In this work, the possibilities and benefits of using an ionic liquid as a potential dietary supplement are presented and discussed for the first time. Ionic liquids prevent the development of microorganisms due to high ion concentration and thus, prevent perishability of the food products. Thermal stability, structure, as well as the experimental density and viscosity in the temperature range from 20 to 50?C and at the atmospheric pressure 1x105 Pa of newly synthesized cholinium taurate ionic liquid, [Chol][Tau], are determined. According to the performed physicochemical characterization, it can be concluded that the synthesized ionic liquid is suitable for application in the food industry. The temperature variation of viscosity and density is discussed in terms of processes, packaging, and storage of [Chol][Tau]. Also, the antiproliferative activity of [Chol][Tau] is determined and compared with those obtained for ascorbic acid and Aspirin? as the standards.
Evolution of physicochemical parameters such as thermal stability, density, viscosity and electrical conductivity at various temperatures for two pharmaceutically active ionic liquids – tetracainium salicylate and tetracainium ibuprofenate.
Due to their appealing physiochemical properties, particularly in the pharmaceutical industry, deep eutectic solvents (DESs) and ionic liquids (ILs) are utilized in various research fields and industries. The presented research analyzes the thermodynamic properties of a deep eutectic solvent created from natural molecules, menthol and lauric acid in a 2:1 molar ratio, and an ionic liquid based on two active pharmaceutical ingredients, benzocainium ibuprofenate. Initially, the low solubility of benzocainium ibuprofenate in water was observed, and a hydrophobic natural deep eutectic mixture of menthol:lauric acid in a 2:1 ratio was prepared to improve benzocainium ibuprofenate solubility. In order to determine the solvent properties of DESs and ILs mixtures at different temperatures and their molecular interactions to enhance the solvent performance, the apparent molar volume, limiting apparent molar expansibility, and viscosity B coefficient were estimated in temperature range from 293.15 K to 313.15 K and varying concentration of benzocainium ibuprofenate.