Cutaneous syncytial myoepithelioma (CSM) is a rare type of cutaneous neoplasm that typically presents as a solitary and well-circumscribed nodule on the skin. It predominantly occurs on the upper and lower extremities of adult patients. Immunohistochemically, CSM is characterized by the co-expression of smooth muscle and epithelial markers. Fluorescence in situ hybridization (FISH) targeting the EWSR1 gene rearrangement is an important diagnostic tool for CSM. In our case report, we found the focal positivity for CD34, which has never been previously observed; this was mostly confined to a central area of the neoplasm.

Citation: Gualdi G, Ariasi C, Amerio P, Galdo G, Calzavara-Pinton P, Licata G. Inflammatory Linear Verrucous Epidermal Nevus Assessment With in Vivo Reflectance Confocal Microscopy: An Easy Option to Consider. Dermatol Pract Concept. 2023;13(2):e2023107. DOI: https://doi.org/10.5826/dpc.1302a107 Accepted: October 21, 2023; Published: April 2023 Copyright: ©2023 Gualdi et al. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (BY-NC-4.0), https://creativecommons.org/licenses/by-nc/4.0/, which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original authors and source are credited. Funding: None. Competing interests: None. Authorship: All authors have contributed significantly to this publication. Corresponding author: Gaetano Licata, MD, Department of Dermatology, University of Brescia, ASST Spedali Civili di Brescia, P.le Spedali Civili 1, 25123, Brescia, Italy. Phone: +393276215976 E-mail gaetano.licata89@gmail.com Keywords : inflammatory linear verrucous epidermal nevus, confocal microcopy, child, non-invasive technology This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.