Background: Some patients develop long-term symptoms after Corona virus disease 2019 (COVID-19), and chronic fatigue syndrome (CFS) is one of the main symptoms. CFS is characterized by fatigue lasting for more than 6 months accompanied by sleep disorders, anxiety, and depression, which causes a certain degree of harm to both physiological and psychological aspects of the individual. Traditional Chinese exercises (TCEs) are an ancient Chinese therapy and has recently been reported to be effective for CFS. Therefore, we will conduct a systematic review and meta-analysis aiming to accurately evaluate the efficacy of TCEs on post-COVID-19 CFS and provide an alternative treatment for post-COVID-19 CFS. Methods: Seven databases (PubMed, Ovid Embase, Cochrane Library, Web of Science, Chinese National Knowledge Infrastructure (CNKI), China Biology Medicine (CBM), and Wanfang) will be searched from establishment to August 2022, and we will only include randomized controlled trials of TCEs for post-COVID-19 CFS. Two reviews will independently include the research according to the inclusion and exclusion criteria. Review Manager 5.2 software will be used to analyze the accepted literature, and the relative risk ratio (RR) and 95% confidence interval (CI) will be used as effect indicators for the outcome indicator dichotomous variables. For continuous variables, weighted mean difference (MD) and 95% CI will be used as effect indicators. The heterogeneity test will be assessed using the I ² statistic and Q statistic. The PEDro scale was used to evaluate the methodological quality of the included studies. Subgroup analysis was performed according to different TCEs, age, gender, and duration of CFS. Results: This systematic review and meta-analysis will evaluate the efficacy of TCEs in post-COVID-19 CFS. Conclusion: The results of this study will provide reliable evidence for the effects of TCEs for post-COVID-19 CFS on patients’ fatigue, anxiety, depression, sleep, and quality of life.

Patients with idiopathic scoliosis require regular radiation-less follow-up such as ultrasound. Automated labeling reduces traditional ultrasound manual labeling errors. We enrolled 80 patients with idiopathic scoliosis between February 2024 and June 2024. We evaluated both intra- and inter-operator reliability of the ultrasound curve angle (UCA) and ultrasound lamina angle (USLA) and compared three-dimensional ultrasound assessments with conventional X-ray imaging to evaluate the validity and reliability of ultrasound measurements (UCA and USLA) against established radiographic benchmarks, including Cobb angle, thoracic kyphosis, and lumbar lordosis. Reliability assessments were conducted using the intraclass correlation coefficient (ICC). The validity of the UCA and USLA measurements was rigorously analyzed by comparing them against established radiographic benchmarks using Pearson correlation coefficients and Bland–Altman plots. ICC analyses confirmed robust ultrasound measurement reliability. Validity evaluations revealed a pronounced linear correlation between the UCA and coronal Cobb angle. Bland–Altman plots showed a strong correlation between ultrasound and radiologic measurements in the coronal plane. Automated ultrasound represents a promising diagnostic tool for monitoring conservative treatments in the future.

Background: Chronic prostatitis (CP) refers to a disease characterized by local pain and discomfort, urination discomfort, and quality of life. Acupuncture (ACU) and moxibustion are widely used in the treatment of CP, and the curative effect is satisfactory. Several systematic reviews (SRs) and meta-analyzes have reported the effectiveness of ACU and moxibustion in treating patients with CP. However, the evidence is not systematically integrated. This overview aims to integrate and evaluate the reliability of these SRs and the evidence generated from the ACU and moxibustion for CP meta-analysis. Methods: We will make a comprehensive retrieval in seven databases as following: Embase, Cochrane Library, Pubmed, Chinese databases SinoMed (previously called the Chinese Biomedical Database), Chinese National Knowledge Infrastructure (CNKI), Chinese Scientific Journals Database (VIP), and Wanfang Data (WF). The time is limited from the construction of the library to May 2021. We will use the Assessment of Multiple Systematic Reviews-2 (AMSTAR-2) tool to evaluate methodological quality. Preferred Reporting Items for Systematic Reviews and Meta-analysis Protocols (PRISMA-P) will be used in the report checklist to assess the quality of reports in the study. The GRADE will be used to evaluate the included SRs and meta-analysis. Our reviewers will conduct SRs, qualification evaluation, data extraction, methodological quality and evidence quality screening in pairs. The outcomes of interest include: NIH-Chronic Prostatitis Symptom Index (NIH-CPSI), effective rate, other CP symptom scales, EPS-WBC, and adverse events. Evidence will be combined based on patient subgroups and results where appropriate. Results: The results will be published in a peer-reviewed journal. Trial registration number: INPLASY202150018. Conclusion: This overview will provide comprehensive evidence of ACU and moxibustion for patients with CP.

Review question / Objective: Manipulative therapy has been increasingly applied to alleviate those who suffer from chronic neck pain. This systematic review and meta-analysis of randomized controlled trials (RCTs) aimed to determine the efficacy of manipulative therapy for chronic neck pain. P: Patients with Chronic Neck Pain. I: Manipulative therapy. C: Exercise, rehabilitation, or other physical therapy. O: Pain intensity and Neck disability. S: Randomized controlled trials. Condition being studied: Pain in the neck is a disagreeable sensory and emotional experience associated with the potential or actual damage of tissue that affects the cervical region. Pain in the neck that lasts for a long period is a serious problem for public health that causes a lot of pressure. Manipulative therapy is usually considered an alternative treatment option with the advantages of fewer verse effects and lower treatment costs compared to exercise. Therefore, this study retrieved the relevant randomized controlled trials of manipulative therapy in the treatment of chronic neck pain and conducted a comprehensive quantitative analysis to offer an evidence-based reference for the clinical application of manipulative therapy.

Review question / Objective: Chronic fatigue syndrome (CFS) is a disease in which fatigue strikes or lasts for more than 6 months, accompanied by pain, sleep disturbance, anxiety, and depression. Moreover, it brings a heavy economic burden to society. Traditional Chinese exercises (TCEs) are a traditional Chinese medical treatment and have good efficacy on CFS, therefore, this systematic evaluation is to accurately evaluate the efficacy of TCEs on CFS. P: Patients with chronic fatigue syndrome. I: Traditional Chinese exercises. C: conventional exercise, acupuncture, physiotherapy, and other physical therapy methods. O: quality of life, fatigue, pain, sleep, anxiety, and depression. S: randomized controlled trials. Condition being studied: Chronic fatigue syndrome (CFS) is a disease in which fatigue strikes or lasts for more than 6 months, accompanied by pain, sleep disturbance, anxiety, and depression. Moreover, it brings a heavy economic burden to society. Traditional Chinese exercises (TCEs) are a traditional Chinese medical treatment and have good efficacy on CFS. Therefore, this systematic evaluation is to accurately evaluate the efficacy of TCEs on CFS, to provide an alternative therapy for clinical treatment of CFS.

INPLASY202280008 Study on manual therapy in the treatment of low back pain based on rs-fMRI: a protocol for systematic review and meta-analysis Keywords: manual therapy; low back pain; magnetic res…