Cardiovascular diseases (CVDs) are among the most impactful illnesses globally. Currently, the available therapeutic option has several side effects, including hypotension, bradycardia, arrhythmia, and alteration in different ion concentrations. Recently, bioactive compounds from natural sources, including plants, microorganisms, and marine creatures, have gained a lot of interest. Marine sources serve as reservoirs for new bioactive metabolites with various pharmacological activities. The marine-derived compound such as omega-3 acid ethyl esters, xyloketal B, asperlin, and saringosterol showed promising results in several CVDs. The present review focuses on marine-derived compounds’ cardioprotective potential for hypertension, ischemic heart disease, myocardial infarction, and atherosclerosis. In addition to therapeutic alternatives, the current use of marine-derived components, the future trajectory, and restrictions are also reviewed.

In the present study, multigrain fermented noodles were prepared using seera (fermented wheat starch), green gram, sorghum, and finger millet flours with different proportions. Then, the optimized formulation was developed, and cooking characteristics, sensory attributes, nutritional composition, and in vitro protein digestibility (IVPD) were evaluated. The prepared noodles showed better cooking characteristics, sensory attributes, and overall acceptability. Compared to commercial and control noodles, the optimized multigrain fermented noodles exhibited higher fiber, total phenol content, ash, iron, reducing sugar, and protein content. At the same time, the IVPD ( $92.5\pm 0.29\%$ ) of multigrain fermented noodles was comparable to control as well as commercial noodles. The XRD pattern showed a sharp peak at 15 and 20°, and the overall crystallinity was 34.12% observed. The ready-to-cook multigrain fermented noodles, prepared from the fermented wheat starch base, can be used as a healthy choice to refine wheat flour-based noodles, reducing chronic diseases.

Polycystic Ovary Syndrome (PCOS) is the primary endocrine disorder whose cause remains unidentified but is widely prevalent. This intricate condition affects a significant portion of women of reproductive age, affecting approximately 17.8% of them. While dietary approaches have been explored as the initial method of treatment for individuals with PCOS, there is no definitive consensus on the most effective diet. There is limited evidence to recommend a specific diet composition for PCOS with approaches including modifying protein, carbohydrate or fat quality or quantity generally having similar effects on the presentations of PCOS. It is crucial to recognize that maintaining a proper diet and ensuring sufficient nutritional status are pivotal factors in preventing the development of PCOS. In this comprehensive review, we explored various aspects of PCOS, ranging from its molecular pathogenesis to therapeutic dietary innovations and specific therapeutic interventions. Understanding the molecular pathogenesis of PCOS is vital, and we delve into the intricate mechanisms involved in its development. We examined the interplay between PCOS and metabolic conditions, such as insulin resistance and dyslipidemia, highlighting the interconnectedness of these aspects and their impact on the clinical presentation and management of the syndrome. While the optimal diet remains a subject of ongoing research, we emphasize on the critical role of proper diet and its potential in the avoidance and management of PCOS. Additionally, we reviewed specific dietary components, such as curcumin and green tea, and their potential therapeutic benefits in PCOS management.