Sophie Williams

Prof. Sophie Williams

orcid

Research Focus & Metrics

Academic Career Length

23Years (2004-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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1 December 2006 in Tribology International
Verified
Journal Article
Closed access
Yu YanYu Yan
Yu Yan
ANAnne Neville
Anne Neville
DDDuncan Dowson
Duncan Dowson
SWSophie Williams
Sophie Williams

1 December 2007 in Clinical Orthopaedics and Related Research
Verified
Journal Article
Closed access
SWSophie Williams
Sophie Williams
ASAnton Schepers
Anton Schepers
GIGraham Isaac
Graham Isaac
CHCath Hardaker
Cath Hardaker
EIEileen Ingham
Eileen Ingham
JFJohn Fisher
John Fisher
The performance of novel ceramic-on-metal bearing couples has been compared with metal-on-metal and ceramic-on-ceramic bearing couples in laboratory and short-term clinical studies. Laboratory studies compared ceramic-on-metal with metal-on-metal and ceramic-on-ceramic bearings with diameters of 28 and 36 mm under standard conditions and under adverse conditions with head loading on the rim of the cup. Clinical studies compared metal ion levels in ceramic-on-metal with metal-on-metal, ceramic-on-ceramic, and ceramic-on-polyethylene bearings in a randomized prospective study. In the laboratory studies, friction, wear, and ion levels were lower in ceramic-on-metal bearings compared with metal-on-metal, with results similar to ceramic-on-ceramic couples. Under adverse conditions and rim loading, all bearings showed increased wear with lower wear and absence of stripe wear in ceramic-on-metal compared with metal-on-metal bearings. Short-term studies in 31 patients at 6 months revealed lower metal ion levels (cobalt and chromium) in those with ceramic-on-metal compared with metal-on-metal bearings. Level of Evidence: Level II, therapeutic study. See the Guidelines for Authors for a complete description of levels of evidence.

5 September 2005 in Journal of Biomechanics
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Journal Article
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PDF file
SWSophie Williams
Sophie Williams
DJDavood Jalali-Vahid
Davood Jalali-Vahid
CBClaire Brockett
Claire Brockett
ZJZhongmin Jin
Zhongmin Jin
MSMartin H. Stone
Martin H. Stone
JFJohn Fisher
John Fisher

26 April 2004 in Journal of Biomedical Materials Research Part B: Applied Biomaterials
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Journal Article
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SWSophie Williams
Sophie Williams
TSTodd D. Stewart
Todd D. Stewart
EIEileen Ingham
Eileen Ingham
MSMartin H. Stone
Martin H. Stone
JFJohn Fisher
John Fisher

29 January 2013 in Journal of Biomedical Materials Research Part B: Applied Biomaterials
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Journal Article
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PDF file
SWSophie Williams
Sophie Williams
MAMazen Al‐Hajjar
Mazen Al‐Hajjar
GIGraham H. Isaac
Graham H. Isaac
JFJohn Fisher
John Fisher

11 February 2022 in Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine
Verified
Journal Article
Open access
GPGregory M Pryce
Gregory M Pryce
BSBismaya Sabu
Bismaya Sabu
MAMazen Al-Hajjar
Mazen Al-Hajjar
RWRuth K Wilcox
Ruth K Wilcox
JTJonathan Thompson
Jonathan Thompson
SWSophie Williams
Sophie Williams
Total Hip Arthroplasty (THA) is one of the most common and successful surgical interventions. The survivorship at 10 years for the most commonly used systems is over 95%. However, the incidence of revision is usually much higher in the 0–1 year time period following the intervention. The most common reason for revision in this early time period is dislocation and subluxation, which may be defined as complete or permanent, and partial or temporary loss of contact between the bearing surfaces respectively. This study comprises the development of a geometric model of bone and an in situ total hip replacement, to predict the occurrence and location of bone and component impingement for a wide range of acetabular cup positions and for a series of frequently practiced activities of daily living. The model developed predicts that anterior-superior component impingement is associated with activities that result in posterior dislocation. The incidence may be reduced by increased cup anteversion and inclination. Posterior-inferior component impingement is associated with anterior dislocation activities. Its incidence may be reduced by decreased cup anteversion and inclination. A component impingement-free range was identified, running from when the cup was positioned with 45° inclination and 25° anteversion to 70° inclination and 15°–20° anteversion.