Ultrasound Localization Microscopy (ULM), an emerging medical imaging technique, effectively resolves the classical trade-off between resolution and penetration inherent in traditional ultrasound imaging, opening up new avenues for noninvasive observation of the microvascular system. However, traditional microbubble tracking methods encounter various practical challenges. These methods typically entail multiple processing stages, including intricate steps like pairwise correlation and trajectory optimization, rendering real-time applications unfeasible. Furthermore, existing deep learning-based tracking techniques neglect the temporal aspects of microbubble motion, leading to ineffective modeling of their dynamic behavior. To address these limitations, this study introduces a novel approach called the Gated Recurrent Unit (GRU)-based Multitasking Temporal Neural Network (GRU-MT). GRU-MT is designed to simultaneously handle microbubble trajectory tracking and trajectory optimization tasks. Additionally, we enhance the nonlinear motion model initially proposed by Piepenbrock et al. to better encapsulate the nonlinear motion characteristics of microbubbles, thereby improving trajectory tracking accuracy. In this study, we perform a series of experiments involving network layer substitutions to systematically evaluate the performance of various temporal neural networks, including Recurrent Neural Networks (RNN), Long Short-Term Memory (LSTM), GRU, Transformer, and its bidirectional counterparts, on the microbubble trajectory tracking task. Concurrently, the proposed method undergoes qualitative and quantitative comparisons with traditional microbubble tracking techniques. The experimental results demonstrate that GRU-MT exhibits superior nonlinear modeling capabilities and robustness, both in simulation and in vivo dataset. Additionally, it achieves reduced trajectory tracking errors in shorter time intervals, underscoring its potential for efficient microbubble trajectory tracking. Model code is open-sourced at https://github.com/zyt-Lib/GRU-MT.

Salient object detection aims to distinguish the most visually conspicuous regions, playing an important role in computer vision tasks. However, complex natural scenarios can challenge salient object detection, hindering accurate extraction of objects with rich morphological diversity. This paper proposes a novel method for salient object detection leveraging multi-visual perception, mirroring the human visual system’s rapid identification, and focusing on impressive objects/regions within complex scenes. First, a feature map is derived from the original image. Then, salient object detection results are obtained for each perception feature and combined via a feature fusion strategy to produce a saliency map. Finally, superpixel segmentation is employed for precise salient object extraction, removing interference areas. This multi-feature approach for salient object detection harnesses complementary features to adapt to complex scenarios. Competitive experiments on the MSRA10K and ECSSD datasets place our method in the first tier, achieving 0.1302 MAE and 0.9382 F-measure for the MSRA10K dataset and 0.0783 MAE and and 0.9635 F-measure for the ECSSD dataset, demonstrating superior salient object detection performance in complex natural scenarios.