In this paper, a new socially assistive robot (SARs) called HBS-1.2 is presented, which uses 6-ply twisted and coiled polymer (TCP) artificial muscles in its hand to perform physical tasks. The utilization of 6-ply TCP artificial muscles in a humanoid robot hand is a pioneering advancement, offering cost effective, lightweight, and compact solution for SARs. The robot is designed to provide safer human–robot interaction (HRI) while performing physical tasks. The paper explains the procedures for fabrication and testing of the 6-ply TCP artificial muscles, along with improving the actuation response by using a Proportional-Integral-Derivative (PID) control method. Notably, the robot successfully performed a vision-based pick and place experiment, showing its potential for use in homecare and other settings to assist patients who suffer from neurological diseases like Alzheimer’s disease. The study also found an optimal light intensity range between 34 to 108 lumens/m², which ensures minimal variation in calculated distance with 95% confidence intervals for robust performance from the vison system. The findings of this study have important implications for the development of affordable and accessible robotic systems to support elderly patients with dementia, and future research should focus on further improving the use of TCP actuators in robotics.