Implant-supported provisional restorations are critical for improving the esthetics and shaping of the peri-implant tissue. The mechanical properties of these provisional materials can be influenced by saliva, food, beverages, and interactions between these materials in the oral environment. Therefore, the integrity of provisional restorations should be preserved throughout the treatment period. This study aimed to evaluate the fracture strength of implant-supported polymethyl methacrylate (PMMA) provisional restorations made of computer-aided design and computer-aided manufacturing when immersed in different solutions at a controlled temperature of 37 °C for 7 days. Each analog-pillar-crown set was submerged in different liquids: 10 pieces were placed in distilled water then in tea, coffee, red wine, and Coca Cola^® for 1 week at a controlled oral temperature of 37 °C. The samples were then subjected to fracture forces. The moment of fracture of the crown was recorded and compared with those of the other samples. Specimens immersed in distilled water (control group) had the highest fracture resistance (mean [M] = 1331.00 ± 296.74 N), while those immersed in tea had the lowest mean resistance to fracture (mean [M] = 967.00 ± 281.86 N). Nutritional deficiency and inappropriate eating habits influence the fracture strength of temporary crowns, thereby rendering them more elastic or less resistant to fractures.