In recent months, omicron (B.1.1.529) became the dominant variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), displaying some degree of immune evasion.
1 The initial omicron subvariants, BA.1 and BA.2, are being progressively displaced by BA.5 in many countries, possibly owing to greater transmissibility and partial evasion of BA.1- and BA.2-induced immunity.
2,3 The protection afforded by BA.1 against infection by the BA.5 subvariant is critical because adapted vaccines under clinical trials are based on BA.1.