The known metal-organic framework {Zn₄O(BDC)₃} (MOF-5 (I), where BDC is terephthalate anion) is synthesized by the solvothermal method in autoclaves prepared by 3D printing from polypropylene. The synthesized polymer is isolated in the individual state and characterized by elemental analysis and powder X-ray diffraction analysis. The crystal structures of MOF-5 and another coordination polymer based on zinc(II) terephthalate {Zn₄O(BDC)₃} · (ZnO)_0.125 (SUMOF-2 (II)) obtained as a by-product of the solvothermal synthesis are confirmed by X-ray diffraction analysis (СIF files ССDС nos. 1920366 (I) and 1926136 (II)).

Mono- and binuclear complexes [Cu(Fur)₂(Phen)] (I), [Cu₂(Fur)₄(Py)₂] (II), [Cu(Fur)₂-(Py)₂(H₂O)] (III), and [Zn₂(Fur)₄L₂] (L = Py (IV), Phpy (V)) are synthesized using the reactions of copper(II) and zinc(II) acetates with anions of pyromucic acid (2-furancarboxylic acid (HFur)) and N‑donor ligands (pyridine (Py), 4-phenylpyridine (Phpy), and 1,10-phenanthroline (Phen)) in acetonitrile. The copper complexes with pyridine are successively formed from the same reaction mixture: at first binuclear complex II is formed and then mononuclear complex III is formed. All compounds are isolated as single crystals, and their structures are determined by X-ray structure analysis (CIF files CCDC nos. 1974386 (I), 1974388 (II), 1974389 (III), 1974387 (IV), and 1974385 (V)). The thermal behavior of complexes II and III is studied by simultaneous thermal analysis. The biological activity in vitro of all complexes is determined toward the nonpathogenic mycobacterial strain Mycolicibacterium smegmatis. Complexes I and V exhibit a high biological activity and are promising for further studies of antitubercular activity.

The mononuclear complexes [M(Fur)₂(Bpy)(H₂O)] (M = Cu (I), Zn (II)) were prepared by the reactions of copper(II) and zinc(II) acetates with 2-furoic acid (HFur) anion and 2,2'-bipyridine (Bpy) in acetonitrile. A similar reaction with ZnCl₂ used instead of Zn(OAc)₂ · 2H₂O gave the complex [Zn(Fur)₂(Bpy)] (III). The cobalt(II) complex [Co(Fur)₂(Bpy)] (IV) was obtained by the reaction of cobalt trimethylacetate with HFur and Bpy. The structure of mononuclear complexes was determined by X-ray diffraction (CIF files CCDC nos. 1993168 (I), 1993169 (II), 1993170 (III), and 1993171 (IV)). Compounds I, III, and IV were studied for the biological activity in vitro against the nonpathogenic mycobacterial strain Mycolicibacterium smegmatis. It was found that I and III have high biological activity and are promising for further studies for antituberculosis activity.

Using the reactions of copper(II) acetate magnesium(II) oxide with 2-furancarboxylic acid (HFur), compounds with chemical compositions [Cu₂(Fur)₄(MeCN)₂] (I) and [Mg₂(Fur)₄(H₂O)₅]∙ MeCN∙H₂O (II) are synthesized. According to the X-ray diffraction data (CIF files CCDC nos. 2085817 (I) and 2085818 (II)), both complexes have a binuclear structure. The metal core of I correspond to the tetracarboxylate bridged {Cu₂(μ-Fur)₄} complex, the coordination number of the copper atom in which is 5 (CuNO₄); in II, the metal atoms are linked by two carboxylate groups and a water molecule, and the coordination environment of the metal centers is completed to the polyhedron (MgO₆) by oxygen atoms of the Fur^– anions and water molecules. According to EPR spectroscopy data, exchange-coupled copper(II) dimers with a substantial zero-field splitting are observed in I. For I and II, antibacterial activity against the nonpathogenic strain of M. smegmatis, and cytotoxicity against human ovarian adenocarcinoma cells SCOV3 and normal human fibroblast cells of the HDF line have been determined.