Depression and anxiety are among the most prevalent mental health conditions in Brazil. Both are associated with poor quality of life (HRQoL) and challenges in disease management for chronic illnesses, including Behçet's disease (BD). This study aimed to evaluate depression, anxiety, and HRQoL in BD patients from a non-endemic area. This case-control study included adult BD patients from Brazilian tertiary center and healthy controls (HC). All patients fulfilled the ISG and ICBD diagnostic criteria. Depression, anxiety and quality of life were assessed using BDI, HADS, SF-36, and physical capacity with the HAQ. We enrolled 58 BD patients (60% female, median age 48.5) and 96 HC (74% female, median age 40.5). High rates of depression and anxiety were observed in BD patients, correlating with disease activity, younger age, absence of a partner, shorter disease duration, and lower income. BD patients showed significant HRQoL restrictions, particularly in physical and emotional roles, compared to HC. Longer disease duration correlated with better HRQoL. High rates of depression and anxiety were observed in BD patients, negatively impacting HRQoL, particularly in those with higher disease activity. Further study and clinical attention are warranted to enhance patient care and outcomes.

Objective: Modifications in the severity and clinical expression of Behçet’s disease (BD) have been described in some areas that are considered endemic for the disease. This study aims to evaluate the chronological changes in epidemiology and clinical characteristics of BD patients in a referral center in Brazil, which is considered a non-endemic area for the disease. Methods: A descriptive and cross-sectional study involving BD patients divided into two groups: group 1 patients were diagnosed and followed between 1988 and 2010, and group 2 were diagnosed and followed between 2011 and 2022. Results: No significant differences were found regarding gender and age at onset of symptoms between groups. We found a significant decrease in the frequency of bilateral ocular involvement, posterior uveitis, and retinal vasculitis. Conclusion: The demographic dates of this group of Brazilian BD patients remained similar over the last decade. Our study supports the notion that BD is becoming lighter in some regions. BD is a severe blinding disorder, and we found a lower frequency of ocular involvement over time. These findings may be attributed to a higher level of education of patients and a growing awareness of the disease. Newer immunomodulating and biologic agents may offer an improved prognosis in patients with BD with severe manifestations.

Introdução: Neste trabalho iremos abordar um caso clinico sobre criptococose pulmonar. Será possível compreender que a patogênese da CP é uma infecção fúngica, vista como doença oportunista em pacientes imunodeprimidos sendo exclusivamente laboratorial seu diagnostico. Paciente JSF, de 75 anos de idade, sexo masculino, natural e procedente de Paraúna, Goiás, com queixa de febre e tosse há duas semanas com piora importante nos últimos 2 dias. Foi solicitado tomografia de tórax que suspeitou de quadro infeccioso fúngico, sendo solicitado exame para HIV que veio positivo, sendo então confirmado o diagnóstico de criptococose pulmonar em paciente imunossuprimido. A Criptococose Pulmonar pode ser facilmente confundida com outras patologias devido seu quadro inespecífico e diagnósticos diferenciais, sendo a confirmação com exame de escarro, lavado broncoalveolar, líquor ou fragmentos de tecido contendo obrigatoriamente uma das variantes do Cryptococcus neoformans  

Anais do SICASA e ANPPAS Amazônia (2178-3500) - Resíduos De Agrotóxicos Em Alimentos: Uma Análise Dos Resultados Do Programa Para De 2009 A 2012 Em Manaus/Am