications released mainly within the last five years. Within the paper, common topics such as anthocyanin chemistry and occurrence, including the biosynthesis of anthocyanins emphasizing the anthocyanin formation pathway, anthocyanin chemistry, and factors influencing the anthocyanins’ stability, are covered in detail. By evaluating the recent in vitro and human experimental studies on the absorption and bioavailability of anthocyanins present in typical food and beverages, this review elucidates the significant variations in biokinetic parameters based on the model, anthocyanin source, and dose, allowing us to make basic assumptions about their bioavailability. Additionally, special attention is paid to other topics, such as the therapeutic effects of anthocyanins. Reviewing the recent in vitro, in vivo, and epidemiological studies on the therapeutic potential of anthocyanins against various diseases permits a demonstration of the promising efficacy of different anthocyanin sources at various levels, including the neuroprotective, cardioprotective, antidiabetic, antiobesity, and anticancer effects. Additionally, the studies on using plant-based anthocyanins as coloring food mediums are extensively investigated in this paper, revealing the successful use of anthocyanins in coloring various products, such as dietary and bakery products, mixes, juices, candies, beverages, ice cream, and jams. Lastly, the successful application of anthocyanins as prebiotic ingredients, the innovation potential of anthocyanins in industry, and sustainable sources of anthocyanins, including a quantitative research literature and database analysis, is performed.

24 February 2012 in Food and Bioprocess Technology
Verified
Journal Article
Closed access
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ÇPÇiğdem Uysal Pala
Çiğdem Uysal Pala
ATAyşegül Kırca Toklucu
Ayşegül Kırca Toklucu

6 August 2018 in Journal of Food Measurement and Characterization
Verified
Journal Article
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ACAygül Can
Aygül Can
HAHüseyin Ayvaz
Hüseyin Ayvaz
ÇPÇiğdem Uysal Pala
Çiğdem Uysal Pala
NCNicola Condelli
Nicola Condelli
FGFernanda Galgano
Fernanda Galgano
Roberta TolveRoberta Tolve
Roberta Tolve

1 April 2018 in LWT
Verified
Journal Article
Closed access
SASerpil Aday
Serpil Aday
ÇPÇiğdem Uysal Pala
Çiğdem Uysal Pala
BÇBelgizar Ayana Çam
Belgizar Ayana Çam
SBSami Bulut
Sami Bulut

30 October 2022 in European Food Research and Technology
Verified
Journal Article
Closed access
PDF file
HAHuseyin Ayvaz
Huseyin Ayvaz
RTRiza Temizkan
Riza Temizkan
AMAhmed Menevseoglu
Ahmed Menevseoglu
MDMuhammed Ali Dogan
Muhammed Ali Dogan
BNBurak Alptug Nazlim
Burak Alptug Nazlim
ÇPÇiğdem Uysal Pala
Çiğdem Uysal Pala

1 July 2016 in SpringerPlus
Verified
Journal Article
Open access
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TŞTuncer Şimşek
Tuncer Şimşek
UAUğur Altınışık
Uğur Altınışık
İEİsmail Erşan
İsmail Erşan
HŞHasan Şahin
Hasan Şahin
BABetül Altınışık
Betül Altınışık
ÇPÇiğdem Uysal Pala
Çiğdem Uysal Pala
Oleuropein is known to have anti-oxidant and anti-inflammatory effects. An important aim of anesthetic management in ocular surgery is to keep the intraocular pressure under control. Studies have researched a variety of prophylactic materials used to prevent increases in intraocular pressure. We aimed to research the effects of oleuropein on intraocular pressure (IOP) during general anaesthesia. Fourteen New Zealand rabbits were randomly divided into two groups of seven. The rabbits in Group O were given olive leaf extract (OLE) equivalent to a daily dose of 20 mg/kg oleuropein for 15 days. HPLC method used for oleuropein standardization. For anaesthesia induction 1 mg/kg rocuronium was given and after muscle relaxation all animals had a V-gel Rabbit inserted. Anesthetic maintenance was provided by 1 MAC isoflurane. Twenty minutes after rabbits were given 10 mg/kg ketamine, basal IOP values were measured. After the V-gel rabbit was inserted, in the 5th, 10th, 20th, 25th and 30th minutes measurements were repeated. IOP data variation of OLE group was compared with control group and the measured levels were lower in Group O during the anaesthesia. IOP was 33.8 ± 4 mmHg in Group C and 24.1 ± 8 mmHg in Group O in 25th minute and the difference between the two groups was statistically significant at this time. We observed that consumption of prophylactic OLE had a reducing effect on IOP in the period before waking in anaesthesia. We believe it is necessary to investigate the effects of OLE on IOP in broad participation patient groups.