Mei-Ling Chan

Mei-Ling Chan


Research Focus & Metrics

Academic Career Length

4Years (2023-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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25 May 2023 in Bioengineering
Verified
Journal Article
Open access
PDF file
YCYi-Chieh Chen
Yi-Chieh Chen
MCMing-Yi Chen
Ming-Yi Chen
TCTsung-Yi Chen
Tsung-Yi Chen
MCMei-Ling Chan
Mei-Ling Chan
YHYa-Yun Huang
Ya-Yun Huang
PAPatricia Angela Abu
Patricia Angela Abu
As the popularity of dental implants continues to grow at a rate of about 14% per year, so do the risks associated with the procedure. Complications such as sinusitis and nerve damage are not uncommon, and inadequate cleaning can lead to peri-implantitis around the implant, jeopardizing its stability and potentially necessitating retreatment. To address this issue, this research proposes a new system for evaluating the degree of periodontal damage around implants using Periapical film (PA). The system utilizes two Convolutional Neural Networks (CNN) models to accurately detect the location of the implant and assess the extent of damage caused by peri-implantitis. One of the CNN models is designed to determine the location of the implant in the PA with an accuracy of up to 89.31%, while the other model is responsible for assessing the degree of Peri-implantitis damage around the implant, achieving an accuracy of 90.45%. The system combines image cropping based on position information obtained from the first CNN with image enhancement techniques such as Histogram Equalization and Adaptive Histogram Equalization (AHE) to improve the visibility of the implant and gums. The result is a more accurate assessment of whether peri-implantitis has eroded to the first thread, a critical indicator of implant stability. To ensure the ethical and regulatory standards of our research, this proposal has been certified by the Institutional Review Board (IRB) under number 202102023B0C503. With no existing technology to evaluate Peri-implantitis damage around dental implants, this CNN-based system has the potential to revolutionize implant dentistry and improve patient outcomes.

4 July 2023 in Bioengineering
Verified
Journal Article
Open access
PDF file
奕毛奕程 毛
奕程 毛
YHYen-Cheng Huang
Yen-Cheng Huang
TCTsung-Yi Chen
Tsung-Yi Chen
Kuo-chen LiKuo-chen Li
Kuo-chen Li
YLYuan-Jin Lin
Yuan-Jin Lin
PAPatricia Angela Abu
Patricia Angela Abu
Furcation defects pose a significant challenge in the diagnosis and treatment planning of periodontal diseases. The accurate detection of furcation involvements (FI) on periapical radiographs (PAs) is crucial for the success of periodontal therapy. This research proposes a deep learning-based approach to furcation defect detection using convolutional neural networks (CNN) with an accuracy rate of 95%. This research has undergone a rigorous review by the Institutional Review Board (IRB) and has received accreditation under number 202002030B0C505. A dataset of 300 periapical radiographs of teeth with and without FI were collected and preprocessed to enhance the quality of the images. The efficient and innovative image masking technique used in this research better enhances the contrast between FI symptoms and other areas. Moreover, this technology highlights the region of interest (ROI) for the subsequent CNN models training with a combination of transfer learning and fine-tuning techniques. The proposed segmentation algorithm demonstrates exceptional performance with an overall accuracy up to 94.97%, surpassing other conventional methods. Moreover, in comparison with existing CNN technology for identifying dental problems, this research proposes an improved adaptive threshold preprocessing technique that produces clearer distinctions between teeth and interdental molars. The proposed model achieves impressive results in detecting FI with identification rates ranging from 92.96% to a remarkable 94.97%. These findings suggest that our deep learning approach holds significant potential for improving the accuracy and efficiency of dental diagnosis. Such AI-assisted dental diagnosis has the potential to improve periodontal diagnosis, treatment planning, and patient outcomes. This research demonstrates the feasibility and effectiveness of using deep learning algorithms for furcation defect detection on periapical radiographs and highlights the potential for AI-assisted dental diagnosis. With the improvement of dental abnormality detection, earlier intervention could be enabled and could ultimately lead to improved patient outcomes.

1 February 2023 in Sensors
Verified
Journal Article
Open access
PDF file
SCShih-Lun Chen
Shih-Lun Chen
HCHE SHENG CHOU
HE SHENG CHOU
SKShih-Yao Ke
Shih-Yao Ke
CCChiung-An Chen
Chiung-An Chen
TCTsung-Yi Chen
Tsung-Yi Chen
Kuo-chen LiKuo-chen Li
Kuo-chen Li
It has always been a major issue for a hospital to acquire real-time information about a patient in emergency situations. Because of this, this research presents a novel high-compression-ratio and real-time-process image compression very-large-scale integration (VLSI) design for image sensors in the Internet of Things (IoT). The design consists of a YEF transform, color sampling, block truncation coding (BTC), threshold optimization, sub-sampling, prediction, quantization, and Golomb–Rice coding. By using machine learning, different BTC parameters are trained to achieve the optimal solution given the parameters. Two optimal reconstruction values and bitmaps for each 4 × 4 block are achieved. An image is divided into 4 × 4 blocks by BTC for numerical conversion and removing inter-pixel redundancy. The sub-sampling, prediction, and quantization steps are performed to reduce redundant information. Finally, the value with a high probability will be coded using Golomb–Rice coding. The proposed algorithm has a higher compression ratio than traditional BTC-based image compression algorithms. Moreover, this research also proposes a real-time image compression chip design based on low-complexity and pipelined architecture by using TSMC 0.18 μm CMOS technology. The operating frequency of the chip can achieve 100 MHz. The core area and the number of logic gates are 598,880 μm2 and 56.3 K, respectively. In addition, this design achieves 50 frames per second, which is suitable for real-time CMOS image sensor compression.

30 December 2024 in Electronics
Verified
Journal Article
Open access
PDF file
MCMei-Ling Chan
Mei-Ling Chan
YYYing Yu
Ying Yu
PCPohan Chang
Pohan Chang
TCTsung-Yi Chen
Tsung-Yi Chen
HWHok-Long Wong
Hok-Long Wong
SCShih-Lun Chen
Shih-Lun Chen
With shifts in lifestyle and dietary patterns, obesity has become an increasing health issue among younger demographics, particularly affecting young adults. This trend is strongly associated with a heightened risk of developing chronic diseases, especially cardiovascular conditions. However, conventional health monitoring systems are often limited to basic parameters such as heart rate, pulse pressure (PP), and systolic blood pressure (SBP), which may not provide a comprehensive assessment of cardiac health. This study introduces an intelligent heart health monitoring system that leverages the Internet of Things (IoT) and advanced sensor technologies. By incorporating IoT-based sensors, this system aims to improve the early detection and continuous monitoring of cardiac function in young obese women. The research employed a TERUMO ES-P2000 to measure blood pressure and a PhysioFlow device to assess noninvasive cardiac hemodynamic parameters. Through precise sensor data collection, the study identified key indicators for monitoring cardiovascular health. Machine learning models and big data analysis were utilized to predict cardiac index (CI) values based on the sensor-derived inputs. The findings indicated that young obese women showed significant deviations in blood pressure (SBP and PP) and cardiac hemodynamic metrics (SVI, EDV, and ESV) at an early stage. The implementation of signal processing techniques and IoT sensors enhanced the CI prediction accuracy from 33% (using basic parameters like heart rate, PP, and SBP) to 66%. Moreover, the integration of extra sensor-based parameters, such as Stroke Volume Index (SVI) and Cardiac Output (CO), along with the use of color space transformations, successfully improved the prediction accuracy of the original data by 36.68%, increasing from 53.33% to 90.01%. This represents a significant improvement of 30.01% compared to the existing technology’s accuracy of 60%. These results underscore the importance of utilizing sensor-derived parameters as critical early indicators of cardiac function in young obese women. This research advances smart healthcare through early cardiovascular risk assessment using AI and noninvasive sensors.

18 April 2026 in Bioengineering
Verified
Journal Article
Open access
PDF file
CCChih-Hao Chang
Chih-Hao Chang
MCMei-Ling Chan
Mei-Ling Chan
YFYu-Hung Fang
Yu-Hung Fang
PHPo-Lin Huang
Po-Lin Huang
TCTsung-Yi Chen
Tsung-Yi Chen
PAPatricia Angela Abu
Patricia Angela Abu
Concurrent with the rising consumption of ultra-processed, high-calorie diets and the decline in physical activity, obesity and related cardiovascular conditions among young adults have continued to increase, becoming an important global public health concern. This study integrates non-invasive Internet of Things (IoT) sensing devices, including the TERUMO ES-P2000 blood pressure monitor (Terumo Corp., Tokyo, Japan) and the PhysioFlow PF07 Enduro cardiac hemodynamic analyzer (Manatec Biomedical, Poissy, France), with an artificial neural network (ANN) for cardiac index (CI) prediction. Through appropriate data preprocessing and model training strategies, the generalization ability and stability of the proposed CI prediction model were significantly enhanced. Experimental results demonstrate that, when using three physiological parameters as input, the ANN achieved a classification accuracy of 97.78%, substantially outperforming traditional approaches. Even under two-parameter input conditions, the model maintained strong predictive performance. These findings confirm the effectiveness and practical potential of the proposed framework for real-time, non-invasive CI assessment. Moreover, this research has received rigorous assessment and approval from the Institutional Review Board (IRB) under application number 202501987B0.