Vaccination is one of the most useful preventive interventions in healthcare. The purpose of our study was to gain overview of the opinions, knowledge, and engagement in vaccination practices among medical students (MS) and junior doctors (JD) in Europe. The survey was distributed from March 2016 until August 2016 via the e-mail and social media of the European Medical Students’ Association. In total, 1821 responses from MS and JD from 34 countries in the European region were analysed. The majority of respondents agreed that vaccines are useful (98.7%) and effective (97.2%). Although the necessity of revaccination was supported by 99.2%, only 68.0% of the respondents went through with it. Even though the potential benefit of the flu vaccination seems to be acknowledged by our participants, only 22.1% of MS and JD declared getting the flu shot every or every other season. MS and JD were in favour of specific mandatory vaccination for medical staff (86.0%) and medical students (82.7%). Furthermore, we analysed the self-reported vaccination coverage of our participants regarding 19 vaccines. Of the respondents, 89.5% claimed to provide advice about vaccination to their friends and family. In conclusion, European MS and JD have a very positive attitude towards vaccination. However, their behaviour and knowledge demonstrate certain gaps which should be further addressed in medical education.

Nowadays, in people’s perceptions, the return to roots in all aspects of life is an increasing temptation. This tendency has also been observed in the medical field, despite the availability of high-level medical services with many years of research, expertise, and trials. Equilibrium is found in the combination of the two tendencies through the inclusion of the scientific experience with the advantages and benefits provided by nature. It is well accepted that the nutritional and medicinal properties of honey are closely related to the botanical origin of the plants at the base of honey production. Despite this, people perceive honey as a natural and subsequently a simple product from a chemical point of view. In reality, honey is a very complex matrix containing more than 200 compounds having a high degree of compositional variability as function of its origin. Therefore, when discussing the nutritional and medicinal properties of honey, the importance of the geographical origin and its link to the honey’s composition, due to potential emerging contaminants such as Rare Earth Elements (REEs), should also be considered. This work offers a critical view on the use of honey as a natural superfood, in a direct relationship with its botanical and geographical origin.

Driven by rapid technological development, the rising need for rare earth elements (REEs) has led to increased extraction, processing, and utilization of these materials in new technologies. Nevertheless, the waste produced by these processes is often inadequately managed, resulting in the release of these elements into the environment, contaminating water sources and the food chain, and ultimately impacting both humans and animals. Recent studies have underlined the toxic potential of these elements, raising major concerns regarding human health. Given the exponential increase in the use of this group of elements, it is essential to acquire a deep understanding of the adverse consequences associated with REEs. This review aims to examine the neurotoxic effects of lanthanum, an element of this group that has garnered significant attention from the scientific community, by providing a comprehensive overview of the mechanisms underlying its toxicity.

Anterior cruciate ligament (ACR) rupture is a frequent injury in professional sports players. We conducted a retrospective cohort study, including 41 professional female handball players, undergoing ACR reconstruction surgery, using a Ligament Advanced Reinforcement System (LARS) graft (n = 12) or a Soft Tissue (ST) graft (n = 29). After return-to-play, the patients were asked to take a survey, reporting subjective and objective performance indexes before the injury and after return-to-play. Time from surgery to first practice and to return-to-play were significantly shorter in the LARS group (3.92 ± 1.14 vs. 6.93 ± 2.19 months, p < 0.001 and 4.71 ± 1.2 vs. 8.81 ± 2.9, respectively). While there was no difference between postoperative mean time on court, number of goals/match, number of matches played at 6 months return-to-play and 50 m, 100 m and gate-to-gate sprint times, there was a significantly greater increase in preoperative times in the ST group than in the LARS group (1.45 ± 1.05 s vs. 0.21 ± 0.58 s slower than preoperatively, p < 0.001 for 50 m; 1.09 ± 0.95 s vs. 0.08 ± 1 s, p = 0.01 for 100 m; 1.66 ± 1 s vs. 0.21 ± 0.66 s for gate-to-gate). In conclusion, LARS grafts provide a faster recovery time and better functional outcome, significantly impacting the performance of professional handball players.

Background: Research in the intensive care unit (ICU), which involves critically ill patients, families and healthcare professionals, poses significant ethical challenges. The aim of this PRISMA-guided systematic review is to identify major challenges for research ethics in the ICU. Methods: Pubmed and Scopus databases were searched in November-December 2024 for papers discussing theoretical concepts or specific aspects related to ethical issues in ICU research, retaining 70 papers on ICU research challenges, difficulties or controversies. Results: A total of 10 papers described general concepts related to research ethics in the ICU, 16 studies focused on the methodology or some of the study steps, and 6 papers focused on ICU trials, while 38 studies focused on special patient categories or special situations of critical patients. None of the included papers addressed all of the issues we identified regarding the ethical challenges. Conclusions: ICU research is challenging from a moral point of view. Significant ethical difficulties arise during the design and implementation phases, hampering the study's exactness. Being a vulnerable population with limited decision-making capacity and research-associated risks, alternative consent methods need to be considered. This systematic review provides a checklist of aspects that could generate ethical dilemmas and might constitute a starting point in the conduct of research studies, preventing unethical research.

Introduction. In the context of the Coronavirus Disease (COVID-19) pandemic, the extent of the damage in the worldwide population and health systems forced governments to find rapid and efficient countermeasures. Thus, global efforts are made to combat this disease and among the identified possible solutions to enforce the frontline workforce is to allow medical and nursing students to help in medical care. This survey proposes to assess the Romanian students’ self-perceived preparedness, considering their theoretical and practical knowledge. Methods. The survey was based on an 11-item form which aimed to evaluate the preparedness of the students to efficiently protect against the COVID-19 infection in a hospital setting, the overall willingness of the students to volunteer and the possible barriers that might prevent their involvement. For this purpose, a total number of 1021 responders, from which 18% nursing students and 82% medical students, from public and private medical schools of Romania, were included. Data processing was made using a free trial of GraphPad PRISM 8.0. The calculated parameters were: mean value, standard deviation, and confidence intervals (CI) and the level of significance was P<0.05. Results. Based on the collected data, we evidenced that the majority of the respondents (93%) acknowledged practical skills as a main positive factor for the decision to join the healthcare frontline. A strong, positive correlation between the self-perceived practical skills level, preparedness and the willingness to voluntarily involve in medical assistance was found. Conclusion. A significantly high level of practical skills and preparedness level in self-protecting effectively against COVID-19 was mainly seen in the following subgroups: the nursing students and the students that had previously been part of organized medical volunteer structures, revealing the practical experience to be a determining factor of preparedness.