Dental caries in preschool children is prevalent worldwide, but data regarding its magnitude and associated factors were not available for preschool children in Zhejiang Province, China. This study examines the dental caries situation and its associated factors in Zhejiang Province. A total of 1591 children aged 3–5 years and their parents or caregivers were enrolled in this study. The condition of their teeth was assessed by three dental technicians qualified to WHO 2013 criteria. A structured questionnaire was completed by the children’s parents or caregivers. A logistic regression analysis was used to analyze the risk factors that may be associated with dental caries occurring among preschool children. Caries prevalence (dmft> 0) of 3–5 year old children in Zhejiang Province was 70.4%. The mean decayed, missing and filled teeth (dmft) scores of the 3, 4 or 5 year old children surveyed were 2.96 ± 4.07, 4.42 ± 4.66, and 5.75 ± 5.19 respectively. The negative binomial regression model found that higher dental caries prevalence was found in children as age increased, with lower body mass index (BMI), with longer breastfeeding duration and with fewer hours of sleep. The dental caries prevalence and dmft score of 3–5-year-old children in Zhejiang Province was high, and it was associated with age, BMI, breastfeeding duration and hours slept.

Bacterial adhesion to dental materials’ surfaces is the initial cause of dental materials-related infections. Therefore, inhibiting bacterial adhesion is a critical step in preventing and controlling these infections. To this end, it is important to know how the properties of dental materials affect the interactions between microorganisms and material surfaces to produce materials without biological contamination. This manuscript reviews the mechanism of bacterial adhesion to dental materials, the relationships between their surface properties and bacterial adhesion, and the impact of bacterial adhesion on their surface properties. In addition, this paper summarizes how these surface properties impact oral biofilm formation and proposes designing intelligent dental material surfaces that can reduce biological contamination.

Emerging research underscores the gut-brain axis in mental disorder pathophysiology, yet the oral microbiome's contribution to mental health remains underexplored. Elucidating oral microbial signatures in mental and neurological disorders may reveal novel pathobiological mechanisms and advance biomarker discovery for precision diagnostics and microbiota-targeted interventions. This systematic review and meta-analysis investigates oral microbiota alterations across 6 different mental disorders, by synthesizing data from 20 case-control studies retrieved from PubMed, Embase, and Cochrane Library. Relative microbial abundance and beta diversity indices were extracted from between-group comparisons. Random-effects meta-analyses were conducted for alpha diversity to characterize microbiota differences between patients and controls. Key findings included a significantly higher Simpson Index in patients (SMD = 0.42; 95% CI, 0.25 to 0.60) compared to controls. Beta diversity varied significantly only in SZ and MDD. Condition-specific variations in microbial abundance were observed: Rothia enrichment in ASD, overrepresentation of H₂S-producing genera in SZ, and reduced Solobacterium and Leptotrichia in MDD. Collectively, the meta-analytical synthesis suggests alterations in oral microbiota diversity across mental disorders. Disease-associated microbial shifts highlight the oral microbiome as a candidate factor warranting further investigation for potential diagnostic applications and microbial-targeted therapeutic strategies.

Children with special health care needs (CSHCN) cannot perform daily personal care and participate in social activities similar to healthy children, thus requiring special medical services. In the research field of oral rehabilitation, study focuses primarily on treatment under dental general anaesthesia (DGA). This study aims to compare the perioperative treatment of CSHCN under DGA with healthy children. A PubMed database search was performed using the MeSH and non-MeSH descriptors: 'children with special health care needs'; 'intellectual disability'; 'dental treatment'; 'endodontics'; 'restorative treatment'; 'filling treatment'; 'extraction treatment'; 'general anaesthesia' and 'sedation'. No time restrictions were applied. Literature reviews, systematic reviews, meta-analyses and clinical and preclinical trials were included. The narrative review delineates a comprehensive framework for DGA in CSHCN. This encompasses a rigorous preoperative assessment (encompassing patient education, DGA-specific, and anaesthesia evaluation), a meticulous perioperative management protocol from medication to complication handling, and the execution of specialized intraoperative oral treatments. While DGA's primary advantage lies in enabling definitive, single-session comprehensive care, significant challenges persist, including the management of perioperative complications and ensuring effective postoperative follow-up for long-term success, all operating within the context of specific legal authorities governing dentist-administered anaesthesia. DGA in oral management of CSHCN necessitates tailored anaesthetic planning, meticulous postop care and a systematic regulatory framework.

目的：通过卡托普利来抑制金属基质蛋白酶的活性以提高粘接界面的稳定性。方法：采用不同浓度的卡托普利乙醇溶液和卡托普利乙醇/水溶液对人离体牙牙质表面进行预处理，通过场发射扫描电镜观察卡托普利预处理对牙质表面形貌的影响；在此基础上通过两种自酸蚀粘接剂对牙质进行粘接，表征即刻粘接强度，并通过老化处理，评价卡托普利预处理对粘接持久性的影响。结果：扫描电镜结果提示，卡托普利溶液可以部分去除沾污层并暴露牙质胶原。基于扫描电镜结果，选择0.15 g/mL卡托普利乙醇溶液（50%乙醇）处理30 s作为预处理条件，通过可乐丽菲露 SE BOND进行牙质粘接，即刻微拉伸强度从（30.80±4.70）MPa提升至（37.48±3.20）MPa（P＜0.05）；老化处理1年后，对照组微拉伸强度显著下降[（22.90±6.82）MPa，P＜0.05]，而实验组微拉伸强度没有明显的变化[（36.56±5.10）MPa，P＞0.05]。用可乐丽菲露 S3 BOND进行牙质粘接，对照组的即刻微拉伸强度为（31.33±4.11）MPa，与实验组（34.70±4.07）MPa差异无统计学意义（P＞0.05）；老化处理1年后，实验组的微拉伸强度高于对照组[分别为（32.36±3.58）MPa和（21.43±6.27）MPa，P＜0.05]。结论：卡托普利预处理不仅可以提高自酸蚀粘接的即刻粘接强度，而且改善了粘接的持久性。