Bisphosphonate-related osteonecrosis is an infrequent but potentially serious complication. Its treatment remains complex, and in some cases can be mutilating. Prevention, a correct diagnosis and opportune management are crucial. A cross-sectional study was made, interviewing 410 dentists with the aim of assessing their knowledge of the subject. Practically all of the dental professionals (99.7%) were found to lack sufficient knowledge of the prevention, diagnosis and management of bisphosphonate-related osteonecrosis. Actions including increased diffusion in the professional media and inclusion of the subject in training programs are needed in order to enhance the knowledge of bisphosphonate-related osteonecrosis among dentists and thus prevent complications in this group of patients. Key words:Knowledge, mexico, osteonecrosis, bisphosphonates.

Recurrent aphthous stomatitis (RAS) is a common disease in the oral cavity characterized by recurrent ulcers (RU). Usually, these cause acute pain without definitive treatment. The present study determines the efficacy of non-thermal plasma (NTP) for treating RU. NTP is applied to the patient’s RU using a radiofrequency generator connected to a point reactor. The power density applied to the ulcer is 0.50 W/cm², less than 4 W/cm², which is the maximum value without biological risk. Each patient received two treatments of three minutes each and spaced 60 min apart at a distance of 5 mm from the RU. From a sample of 30 ulcers in patients treated for RU with an average age of 37 years, they stated that the pain decreased considerably and without the need for ingestion of analgesics and antibiotics. Regeneration took place in an average of three days. The NTP proved to be an excellent therapeutic alternative for the treatment of RU since it has a rapid effect of reducing pain and inflammation, as well as adequate tissue regeneration.

A biopsy is performed for diagnostic purposes and provides valuable information through a histopathological study. It is possible to use a suture or some other surgical closure method for wound closure. This study determined wound healing time in an excisional biopsy in the mobile oral mucosa after using non-thermal atmospheric pressure plasma (NTAPP). The NTAPP has applied after the biopsy in two treatments for three minutes each and one hour apart. The repair time was between one and seven days, with an average of three days, considering as a reference of the repair time that the oral mucosa in the biopsy area took its color, consistency, and surface. None of the patients undergoing treatment with NTAPP showed adverse effects after a minimum of six months of clinical follow-up. The patients treated with NTAPP showed a significant reduction in the tissue repair time, without infection and the absence of postoperative pain, presenting an almost immediate recovery of oral functions; the patients did not require analgesics. The application of NTAPP to wounds after taking a biopsy of the mobile oral mucosa could be recommended as a safe and reliable alternative to repair tissue in this type of wound.

La artritis reumatoide (AR) es una enfermedad sistémica crónica inflamatoria caracterizada por una respuesta inmune patogénica que ocasiona daño articular el cual puede ser incapacitante e incluso condicionar una muerte prematura. Entre las articulaciones afectadas puede encontrarse la articulación temporomandibular (ATM) ocasionando dolor, crepitación, inflamación y limitación de los movimientos mandibulares. La disfunción de la ATM es una entidad muy común, por lo que el objetivo de este estudio fue determinar en qué medida los pacientes con AR tienen afección de la ATM comparado con pacientes sanos e identificar las principales diferencias en la presentación clínica, para lo cual se realizó un estudio de casos y controles. Se incluyeron 37 pacientes en cada grupo. En el grupo de pacientes con AR se encontró una afección de la ATM en el 75% de los pacientes (28 casos), mientras que en el grupo control solo el 13,5% (5 casos). Los hallazgos identificados en el grupo de pacientes con AR y disfunción de ATM fueron principalmente desviación mandibular, ruidos articulares, pérdida dental, dolor articular y limitación de la apertura. En este estudio se pudo identificar que existe un riesgo 82% (OR 19,9, IC<!-- --> <!-- -->=<!-- --> <!-- -->0,71-0,89) veces mayor de desarrollar disfunción de ATM en pacientes con AR comparado con pacientes sanos, por lo que resulta de suma importancia realizar revisiones periódicas de la ATM con el fin de identificar signos y síntomas tempranos para así evitar la progresión de la disfunción, lo cual se verá reflejado en una mejor nutrición y calidad de vida del paciente. Rheumatoid arthritis (RA) is a chronic systemic inflammatory disease characterised by a pathogenic immune response that causes joint damage that can be disabling and even cause premature death. The temporomandibular joint (TMJ) can also be affected, causing pain, crepitus, swelling, and limitation of mandibular movements. TMJ dysfunction is a very common condition, thus the aim of this study was to determine to what extent patients with RA have TMJ dysfunction compared with healthy patients and to identify the main differences in the clinical presentation. A case-control study was performed with the objective of identifying the main differences in the clinical presentation. A total of 37 patients were included in each group. In the group of patients with RA it was found that 75% of patients (28 cases) had TMJ dysfunction, while in the control group there were only 13.5% (5 cases). The findings identified in the group of patients with RA and TMJ dysfunction were mainly: mandibular deviation, joint sounds, tooth loss, joint pain, and limitation of the opening. This study was able to identify that there is an increased risk of 82% (OR 19.9, 95% CI<!-- --> <!-- -->=<!-- --> <!-- -->0.71-0.89) in developing TMJ dysfunction in patients with RA compared with healthy patients. It is concluded that it is important to perform periodic TMJ exploration to be able to identify early signs and symptoms of dysfunction to avoid progression. This would be reflected in better nutrition and quality of life of the patient.

Background/Objectives: Recurrent oral ulcers (ROUs) are a common condition that significantly impacts patients’ quality of life. This pilot study was conducted to evaluate the feasibility and preliminary results of using non-thermal plasma (NTP) compared to low-level laser therapy (LLLT) and placebo to treat these ulcers. Methods: A prospective, controlled, randomised, parallel-group pilot study was conducted using a convenience sample of 50 patients with ROUs. Patients were randomly assigned (2:2:1) to one of three groups: NTP (n = 20), LLLT (n = 20), and placebo (n = 10). Feasibility and preliminary data acquisition were the primary goals. Exploratory outcomes included ulcer size reduction and safety profile. This was a single-blinded trial, where participants and outcome assessors were masked to group assignment. Ulcer size, pain perception, and time to complete healing were measured. For statistical analysis, ANOVA was used, with a p-value ≤ 0.05. Results: The groups were comparable at baseline. Exploratory results suggest that NTP demonstrated a promising trend in accelerating healing, with a mean healing time difference of 5.5 days compared to LLLT (2.5 ± 1.9 days vs. 8.0 ± 4.3 days) and 7.1 days compared to placebo (2.5 ± 1.9 days vs. 9.6 ± 5.3 days) (p < 0.001). Regarding pain, NTP provided significant and sustained relief. Patients in the NTP group were asymptomatic on day 2, unlike the LLLT and placebo groups, where pain persisted significantly (NTP VAS score at 1 h: 1.1 ± 2.1 vs. LLLT/Placebo VAS score at 1 h: 3.4 ± 2.4 and 7.3 ± 1.9, respectively) (p < 0.001). NTP was well tolerated, and no adverse events were reported. Conclusions: This pilot study suggests that NTP is a potentially safe and effective therapy for recurrent oral ulcers. Preliminary results indicate that it may accelerate healing and offer superior pain relief, warranting a large-scale clinical trial to confirm these findings.

Background/Objectives: The integration of silver nanoparticles (AgNPs) into plastic materials has emerged as a promising strategy to provide biomedical and dental devices with an active antimicrobial barrier. In this review, we aimed to synthesize the scientific evidence published between 2013 and 2024 regarding the therapeutic efficacy, biocompatibility, and safety of AgNP-functionalized plastics by following the 2020 PRISMA guidelines. Methods: Searches were conducted in PubMed, Scopus, Web of Science, SciELO, and ScienceDirect. A total of 634 records were identified, of which 21 studies met the inclusion criteria after full-text evaluation. Results: Plastics containing AgNPs show a significant reduction in microbial load (Escherichia coli, Stafilococcus aureus, and Candida albicans) and exhibit controlled release of Ag⁺ ions, with generally low cytotoxicity levels. The most frequent applications included catheters, dental prostheses, dressings, and orthodontic resins. However, methodological heterogeneity and the scarcity of clinical trials limit the extrapolation of findings. Conclusions: AgNPs confer relevant therapeutic advantages to polymers, but long-term clinical studies are needed to confirm their safety and effectiveness.