With the wide usage of organic compounds, the assessment of their acute toxicity has drawn great attention to reduce animal testing and human labor. The development of graph models provides new opportunities for acute toxicity prediction. In this study, five graph models (message-passing neural network, graph convolution network, graph attention network, path-augmented graph transformer network, and Attentive FP) were applied on four toxicity tasks (fish, Daphnia magna, Tetrahymena pyriformis, and Vibrio fischeri). With the lowest prediction error, Attentive FP was reported to have the best performance in all four tasks. Moreover, the attention weights of the Attentive FP model helped to construct atomic heatmaps and provide good explainability.

An in situ labelling strategy was proposed to produce quantum dot-labelled respiratory syncytial viruses (RSVs) by incorporating the biotinylated membrane protein of the host cells into mature virions, followed by conjugation with streptavidin modified quantum dots (SA-QDs), which has the advantages such as convenience, efficiency and minor influence on viral infectivity and thus could be successfully applied to track the early stage of virus entry.

Full-solution processed and all-inorganic electroluminescent devices are regarded as a promising technology for high-resolution displays and solid-state lighting due to their low-cost and air stable properties. In this work, hole transport layer-free and full-solution processed all-inorganic quantum dot light emitting diodes (QD-LEDs) were fabricated successfully. We employed a simplified device architecture of glass/ITO/Mg(OH)2 (2 nm)/QDs (18 nm)/ZnO (75 nm)/Al (100 nm) and utilized insulating Mg(OH)2 layer to balance the electron and hole charge transportation. All of the device fabrication procedures were carried out in ambient condition except for thermally evaporating and the completed QD-LEDs were measured in the open air without any encapsulation. A maximum luminance of 2930 cd/m2 and current efficiency of 1.08 cd/A were obtained with a low turn-on voltage of 1.6 V.