Flexographic printing is a highly sought-after technique within the realm of packaging and labeling due to its versatility, cost-effectiveness, high speed, high-quality images, and environmentally friendly nature. A major challenge in flexographic printing is the need to optimize energy usage, which requires diligent attention to resolve. This research combines lean principles and machine learning to improve energy efficiency in selected flexographic printing machines; i.e., Miraflex and F&K. By implementing the 5Why root cause analysis and Kaizen, the study found that the idle time was reduced by 30% for the Miraflex machine and the F&K machine, resulting in energy savings of 34.198% and 38.635% per meter, respectively. Additionally, a multi-linear regression model was developed using machine learning and a range of input parameters, such as machine speed, production meter, substrate density, machine idle time, machine working time, and total machine run time, to predict energy consumption and optimize job scheduling. The results of the research exhibit that the model was efficient and accurate, leading to a reduction in energy consumption and costs while maintaining or even improving the quality of the printed output. This approach can also add to reducing the carbon footprint of the manufacturing process and help companies meet sustainability goals.

The exponential rise of healthcare problems like human aging and road traffic accidents have developed an intrinsic challenge to biomedical sectors concerning the arrangement of patient-specific biomedical products. The additively manufactured implants and scaffolds have captured global attention over the last two decades concerning their printing quality and ease of manufacturing. However, the inherent challenges associated with additive manufacturing (AM) technologies, namely process selection, level of complexity, printing speed, resolution, biomaterial choice, and consumed energy, still pose several limitations on their use. Recently, the whole world has faced severe supply chain disruptions of personal protective equipment and basic medical facilities due to a respiratory disease known as the coronavirus (COVID-19). In this regard, local and global AM manufacturers have printed biomedical products to level the supply–demand equation. The potential of AM technologies for biomedical applications before, during, and post-COVID-19 pandemic alongwith its relation to the industry 4.0 (I4.0) concept is discussed herein. Moreover, additive manufacturing technologies are studied in this work concerning their working principle, classification, materials, processing variables, output responses, merits, challenges, and biomedical applications. Different factors affecting the sustainable performance in AM for biomedical applications are discussed with more focus on the comparative examination of consumed energy to determine which process is more sustainable. The recent advancements in the field like 4D printing and 5D printing are useful for the successful implementation of I4.0 to combat any future pandemic scenario. The potential of hybrid printing, multi-materials printing, and printing with smart materials, has been identified as hot research areas to produce scaffolds and implants in regenerative medicine, tissue engineering, and orthopedic implants.

The goal of this research is to develop a novel second-generation-based biogas supply chain network design (BG-SCND) model that takes into account the triple bottom line approach. Biogas is a promising renewable energy source that can be obtained from a variety of easily accessible second-generation wastes, including animal manure, municipal waste, and agricultural leftovers. Integrated optimization of the biogas generation system is essential for a speedy and environmentally friendly transition to sustainable biodiesel production. The dynamic environment of the energy market significantly impairs the decisions of the BG-SCND model; therefore, a hybrid solution approach using flexible programming and possibilistic programming is suggested. To verify the suggested model and approach for solving the problem, a thorough computational analysis of a case study is conducted. The case study findings demonstrate that considerable investment is necessary to attain social and environmental well-being goals and safeguard decisions against epistemic uncertainty. Policymakers involved in the planning of biogas production and distribution projects may find the proposed approach useful.

This investigation delves into the effectiveness of employing vegetable-based cutting fluids and nanoparticles in milling AZ31 magnesium alloy, as part of the pursuit of ecologically sustainable manufacturing practices. The study scrutinizes three different cutting environments: (i) dry cutting; (ii) minimum quantity lubrication (MQL) with rice bran oil as the base oil and turmeric oil as an additive; and (iii) MQL with rice bran oil as the base oil, and turmeric oil and kaolinite nanoparticles as additives. Fuzzy logic was implemented to develop the design of experiments and assess the impact of these cutting environments on carbon emissions, surface quality, and microhardness. Upon conducting an analysis of variance (ANOVA), it was determined that all the three input parameters (cutting environment, cutting speed, and feed) greatly affect carbon emissions. The third cutting environment (MQL + bio-oils + kaolinite) generated the lowest carbon emissions (average of 9.21 ppm) and surface roughness value (0.3 um). Confirmatory tests validated that the output parameters predicted using the multiobjective genetic algorithm aligned well with experimental values, thus affirming the algorithm’s robustness.