Herein, we present a method for the quantitative analysis of broflanilide residues in water, soil, and rice samples from a paddy field in Jiangxi Province, China. The quick, easy, cheap, effective, rugged, and safe (QuEChERS) method was optimized for the extraction and purification of broflanilide residues. Residual broflanilide concentrations in different matrices were then determined by high-performance liquid chromatography (HPLC). The calibration curve of broflanilide showed good linearity in all matrices for concentrations between 0.005 and 1mg·L⁻¹, with a correlation coefficient greater than 0.99. The matrix effect varied from 69 to 54, indicating matrix suppression. The average recoveries ranged between 85.82 and 97.46, with relative standard deviations of 3.298.15. The limits of detection ranged from 0.16 to 1.67μg·kg⁻¹, and the limits of quantification were in the range of 0.54 to 5.48μg·kg⁻¹. Dissipation dynamic tests indicated broflanilide half-lives of 0.462.46, 2.095.34, and 1.313.32 days in soil, water, and rice straw, respectively. Broflanilide was dissipated more rapidly in water than in soil and rice straw. More than 90 of broflanilide residues dissipated within 14 days. The final residues of broflanilide in rice were all below LOQ at harvest.

In this study, the separation conditions of UHPLC-QTOF-MS and the extraction conditions of QuEChERS were optimized. The analytical process for determining Broflanilide residues in different soil types was successfully established and applied to its adsorption, desorption and leaching in soil. Broflanilide was extracted from soil with acetonitrile as extraction solvent, and purified with 50 mg PSA + 150 mg MgSO4. The modified UHPLC-QTOF-MS method was used for determination. In different types of soil, the average recovery of Broflanilide was 87.7% -94.38%, and the RSD was lower than 7.6%. In the analysis and determination of the adsorption, desorption and leaching properties in four soils, the RSD was less than 9.2%, showing good stability and can be applied to the analysis and determination of the residue of Broflanilide in different soils.