The psychological treatment of comorbid post-traumatic stress disorder (PTSD) and substance use disorder (SUD) is clinically challenging, and outcomes are often poor.This paper describes a systemat... Antecedentes: El tratamiento psicológico del trastorno de estrés postraumático (TEPT) comórbido con trastorno por uso de sustancias (TUS) es un desafío clínico y los resultados suelen ser deficient... 背景: 创伤后应激障碍 (PTSD) 和物质使用障碍 (SUD) 共病的心理治疗在临床上具有挑战性,结果通常很差。目的: 本文描述了一项旨在确定一些针对成人和青少年已建立的心理方法相较于单独 SUD 干预或其他积极方法的当前疗效的系统综述和元分析,遵循了预注册的方案。方法: 本综述遵循 PRISMA 和 Cochrane 协作指南。所有作者均使用 Cochrane 标准进行数据提取和误差风险...
Several types of psychological treatment for posttraumatic stress disorder (PTSD) are considered well established and effective, but evidence of their long-term efficacy is limited. This systematic review and meta-analysis aimed to investigate the long-term outcomes across psychological treatments for PTSD. MEDLINE, Cochrane Library, PTSDpubs, PsycINFO, PSYNDEX, and related articles were searched for randomized controlled trials with at least 12 months of follow-up. Twenty-two studies (N = 2638) met inclusion criteria, and 43 comparisons of cognitive behavioral therapy (CBT) were available at follow-up. Active treatments for PTSD yielded large effect sizes from pretest to follow-up and a small controlled effect size compared with non-directive control groups at follow-up. Trauma-focused treatment (TFT) and non-TFT showed large improvements from pretest to follow-up, and effect sizes did not significantly differ from each other. Active treatments for comorbid depressive symptoms revealed small to medium effect sizes at follow-up, and improved PTSD and depressive symptoms remained stable from treatment end to follow-up. Military personnel, low proportion of female patients, and self-rated PTSD measures were associated with decreased effect sizes for PTSD at follow-up. The findings suggest that CBT for PTSD is efficacious in the long term. Future studies are needed to determine the lasting efficacy of other psychological treatments and to confirm benefits beyond 12-month follow-up.
27 August 2020 in European Journal of Psychotraumatology
During the current COVID-19 pandemic, the people in Europe are exposed to self-isolation, quarantine, job loss, risk of contracting COVID-19, or grief of loved ones. Such a complex array of stresso... Antecedentes: Durante la actual pandemia de COVID-19, las personas en Europa están expuestas a autoaislamiento, cuarentena, pérdida de empleo, riesgo de contraer COVID-19 o duelo de sus seres queri... 背景:在当前COVID 19大流行期间, 欧洲人民面临自我隔离, 隔离, 失业, 感染COVID-19的风险或丧亲之痛。如此复杂的一系列应激源可能导致适应障碍或创伤后应激障碍症状。本研究方案描述了由欧洲创伤应激研究学会 (ESTSS) 发起的一项研究, 以研究COVID-19大流行对个欧洲国家的适应障碍症状的影响。 目的:纵向线上队列研究旨在 (1) 探查10个欧洲国家对COVID-19大流...
25 October 2019 in European Archives of Psychiatry and Clinical Neuroscience
Psychopathology in women after childbirth represents a significant risk factor for parenting and infant mental health. Regarding child development, these infants are at increased risk for developing unfavorable attachment strategies to their mothers and for subsequent behavioral, emotional and cognitive impairments throughout childhood. To date, the specific efficacy of an early attachment-based parenting group intervention under standard clinical outpatient conditions, and the moderators and mediators that promote attachment security in infants of mentally ill mothers, have been poorly evaluated. This randomized controlled clinical trial tests whether promoting attachment security in infancy with the Circle of Security (COS) Intervention will result in a higher rate of securely attached children compared to treatment as usual (TAU). Furthermore, we will determine whether the distributions of securely attached children are moderated or mediated by variations in maternal sensitivity, mentalizing, attachment representations, and psychopathology obtained at baseline and at follow-up. We plan to recruit 80 mother-infant dyads when infants are aged 4-9 months with 40 dyads being randomized to each treatment arm. Infants and mothers will be reassessed when the children are 16-18 months of age. Methodological aspects of the study are systematic recruitment and randomization, explicit inclusion and exclusion criteria, research assessors and coders blinded to treatment allocation, advanced statistical analysis, manualized treatment protocols and assessments of treatment adherence and integrity. The aim of this clinical trial is to determine whether there are specific effects of an attachment-based intervention that promotes attachment security in infants. Additionally, we anticipate being able to utilize data on maternal and child outcome measures to obtain preliminary indications about potential moderators of the intervention and inform hypotheses about which intervention may be most suitable when offered in a clinical psychiatric outpatient context. Current Controlled Trials ISRCTN88988596