Low back pain is one of the main causes of motor disabilities and psychological stress, with the painful process encompassing sensory and affective components. Noxious stimuli originate on the periphery; however, the stimuli are recombined in the brain and therefore processed differently due to the emotional environment. To better understand this process, our objective was to develop a mathematical representation of the International Association for the Study of Pain (IASP) model of pain, covering the multidimensional representation of this phenomenon. Data from the Oswestry disability index; the short form of the depression, anxiety, and stress scale; and pain catastrophizing daily questionnaires were collected through online completion, available from 8 June 2022, to 8 April 2023 (1021 cases). Using the information collected, an artificial neural network structure was trained (based on anomaly detection methods) to identify the patterns that emerge from the relationship between the variables. The developed model proved to be robust and able to show the patterns and the relationship between the variables, and it allowed for differentiating the groups with altered patterns in the context of low back pain. The distinct groups all behave according to the main finding that psychological and pain events are directly associated. We conclude that our proposal is effective as it is able to test and confirm the definition of the IASP for the study of pain. Here we show that the fiscal and mental dimensions of pain are directly associated, meaning that mental illness can be an enhancer of pain episodes and functionality.

Falls, a major cause of injury and disability, particularly among older adults, present a significant public-health challenge. Existing methods of balance assessment often lack the sensitivity and specificity needed to identify subtle deviations from normal patterns, hindering early intervention. To address this gap, we introduced a novel artificial intelligence-based tool that leverages anomaly detection to provide a comprehensive assessment of balance performance across all age groups. This study evaluated the tool’s effectiveness in 163 individuals aged 18–85 years who were assessed using a force platform under four conditions: eyes open and eyes closed on firm and foam surfaces. Data analysis, employing an artificial neural network with 19 socio-anthropometric and postural variables, showed the tool’s exceptional accuracy (R = 0.99998) in differentiating among balance profiles. Notably, the model highlighted the significant impact of age and education on balance, with older adults demonstrating increased reliance on visual input, especially when somatosensory information was reduced on foam surfaces. In contrast, younger, more educated individuals exhibited a more integrated sensorimotor approach. These findings demonstrate that our anomaly-detection tool can identify subtle balance impairments often missed by traditional methods, offering valuable insights for personalized fall-risk assessment and intervention. This AI-based approach can provide a holistic assessment of balance, leading to more effective strategies for fall prevention and rehabilitation, particularly in aging populations.