Líliam César de Castro Medeiros

Dr. Líliam César de Castro Medeiros

orcid

Research Focus & Metrics

Academic Career Length

16Years (2011-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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11 January 2011 in PLOS Neglected Tropical Diseases
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LMLíliam César de Castro Medeiros
Líliam César de Castro Medeiros
CCCésar Augusto Rodrigues Castilho
César Augusto Rodrigues Castilho
CBCYNTHIA BRAGA
CYNTHIA BRAGA
WSWayner Vieira De Souza
Wayner Vieira De Souza
LRLeda Regis
Leda Regis
AMAntonio Miguel Vieira Monteiro
Antonio Miguel Vieira Monteiro
Dengue is a disease of great complexity, due to interactions between humans, mosquitoes and various virus serotypes as well as efficient vector survival strategies. Thus, understanding the factors influencing the persistence of the disease has been a challenge for scientists and policy makers. The aim of this study is to investigate the influence of various factors related to humans and vectors in the maintenance of viral transmission during extended periods. We developed a stochastic cellular automata model to simulate the spread of dengue fever in a dense community. Each cell can correspond to a built area, and human and mosquito populations are individually monitored during the simulations. Human mobility and renewal, as well as vector infestation, are taken into consideration. To investigate the factors influencing the maintenance of viral circulation, two sets of simulations were performed: (1st) varying human renewal rates and human population sizes and (2nd) varying the house index (fraction of infested buildings) and vector per human ratio. We found that viral transmission is inhibited with the combination of small human populations with low renewal rates. It is also shown that maintenance of viral circulation for extended periods is possible at low values of house index. Based on the results of the model and on a study conducted in the city of Recife, Brazil, which associates vector infestation with Aedes aegytpi egg counts, we question the current methodology used in calculating the house index, based on larval survey. This study contributed to a better understanding of the dynamics of dengue subsistence. Using basic concepts of metapopulations, we concluded that low infestation rates in a few neighborhoods ensure the persistence of dengue in large cities and suggested that better strategies should be implemented to obtain measures of house index values, in order to improve the dengue monitoring and control system. Dengue is the most rapidly spreading mosquito-borne viral disease in the world and approximately 2.5 billion people live in dengue endemic countries. In Brazil it is mainly transmitted by Aedes aegypti mosquitoes. The wide clinical spectrum ranges from asymptomatic infections or mild illness, to the more severe forms of infection such as dengue hemorrhagic fever or dengue shock syndrome. The spread and dramatic increase in the occurrence of dengue cases in tropical and subtropical countries has been blamed on uncontrolled urbanization, population growth and international traveling. Vaccines are under development and the only current disease control strategy is trying to keep the vector quantity at the lowest possible levels. Mathematical models have been developed to help understand the disease's epidemiology. These models aim not only to predict epidemics but also to expand the capacity of phenomena explanation. We developed a spatially explicit model to simulate the dengue transmission in a densely populated area. The model involves the dynamic interactions between humans and mosquitoes and takes into account human mobility as an important factor of disease spread. We investigated the importance of human population size, human renewal rate, household infestation and ratio of vectors per person in the maintenance of sustained viral circulation.

3 July 2013 in PLOS ONE
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LRLêda N. Regis
Lêda N. Regis
RARidelane Veiga Acioli
Ridelane Veiga Acioli
JSJosé Constantino Silveira
José Constantino Silveira
MMMaria Alice Varjal Melo-Santos
Maria Alice Varjal Melo-Santos
WSWayner Vieira Souza
Wayner Vieira Souza
AFAndré Freire Furtado
André Freire Furtado
Aedes aegypti has developed evolution-driven adaptations for surviving in the domestic human habitat. Several trap models have been designed considering these strategies and tested for monitoring this efficient vector of Dengue. Here, we report a real-scale evaluation of a system for monitoring and controlling mosquito populations based on egg sampling coupled with geographic information systems technology. The SMCP-Aedes, a system based on open technology and open data standards, was set up from March/2008 to October/2011 as a pilot trial in two sites of Pernambuco -Brazil: Ipojuca (10,000 residents) and Santa Cruz (83,000), in a joint effort of health authorities and staff, and a network of scientists providing scientific support. A widespread infestation by Aedes was found in both sites in 2008–2009, with 96.8%–100% trap positivity. Egg densities were markedly higher in SCC than in Ipojuca. A 90% decrease in egg density was recorded in SCC after two years of sustained control pressure imposed by suppression of >7,500,000 eggs and >3,200 adults, plus larval control by adding fishes to cisterns. In Ipojuca, 1.1 million mosquito eggs were suppressed and a 77% reduction in egg density was achieved. This study aimed at assessing the applicability of a system using GIS and spatial statistic analysis tools for quantitative assessment of mosquito populations. It also provided useful information on the requirements for reducing well-established mosquito populations. Results from two cities led us to conclude that the success in markedly reducing an Aedes population required the appropriate choice of control measures for sustained mass elimination guided by a user-friendly mosquito surveillance system. The system was able to support interventional decisions and to assess the program’s success. Additionally, it created a stimulating environment for health staff and residents, which had a positive impact on their commitment to the dengue control program.

23 August 2022 in Sustainability
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Adriano BressaneAdriano Bressane
Adriano Bressane
Rogério Galante NegriRogério Galante Negri
Rogério Galante Negri
IJIrineu Brito Junior
Irineu Brito Junior
LMLíliam César de Castro Medeiros
Líliam César de Castro Medeiros
IAIsabela Lopes Lima Araújo
Isabela Lopes Lima Araújo
GRGraziele Coraline Scofano da Rosa
Graziele Coraline Scofano da Rosa
Mental health benefits have been linked to human interaction with nature. However, most studies have been carried out in developed countries, limiting the generalizability of empirical findings to other parts of the world. To address this gap, this study was conducted in Brazil. The objective of the study was to assess whether the frequency of contact with nature affects the occurrence of anxiety, stress, and depression. Data were collected between June and July 2022 through an online survey (n = 1186, 1 − α = 0.95, p = 0.05, 1 − β = 0.85, rho = 0.1). Thus, the public online survey made it possible to carry out voluntary response sampling suitable for an exploratory study, with the purpose of an initial understanding of an under-researched population. First, a logistic regression was performed for quantifying the association between contact with nature and mental symptoms. In addition, three groups of people having different frequencies (low, medium, and high) of contact with nature and a reference group, comprised of those who reported no contact, were compared using Kruskal–Wallis and Dwass–Steel–Chritchlow–Fligner tests. This study employs a cross-sectional design and relies on retrospective recall. As a result, the research hypothesis was confirmed. People who very rarely have contact with nature had a 97.95% probability of moderate occurrence of stress, which decreases to 20.98% for people who have contact with nature frequently. Furthermore, in the same comparison, the probability of occurrence was 3.6 times lower for anxiety and 4.8 times lower for depression. In conclusion, the evidence indicates that the greater the frequency of contact with nature, the lower the occurrence of stress, anxiety, and depression symptoms. Nevertheless, the benefits of this contact were significant only when its frequency was moderate (about once or twice a week) or higher.

TLTiago França Melo De Lima
Tiago França Melo De Lima
RLRaquel Martins Lana
Raquel Martins Lana
TCTiago Garcia De Senna Carneiro
Tiago Garcia De Senna Carneiro
CCCláudia Torres Codeço
Cláudia Torres Codeço
GMGabriel Machado
Gabriel Machado
CDClodoveu Davis
Clodoveu Davis
The prevention and control of dengue are great public health challenges for many countries, particularly since 2015, as other arboviruses have been observed to interact significantly with dengue virus. Different approaches and methodologies have been proposed and discussed by the research community. An important tool widely used is modeling and simulation, which help us to understand epidemic dynamics and create scenarios to support planning and decision making processes. With this aim, we proposed and developed DengueME, a collaborative open source platform to simulate dengue disease and its vector’s dynamics. It supports compartmental and individual-based models, implemented over a GIS database, that represent Aedes aegypti population dynamics, human demography, human mobility, urban landscape and dengue transmission mediated by human and mosquito encounters. A user-friendly graphical interface was developed to facilitate model configuration and data input, and a library of models was developed to support teaching-learning activities. DengueME was applied in study cases and evaluated by specialists. Other improvements will be made in future work, to enhance its extensibility and usability.

Adriano BressaneAdriano Bressane
Adriano Bressane
MSMirela Beatriz Silva
Mirela Beatriz Silva
AGAna Paula Garcia Goulart
Ana Paula Garcia Goulart
LMLíliam César de Castro Medeiros
Líliam César de Castro Medeiros
Statement of problem: Urbanization has brought significant advancements in human well-being; however, it poses challenges to urban green spaces (UGSs), affecting environmental quality and public health. Research gap: Previous studies have established the importance of UGSs for urban well-being but have not sufficiently explored how the naturalness of these spaces—ranging from untouched natural areas to human-designed landscapes—affects mental health outcomes in the context of developing countries, particularly Brazil. Purpose: This study aimed to bridge the research gap by investigating the relationship between the degree of naturalness in UGSs and mental health among residents of Brazilian metropolitan areas. Method: Data were collected through an online survey involving 2136 respondents from various Brazilian urban regions. The study used Welch’s ANOVA and Games–Howell post hoc tests to analyze the impact of UGS naturalness on mental health, considering depression, anxiety, and stress levels. Results and conclusions: The findings revealed that higher degrees of naturalness in UGSs significantly correlate with lower levels of mental distress. These results underscore the necessity of integrating natural elements into urban planning to enhance public health. Practical implications: Urban planners and policymakers are encouraged to prioritize the preservation and creation of naturalistic UGSs in urban environments to improve mental health outcomes. Future directions: Further research should explore the specific attributes of naturalness that most contribute to well-being and examine the scalability of these findings across different cultural and environmental contexts.

28 October 2022 in Sustainability
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Adriano BressaneAdriano Bressane
Adriano Bressane
MSMarianne Spalding
Marianne Spalding
DZDaniel Zwirn
Daniel Zwirn
ALAnna Isabel Silva Loureiro
Anna Isabel Silva Loureiro
Abayomi Oluwatobiloba BankoleAbayomi Oluwatobiloba Bankole
Abayomi Oluwatobiloba Bankole
RODRIGO MORUZZIRODRIGO MORUZZI
RODRIGO MORUZZI
Understanding the key factors that play an important role in students’ performance can assist improvements in the teaching-learning process. As an alternative, artificial intelligence (AI) methods have enormous potential, facilitating a new trend in education. Despite the advances, there is an open debate on the most suitable model for machine learning applied to forecast student performance patterns. This paper addresses this gap, where a comparative analysis between AI methods was performed. As a research hypothesis, a fuzzy inference system (FIS) should provide the best accuracy in this forecast task, due to its ability to deal with uncertainties. To do so, this paper introduces a model proposal based on AI using a FIS. An online survey was carried to collect data. Filling out a self-report, respondents declare how often they use some learning strategies. In addition, we also used historical records of students’ grades and retention from the last 5 years before the COVID pandemic. Firstly, two experimental groups were composed of students with failing and passing grades, compared by the Mann-Whitney test. Secondly, an association between the ‘frequency of using learning strategies’ and ‘occurrence of failing grades’ was quantified using a logistic regression model. Then, a discriminant analysis was performed to build an Index of Student Performance Expectation (SPE). Considering the learning strategies with greater discriminating power, the fuzzy AI-based model was built using the database of historical records. The learning strategies with the most significant effect on students’ performance were lesson review (34.6%), bibliography reading (25.6%), class attendance (23.5%), and emotion control (16.3%). The fuzzy AI-based model proposal outperformed other AI methods, achieving 94.0% accuracy during training and a generalization capacity of 91.9% over the testing dataset. As a practical implication, the SPE index can be applied as a tool to support students’ planning in relation to the use of learning strategies. In turn, the AI model based on fuzzy can assist professors in identifying students at higher risk of retention, enabling preventive interventions.