Background: Urinary tract infections (UTIs) are a prevalent form of urinary tract diseases affecting individuals of all ages and genders. In the Kingdom of Saudi Arabia (KSA), UTIs are a significant burden on the healthcare system, comprising 10% of all infections and ranking as the second leading cause of emergency department admissions. Despite this, limited research has been conducted in Saudi Arabia, particularly in Jazan Province, located in the southwestern region. Methods: This retrospective, cross-sectional study encompassed individuals with positive urine cultures who sought care at a tertiary hospital in Jazan between January 2022 and March 2023. A standardized data collection form was utilized to retrieve relevant information from microbiology lab test results and patients’ electronic medical records. Variables such as sex, urine sample collection date, bacterial isolates, antibiotic sensitivity, and resistance were collected using the data collection form. Data were analyzed using SPSS software, version 23.0 (IBM Corp., Armonk, NY, USA). Results: A total of 1082 urinary bacterial samples were isolated and identified. Females accounted for more bacterial infections (62.66%) than males (37.34%). Gram-negative bacteria represented 94% of all isolated strains. The most prevalent pathogens associated with UTIs were Escherichia coli (47.97%), Klebsiella pneumoniae (24.58%), and Pseudomonas aeruginosa (11.55%). Antimicrobial resistance patterns indicated the presence of extended-spectrum beta-lactamase (ESBL) (30.13%), carbapenemase-resistant Enterobacter (CRE) (1.94%), methicillin-resistant Staphylococcus aureus (MRSA) (0.74%), and vancomycin-resistant Enterococci (VRE) (0.18%). UTI incidence demonstrated a higher prevalence in September (13%) compared to other months in 2022. Escherichia coli, Klebsiella pneumoniae, and Pseudomonas aeruginosa were the predominant Gram-negative multidrug-resistant organisms (MDRO), accounting for 34.42%, 13.95%, and 1.63% of the population. Conclusions: The prevalence of UTIs caused by antibiotic-resistant microbes is notable in Jazan. Consistent with findings from other regions, Escherichia coli remains the most common causative pathogen of UTIs, displaying a seasonal pattern that warrants attention. Approximately 35% of reported cases involve MDRO, with ESBLs accounting for 30%. These results should raise concerns among healthcare officials, highlighting the necessity for further investigations into factors contributing to the circulation of MDRO in Jazan.

Caffeine is a central nervous system stimulant. High consumption levels of caffeine can lead to intoxication and serious side effects. Saudi Arabia is witnessing a rise in the commercialization and consumption of caffeine. Young adults such as university students may exhibit high levels of caffeine consumption. This investigation aims to assess caffeine consumption habits among a sample of Jazan University students in the south of Saudi Arabia. This study was a cross-sectional investigation that utilized multistage sampling to recruit the students. Data was collected via a self-administered questionnaire that measured student demographics, their frequency of consuming caffeine-containing food, portion sizes, and patterns of consumption during different times of the day. Caffeine consumption levels were estimated based on a cutoff point of 400 mg per day. A chi-squared test was used to investigate the association between levels of caffeine consumption and measured study characteristics. A sample of 964 students was recruited with a mean age of 21.8 years. The most frequently consumed product among the recruited students was coffee (32%), followed by chocolate bars (16%) and soft drinks (12%). The median total consumed caffeine amount was 185 mg per day. 194 (20%) students of the sample exceeded the recommended level of daily caffeine consumption (>400 mg/day). Among the measured demographics, only the year of study was associated with caffeine consumption (P value of .003), suggesting that students in their earlier years of university are likely to exceed the recommended daily consumption of caffeine in comparison with those who are in their later years of study. Our investigation identified high levels of caffeine consumption among some students. The findings imply the need to enhance the awareness of students who exceed the recommended daily intake of caffeine regarding the harmful impacts of caffeine toxicity.

Background and Objectives: The COVID-19 pandemic affects various populations worldwide. The discovery of vaccinations was necessary for the prevention and elimination of the disease. Despite the high importance of these vaccinations, they may cause some complications, such as ocular complications. This study aims to draw attention to the possible complications of the vaccination and highlight its importance. Materials and Methods: Systematic review of the literature from January 2021 to January 2023. A total of 20 published articles were included and reported cases of ocular complications in patients who received COVID-19 vaccines. Results: A total of 243 patients with verified ocular complications following the COVID-19 vaccination were included, ranging in age from 18 to 84 years. The most common ocular complications reported in the current study were ocular inflammatory complications, which represented 47.3%, followed by optic neuritis (24.3%). Retinal artery occlusion, retinal vein occlusion, acute macular neuroretinopathy, and paracentral acute middle maculopathy represented 10.7%. Herpetic ocular infections and herpetic eye disease (14%). Nearly half (42%) of the patients with ocular problems received the Pfizer-BioNTech vaccination. Conclusions: Despite the high importance of the COVID-19 vaccination, it was found that it is associated with the occurrence of some ocular complications. Future projects should come with more extensive prospective studies to further elucidate the underlying mechanisms and risk factors associated with ocular complications following COVID-19 vaccination, thereby enhancing our understanding and guiding appropriate management strategies.

Purpose: This study aims to assess contact lens usage patterns, complications, knowledge levels , the impact of psychological factors on misuse among the Saudi population. Methods: In this study, we distributed our questionnaire through multiple social media platforms among patients who are using cosmetic or medical contact lenses regardless of the purpose of wearing them. A total of 1,708 contact lens users participated. Results: Most participants were female (86.4%) , aged 21-40 years (65.7%). The purpose for usage was cosmetic (36.1%) or medical (28.7%), with some using them for both purposes (35.1%). Complications have been faced, with 26.3% experiencing issues due to lens usage, 56.8% facing visual problems, and 45.8% sometimes feeling discomfort with contact lens usage. Allergic reactions were reported by 35.2%. Higher knowledge levels were associated with participants aged 21-40 years (p = 0.009), irregular ophthalmologist visits (p = 0.032), and cosmetic use (p = 0.027). Better practice patterns were observed among urban residents (p = 0.049), higher-income earners (p = 0.002), cosmetic users (p < 0.001), and those with fewer complications (p < 0.001). Psychological factors significantly influenced misuse, with 15.4% of participants indicating its impact. Notably, a subset of these participants (16.2%) perceived prolonged wear of contact lenses as a manifestation of personal insecurity. Conclusions: Several sociodemographic factors, including place of residence, income, and difficulty, influence the use of contact lenses. It is also necessary to consider psychological issues such as low self- esteem and social acceptance while encouraging the safe use of contact lenses.

Background: Pediatric obstructive sleep apnea (OSA) is an under-recognized sleep-disordered breathing condition with important neurobehavioral and cardiometabolic consequences. This study assessed parental knowledge, attitudes, and practices (KAP) regarding pediatric OSA in southwestern Saudi Arabia and identified associated sociodemographic factors. Methods: An observational cross-sectional online survey was conducted in the Aseer and Jazan regions (June-August 2025). Parents (≥18 years) were recruited via social media using convenience sampling (N = 716). The validated Arabic questionnaire measured knowledge (0–11; adequate ≥6), attitudes (5–25; positive ≥16), and practices (0–12; adequate ≥7). Multivariable logistic regression examined predictors of adequate knowledge, positive attitudes, and adequate practice. Results: Inadequate knowledge was prevalent (66.3%), while most participants reported positive attitudes (82.3%). Among caregivers, reported practice was predominantly adequate (91.1%). In adjusted analyses, increasing age was associated with lower odds of adequate knowledge and positive attitudes (both aOR = 0.98 per year; p < 0.05). Female gender was associated with higher odds across KAP domains (aORs 1.47–1.58; p < 0.05). Higher education predicted better knowledge and more positive attitudes (p < 0.05), and a greater number of children predicted lower odds of adequate practice (aOR = 0.84; p = 0.036). Social media was the preferred awareness channel (49.5%), followed by school/community sessions (23.8%). Conclusion: Public knowledge of pediatric OSA in southwestern Saudi Arabia is limited despite positive attitudes, supporting targeted, culturally appropriate awareness interventions, primarily via social media.

Background and Clinical Significance: Ventriculoperitoneal (VP) shunting remains the standard definitive treatment for progressive neonatal obstructive hydrocephalus. Congenital chylous ascites is an uncommon neonatal condition, most often related to developmental lymphatic abnormalities. The concurrence of hydrocephalus requiring VP diversion with congenital chylous ascites is exceptionally rare and may first become apparent during abdominal access for shunt placement. Awareness of this possibility is clinically important because milky peritoneal fluid at shunt surgery can mimic gastrointestinal injury, and persistent postoperative abdominal fluid collections may be misattributed to shunt-related complications. Case Presentation: A late-preterm female infant (36 weeks’ gestation; birth weight 2.3 kg) presented with congenital hydrocephalus. Cranial ultrasonography was consistent with isolated aqueductal stenosis. Preoperative abdominal ultrasonography demonstrated mild ascites. On 27 May 2025, a VP shunt was placed for obstructive hydrocephalus. Upon entering the peritoneal cavity, milky-white fluid was encountered, prompting concern for bowel injury; however, careful exploration showed no gastrointestinal perforation. Ascitic fluid analysis revealed markedly elevated triglycerides (2300 mg/dL), confirming chylous ascites. The VP shunt was completed without an intraoperative complication. During follow-up, the infant showed appropriate growth (weight 3.0 kg; length 50 cm), while ascites persisted, and she was referred for multidisciplinary evaluation and management. Conclusions: This case highlights an exceptionally rare association of congenital chylous ascites with isolated aqueductal stenosis, identified incidentally during VP shunt insertion. Prompt intraoperative recognition, biochemical confirmation, and coordinated follow-up are essential to distinguish congenital chylous ascites from shunt-related abdominal fluid collections and to guide appropriate multidisciplinary care.