Ovarian cancer is a malignant disease that affects thousands of patients every year. Currently, we use surgical techniques for early-stage cancer and chemotherapy treatment combinations for advanced stage cancer. Several novel therapies are currently being investigated, with gene therapy and stem cell therapy being the corner stone of this investigation. We conducted a thorough search on PubMed and gathered up-to-date information regarding epithelial ovarian cancer therapies. We present, in the current review, all novel treatments that were investigated in this field over the past five years, with a particular focus on local treatment.

Background: Laparoscopic myomectomy has become popular and an attractive approach for the treatment of uterine myoma. Despite its unquestionable benefit to the patient concern has also been raised about its safety during pregnancy labour. The potential risks of uterine rupture are believed to be high. Aim: To assess the magnitude of uterine rupture during pregnancy and labor and possible causal factors following laparoscopic myomectomy. Methods: A literature search performed using web browser Google, and web sites as, High wire press, world laparoscopy hospital, Springer link and PubMed, Medline. Results: There were few references for incidents of uterine rupture after laparoscopic myomectomy in this article review. There are no enough data comparing transverse and vertical incisions, single or multilayer wound closure with respect to scar integrity. These seemingly remote but possible causal factors are discussed. Conclusion: Uterine rupture during pregnancies following laparoscopic myomectomy is possible but rare. The following review article shows that doesn't prove the suspicion that the laparoscopic myomectomy approach increases significantly the risk for uterine rupture during pregnancy. Even with this rarity, there is need to investigate this matter in-depth