The demand for artificial organs has greatly increased because of various aging-associated diseases and the wide need for organ transplants. A recent trend in tissue engineering is the precise reconstruction of tissues by the growth of cells adhering to bioscaffolds, which are three-dimensional (3D) structures that guide tissue and organ formation. Bioscaffolds used to fabricate bionic tissues should be able to not only guide cell growth but also regulate cell behaviors. Common regulation methods include biophysical and biochemical stimulations. Biophysical stimulation cues include matrix hardness, external stress and strain, surface topology, and electromagnetic field and concentration, whereas biochemical stimulation cues include growth factors, proteins, kinases, and magnetic nanoparticles. This review discusses bioink preparation, 3D bioprinting (including extrusion-based, inkjet, and ultraviolet-assisted 3D bioprinting), and regulation of cell behaviors. In particular, it provides an overview of state-of-the-art methods and devices for regulating cell growth and tissue formation and the effects of biophysical and biochemical stimulations on cell behaviors. In addition, the fabrication of bioscaffolds embedded with regulatory modules for biomimetic tissue preparation is explained. Finally, challenges in cell growth regulation and future research directions are presented.

Driven by the ever increasing demand in function integration, more and more next generation high value-added products, such as head-up displays, solar concentrators and intra-ocular-lens, etc., are designed to possess freeform (i.e., non-rotational symmetric) surfaces. The toolpath, composed of high density of short linear and circular segments, is generally used in computer numerical control (CNC) systems to machine those products. However, the discontinuity between toolpath segments leads to high-frequency fluctuation of feedrate and acceleration, which will decrease the machining efficiency and product surface finish. Driven by the ever-increasing need for high-speed high-precision machining of those products, many novel toolpath interpolation and smoothing approaches have been proposed in both academia and industry, aiming to alleviate the issues caused by the conventional toolpath representation and interpolation methods. This paper provides a comprehensive review of the state-of-the-art toolpath interpolation and smoothing approaches with systematic classifications. The advantages and disadvantages of these approaches are discussed. Possible future research directions are also offered.

This study presents laser stripe center extraction algorithm for desktop-level 3D laser scanners. The laser stripe center extraction accuracy is an important factor affecting 3D scanning result. Desktop-level devices should have adaptability of a wide range of scanning objects. In this paper, laser stripe energy distribution characteristics with different laser stripe width, ambient light, materials and colors are obtained by experiments. Experiment results show that waveforms of bright spot, low brightness stripe and stripe with large width are complex or easily disturbed, so the center extraction algorithm of them are studied. The extraction effects of extremum method, gradient method and gray centroid method under different conditions are compared. Based on traditional grayscale value, a weighted grayscale value is proposed to extract laser stripe center. Standard deviations of extracted pixel position and fitting pixel position are calculated by different method with different weighted grayscale value. For different conditions, especially for different ambient light intensity, weight matrix plays an important role to extraction result.

Flexible piezoelectric nanogenerators (PENGs) used in body movement real-time monitoring are of great interest for their wide application potential such as in the field of smart healthcare. In this work, a self-powered BaTiO₃/Polydimethylsiloxane (PDMS) PENG for body movement sensing was successfully fabricated by extrusion 3D printing. Matrix system composed of different ratios of PDMS was selected based on the rheological property of materials. Experimental investigations were conducted to examine the impact of printing pressure and speed on the linewidth. Subsequently, the extrusion parameters for nanogenerators were determined based on the printed linewidth. The composite showed good ferroelectric property. After polarization, the nanogenerators exhibited an improvement in output performance of up to 55.2%. Additionally, the device demonstrated a good linear relationship between voltage and tapped force test by an electromechanical vibrator. Successful detection of body or muscle movement signals was achieved when the nanogenerator was mounted on the human finger, throat, or foot using a wearable sock, highlighting its potential for applications in self-powered wearable devices for smart healthcare.