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The article substantiates the relevance of the use of collagen-containing concentrate in the production of cottage cheese products for sports nutrition. The inclusion of cottage cheese products with a high content of collagen in the diet of athletes helps to strengthen the cartilage tissue of joints, improve the restoration of connective tissue of the ligamentous apparatus and reduce the pain threshold by increasing collagen production. Based on the study of the chemical composition of secondary products of the poultry processing industry, such chicken parts as skin, bone tissue and paws were selected to obtain a collagen-containing concentrate. A method for producing a dry collagen-containing concentrate has been developed. To obtain a collagen-containing concentrate, a method based on an enzymatic process using the papain enzyme for the hydrolysis of raw materials was chosen. This method allows you to preserve the biological value of collagen due to the gentle processing of raw materials. As a result of experimental studies, it was found that the collagen-containing concentrate contains polyunsaturated omega-3, omega-6 and omega-9 fatty acids with antioxidant properties. The result of the study of nutritional and biological value confirms the validity of the use of collagen-containing concentrate in the production of cottage cheese product for sports nutrition. A curd product enriched with collagen can be intended not only for athletes, but also for people who play sports for recreational purposes.

Background/Objectives: The aim of this study was to establish the multifactorial physiological effect of a functional curd product enriched with collagen-containing concentrate and phytochemical extracts of various natures, under conditions of in vivo experiment. Methods: Biomarkers, such as antioxidant activity (glutathione peroxidase, glutathione reductase, MDA), immune response (IgA, IgG, IgM, IL-6, TNF-α), and purine metabolism (uric acid, xanthine oxidase, 5′-nucleotidase) were selected for evaluation and their influence change. The model was white outbred rats (n = 45), randomly distributed into three groups: control (basic product), experimental group 1 (supplements of collagen-containing concentrate and extract of the composition of sea buckthorn and rosehips), and experimental group 2 (supplements of collagen-containing concentrate and extract of the composition of yarrow and sage). Results: In both experimental groups, a reliable increase in the enzymatic activity of the antioxidant system, a decrease in lipid peroxidation and the level of proinflammatory cytokines, an increase in immunoglobulins, and activation of 5′-nucleotidase were observed. The most pronounced effects were observed with the introduction of a curd product containing collagen-containing concentrate and sea buckthorn and rosehip extract. Conclusions: The scientific novelty of the study lies in the first comprehensive in vivo evaluation of the combined enrichment of a dairy product with collagen and plant extracts for a set of biomarkers. The data obtained confirm the physiological activity and functional properties of the developed product, which can be considered as a promising means of specialized and sports nutrition with proven biological action.

The article presents the results of a study on the effects of the wild medicinal plant Eminium regelii Vved. extract to the body of intact and subjected to emotional stress animals on the background of a long-term low dose of gamma-radiation. The reaction of the animal organism to the effects of radiation, emotional stress and the introduction of the Е. regelii extract were evaluated by the total content of leukocytes, absolute and relative content of lymphocytes (including CD3+, CD4+, CD8+), immunoregulatory index (IRI) and leukocyte migration inhibition reaction (LMIR). The experiments were performed on adult mongrel white rats of both sexes. At the early stage of the general adaptation syndrome (GAS) the injection of Е. regelii extract caused a decrease in the total number of lymphocytes, an increase in the number of CD4+ lymphocytes and leukocytes lymphokinproduction abilities. Late stage of GAS was indicated by increased CD3+ and CD4+ lymphocytes, and increased values of the immunoregulatory index.