Carlos Kleber Z. Andrade

Dr. Carlos Kleber Z. Andrade

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Research Focus & Metrics

Academic Career Length

25Years (2002-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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16 May 2011 in Organic & Biomolecular Chemistry
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Journal Article
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ABAngélica de Fátima S. Barreto
Angélica de Fátima S. Barreto
OVOtilie E. Vercillo
Otilie E. Vercillo
MBMike A. Birkett
Mike A. Birkett
JCJohn C. Caulfield
John C. Caulfield
LWLudger A. Wessjohann
Ludger A. Wessjohann
CACarlos Kleber Z. Andrade
Carlos Kleber Z. Andrade
A wide range of N-alkylglycines (peptoids) can be efficiently prepared viaUgi reactions using microwave irradiations. The results confirm the versatility and efficiency of the methodology for the preparation of functionalized peptoids. The products can be used in consecutive Ugi reactions to yield cyclic peptoids of potential biological interest.

1 March 2011 in Journal of the Brazilian Chemical Society
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Journal Article
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ABAngélica de Fátima S Barreto
Angélica de Fátima S Barreto
OVOtilie E Vercillo
Otilie E Vercillo
CACarlos Kleber Z. Andrade
Carlos Kleber Z. Andrade
Various α-acyloxy carboxyamides were easily obtained combining three building blocks in one step: a carboxylic acid, an aldehyde and an isonitrile (Passerini reaction), using microwave irradiation under solvent-free conditions. The products were obtained in good yields (61-90%) and in short reaction times (< 5 min), using two different temperatures (60 and 120 ºC). At 120 ºC, the yields were higher and the reactions faster (< 1 min). Most of the obtained products are multifunctional allowing their application in consecutive Passerini reactions

31 March 2024 in Tetrahedron
Verified
Journal Article
Closed access
LMLuan A. Martinho
Luan A. Martinho
CACarlos Kleber Z. Andrade
Carlos Kleber Z. Andrade

1 January 2013 in Journal of the Brazilian Chemical Society
Verified
Journal Article
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Wender Alves SilvaWender Alves Silva
Wender Alves Silva
CACarlos Kleber Z. Andrade
Carlos Kleber Z. Andrade
HNHamilton B. Napolitano
Hamilton B. Napolitano
IVIvo Vencato
Ivo Vencato
CLCarlito Lariucci
Carlito Lariucci
ACAdemir J. Camargo
Ademir J. Camargo

5 May 2014 in Beilstein Journal of Organic Chemistry
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Journal Article
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ABAngélica de Fátima S. Barreto
Angélica de Fátima S. Barreto
OVOtilie E Vercillo
Otilie E Vercillo
LWLudger A. Wessjohann
Ludger A. Wessjohann
CACarlos Kleber Z. Andrade
Carlos Kleber Z. Andrade
The synthesis of six cyclic depsipeptoids inspired by the natural depsipeptide sansalvamide A is described. An efficient and fast synthetic strategy was developed using a combination of consecutive isocyanide-based multicomponent reactions (Ugi and Passerini reactions). This methodology can be used to access a variety of cyclic oligodepsipeptoids.

15 April 2019 in Beilstein Journal of Organic Chemistry
Verified
Journal Article
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ABAngélica de Fátima S. Barreto
Angélica de Fátima S. Barreto
CACarlos Kleber Z. Andrade
Carlos Kleber Z. Andrade
Isocyanide-based multicomponent reactions are a versatile tool in the synthesis of heterocycles. This review describes recently developed approaches based on the combination of consecutive or repetitive isocyanide-based multicomponent reactions for the synthesis of structurally diverse heterocycles. These strategies have also allowed the synthesis of a plethora of macroheterocycles in a reduced number of steps.