Delia Hernández-Romero

Dr. Delia Hernández-Romero


Research Focus & Metrics

Academic Career Length

5Years (2022-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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23 September 2022 in ChemMedChem
Verified
Journal Article
Open access
LALuis A. Alfonso‐Herrera
Luis A. Alfonso‐Herrera
SLSharon Rosete Luna
Sharon Rosete Luna
DHDelia Hernández-Romero
Delia Hernández-Romero
JRJosé M. Rivera‐Villanueva
José M. Rivera‐Villanueva
JOJosé Luis Olivares-Romero
José Luis Olivares-Romero
RCRaúl Colorado-Peralta
Raúl Colorado-Peralta
Although it is known that the first case of cancer was recorded in ancient Egypt around 1600 BC, it was not until 1917 during the First World War and the development of mustard gas that chemotherapy against cancer became relevant; however, its properties were not recognised until 1946 to later be used in patients. In this sense, the use of metallopharmaceuticals in cancer therapy was extensively explored until the 1960s with the discovery of cisplatin and its anticancer activity. From that date to the present, the search for more effective, more selective metallodrugs with fewer side effects has been an area of continuous exploration. Efforts have led to considering a wide variety of metals from the periodic table, mainly from the d‐block, as well as a wide variety of organic ligands, preferably with proven biological activity. In this sense, various research groups have found an ideal binder in Schiff bases, since their raw materials are easily accessible, their synthesis conditions are friendly and their denticity can be manipulated. Therefore, in this review, we have explored the anticancer and antitumor activity reported in the literature for coordination complexes of d‐block metals coordinated with tridentate Schiff bases (O N O and O N N) derived from salicylaldehyde. For this work, we have used the main scientific databases CCDC® and SciFinder®.

25 April 2023 in Inorganics
Verified
Journal Article
Open access
PDF file
RCRaúl Colorado-Peralta
Raúl Colorado-Peralta
JOJosé Luis Olivares-Romero
José Luis Olivares-Romero
SLSharon Rosete Luna
Sharon Rosete Luna
Oscar García-BarradasOscar García-Barradas
Oscar García-Barradas
VIVIANA REYES MARQUEZVIVIANA REYES MARQUEZ
VIVIANA REYES MARQUEZ
DAVID MORALES-MORALESDAVID MORALES-MORALES
DAVID MORALES-MORALES
Throughout human history, bacteria and fungi have caused infections that are difficult to combat. For this reason, countless research groups have developed novel compounds to solve this problem. Thiazole and benzothiazole are present in different structures with interesting biological effects and are used to develop new effective antimicrobial agents. Moreover, nitrogen atoms that are present in this heterocycle allow for coordination with various metals, forming metal complexes that enhance the biological activity of organic ligands that are often used as commercial drugs. This bibliographical review summarizes the copper complexes that use thiazole and benzothiazole as ligands and that report efficient antimicrobial activity against different bacteria and fungi.

1 November 2025 in Reactions
Verified
Journal Article
Open access
PDF file
LALuis Pablo Amador-Gómez
Luis Pablo Amador-Gómez
DHDelia Hernández-Romero
Delia Hernández-Romero
JRJose Rivera
Jose Rivera
SLSharon Rosete Luna
Sharon Rosete Luna
CCCarlos Alberto Cruz Cruz
Carlos Alberto Cruz Cruz
RCRaúl Colorado-Peralta
Raúl Colorado-Peralta
Biodiesel is an alternative, sustainable, renewable, and environmentally friendly energy source, which has generated interest from the scientific community due to its low toxicity, rapid biodegradability, and zero carbon footprint. Biodiesel is a biofuel produced by the transesterification of triglycerides or the esterification of free fatty acids (FFA). Both reactions require catalysts with numerous active sites (basic, acidic, bifunctional, or enzymatic) for efficient biodiesel production. On the other hand, since the late 1990s, metal–organic frameworks (MOFs) have emerged as a new class of porous materials and have been successfully used in various fields due to their multiple properties. For this reason, MOFs have been used as heterogeneous catalysts or as a platform for designing active sites, thus improving stability and reusability. This literature review presents a comprehensive analysis of using MOFs as heterogeneous catalysts or supports for biodiesel production. The optimal parameters for transesterification/esterification are detailed, such as the alcohol/feedstock molar ratio, catalyst amount, reaction time and temperature, conversion percentage, biodiesel yield, fatty acid and water content, etc. Additionally, novel methodologies such as ultrasound and microwave irradiation for obtaining MOF-based catalysts are described. It is important to note that most studies have shown biodiesel yields >90% and multiple reuse cycles with minimal activity loss. The bibliographic analysis was conducted using the American Chemical Society (ACS) Scifinder® database, the Elsevier B.V. Scopus® database, and the Clarivate Analytics Web of Science® database, under the institutional license of the Universidad Veracruzana. Keywords were searched for each section, generally limiting the document type to “reviews” and “journals,” and the language to English, and published between 2000 and 2025.

24 November 2024 in Reactions
Verified
Journal Article
Open access
PDF file
DHDelia Hernández-Romero
Delia Hernández-Romero
SLSharon Rosete Luna
Sharon Rosete Luna
EBEnrique Méndez Bolaina
Enrique Méndez Bolaina
ECElena de la C. Herrera Cogco
Elena de la C. Herrera Cogco
LALuis Pablo Amador-Gómez
Luis Pablo Amador-Gómez
RCRaúl Colorado-Peralta
Raúl Colorado-Peralta
Despite multiple advances in treatment and prevention, cancer remains one of the leading causes of death worldwide. Chemotherapy remains the most effective method for cancer treatment. However, commercial chemotherapeutic drugs have limited efficacy, severe side effects, and acquired resistance. Therefore, the scientific community has devoted a great effort to designing new, more effective, and cheaper drugs. In this sense, copper-catalyzed azide-alkyne cycloaddition reactions (CuAAC) provide 1,4-disubstituted 1H-1,2,3-triazoles in high yields without forming by-products. This reaction allows the easy, efficient, functional, ordered, rapid, selective, and specific joining of small molecules, giving rise to more complex molecules. The CuACC reaction simplifies the synthesis processes, accelerating the discovery of new chemotherapeutic agents by allowing the joining of commercial platinum drugs, slightly altering their structure, or creating new molecules with improved properties. This work shows the importance of CuAAC reactions in the search for new metallodrugs with possible anticancer activity.

13 April 2022 in European Journal of Integrative Medicine
Verified
Journal Article
Closed access
OSOscar Antonio Sánchez-Aguirre
Oscar Antonio Sánchez-Aguirre
EJEnrique Juárez-Aguilar
Enrique Juárez-Aguilar
EMEva Luz Montoya-Hernández
Eva Luz Montoya-Hernández
MVMaribel Vázquez-Hernández
Maribel Vázquez-Hernández
RCRaúl Colorado-Peralta
Raúl Colorado-Peralta
DHDelia Hernández-Romero
Delia Hernández-Romero

1 March 2024 in Noviembre-Diciembre 2022
Verified
Journal Article
Open access
PDF file
SRSharon Rosete-Luna
Sharon Rosete-Luna
DHDelia Hernández-Romero
Delia Hernández-Romero
Todos sabemos que a diario utilizamos compuestos químicos de una u otra forma, incluso que son parte de nuestro cuerpo, sin embargo, nos es difícil reconocer algunos fragmentos importantes de éstos. Por lo que la finalidad de este artículo es dar a conocer ciertos grupos funcionales presentes en las estructuras químicas, ya que este pequeño cambio en la estructura permite que tengan diferentes características y por lo tanto innumerables usos en nuestra vida diaria.