Since carbon quantum dots have high photoluminescent efficiency, it has been a desired material in sensor and bioimaging applications. In recent years, the green chemistry approach has been preferred and the production of quantum dots has been reported in many studies using different precursors from natural, abundant, or waste sources. Hydrothermal, chemical oxidation, microwave supported, ultrasonic, solvothermal, pyrolysis, laser etching, solid-state, plasma, and electrochemical methods have been reported in the literature. In this review article, green chemistry strategies for carbon quantum dot synthesis is summarized and compared with conventional methods using methodologic and statistical data. Furthermore, a detailed discussion on sensor and bioimaging applications of carbon quantum dots produced with green synthesis approaches are presented with a special focus on the last decade. Graphical Abstract

Zearalenone (ZEN) is a toxic compound produced by the metabolism of fungi (genus Fusarium) that threaten the food and agricultural industry belonging to the in foods and feeds. ZEN has toxic effects on human and animal health due to its mutagenicity, teratogenicity, carcinogenicity, nephrotoxicity, immunotoxicity, and genotoxicity. To ensure food safety, rapid, precise, and reliable analytical methods can be developed for the detection of toxins such as ZEN. Different selective molecular diagnostic elements are used in conjunction with different detection strategies to achieve this goal. In this review, the use of electrochemical, colorimetric, fluorometric, refractometric as well as other strategies were discussed for ZEN detection. The success of the sensors in analytical performance depends on the development of receptors with increased affinity to the target. This requirement has been met with different immunoassays, aptamer-assays, and molecular imprinting techniques. The immobilization techniques and analysis strategies developed with the combination of nanomaterials provided high precision, reliability, and convenience in ZEN detection, in which electrochemical strategies perform the best.