The importance of network security has increased with the emergence of networked systems in contemporary computing, making it an essential aspect of protecting digital assets and safeguarding against cyber threats. The current security mechanisms, which rely on cryptographic keys, may be susceptible to a number of attacks, such as media access control (MAC) spoofing, which might provide unauthorized users access to network resources. This study introduces a new approach, namely a zero-trust security framework with quantum fingerprinting for devices accessing a network, that utilizes quantum technology to protect networks from security threats and intruders. The proposed architecture relies on quantum fingerprinting to authenticate devices trying to access the network, and it is built on the zero-trust security concept. The framework is intended to offer a thorough, multi-layered approach to network security that may change in response to evolving security risks and specifications. By protecting against MAC spoofing and other types of device impersonation, the adoption of quantum fingerprinting adds another degree of protection. The proposed framework may be used to construct a reliable and scalable network security solution in different network environments.