Vitis viniferaedible leaf extract loaded on a Carbopol gel was prepared to maximize the wound healing and anti-MRSA properties. The extract's mode of action has been comprehensively investigated byin vitro,in vivo, andin silicoexperiments.

Microparticles (MPs) are vesicles of less than 1 mu m in diameter (submicron vesicles) shed from plasma membranes to cell activation, injury, and apoptosis response. They consisted of membrane proteins and cytosolic material from the cell they originated. These vesicles are vital mediators of pathological and physiological cellular processes. Polycystic ovary syndrome (PCOS) is a regular endocrine, menstrual and metabolic condition that affects 10-15% of females in their reproductive period. Numerous researches have described the association between low-grade chronic inflammation and PCOS; however, the relation is not well understood. Chronic lowgrade inflammation is reflected as a risk factor for cardiovascular disease, atherosclerosis, and endothelial dysfunction, and it is linked to abdominal obesity and insulin resistance (IR). MPs may be useful biomarkers for the early detection of cardiovascular disease and thrombosis in PCOS patients. In March 2020, the novel severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) became pandemic, wreaking havoc on healthcare systems worldwide and the global economy. Obesity, diabetes, and cardiovascular disease have all been linked to COVID-19 increased risk of infection. PCOS patients have recently been identified as an underserved and potentially high-risk demographic for COVID-19 problems. This article tried to review and present recent studies that explored the role of microparticles in polycystic ovarian syndrome.

The existence of Group B Streptococcus (GBS) in the rectovaginal area during pregnancy and labor is linked to disease and even death in neonates. However, the extent of GBS colonization in pregnant women in Saudi Arabia has not been fully established. The goal of this study was to ascertain the prevalence of Group B Streptococcus (GBS) colonization in pregnant women in Saudi Arabia, where GBS screening is not routinely conducted. This retrospective study involved 1201 Saudi women at ≥28 weeks