Block compressive sensing (CS) is a well-known signal acquisition and reconstruction paradigm with widespread application prospects in science, engineering, and cybernetic systems. However, state-of-the-art block-based image CS (BCS) methods generally suffer from two issues. The sparsifying domain and the sensing matrices widely used for image acquisition are not data driven and, thus, both the features of the image and the relationships among subblock images are ignored. Moreover, it requires to address a high-dimensional optimization problem with extensive computational complexity for image reconstruction. In this article, we provide a deep learning (DL) strategy for BCS, called AutoBCS, which automatically takes the prior knowledge of images into account in the acquisition step and establishes a reconstruction model for performing fast image reconstruction. More precisely, we present a learning-based sensing matrix to accomplish image acquisition, thereby capturing and preserving more image characteristics than those captured by the existing methods. In addition, we build a noniterative reconstruction network, which provides an end-to-end BCS reconstruction framework to maximize image reconstruction efficiency. Furthermore, we investigate comprehensive comparison studies with both traditional BCS approaches and newly developed DL methods. Compared with these approaches, our proposed AutoBCS can not only provide superior performance in terms of image quality metrics (SSIM and PSNR) and visual perception but also automatically benefit reconstruction speed.

Quantitative susceptibility mapping (QSM) is an MRI post-processing technique that produces spatially resolved magnetic susceptibility maps from phase data. However, the traditional QSM reconstruction pipeline involves multiple non-trivial steps, including phase unwrapping, background field removal, and dipole inversion. These intermediate steps not only increase the reconstruction time but accumulates errors. This study aims to overcome existing limitations by developing a Laplacian-of-Trigonometric-functions (LoT) enhanced deep neural network for near-instant quantitative field and susceptibility mapping (i.e., iQFM and iQSM) from raw MRI phase data. The proposed iQFM and iQSM methods were compared with established reconstruction pipelines on simulated and in vivo datasets. In addition, experiments on patients with intracranial hemorrhage and multiple sclerosis were also performed to test the generalization of the proposed neural networks. The proposed iQFM and iQSM methods in healthy subjects yielded comparable results to those involving the intermediate steps while dramatically improving reconstruction accuracies on intracranial hemorrhages with large susceptibilities. High susceptibility contrast between multiple sclerosis lesions and healthy tissue was also achieved using the proposed methods. Comparative studies indicated that the most significant contributor to iQFM and iQSM over conventional multi-step methods was the elimination of traditional Laplacian unwrapping. The reconstruction time on the order of minutes for traditional approaches was shortened to around 0.1 s using the trained iQFM and iQSM neural networks.

Purpose: MRI is increasingly utilized for image‐guided radiotherapy due to its outstanding soft‐tissue contrast and lack of ionizing radiation. However, geometric distortions caused by gradient nonlinearities (GNLs) limit anatomical accuracy, potentially compromising the quality of tumor treatments. In addition, slow MR acquisition and reconstruction limit the potential for effective image guidance. Here, we demonstrate a deep learning‐based method that rapidly reconstructs distortion‐corrected images from raw k‐space data for MR‐guided radiotherapy applications.Methods: We leverage recent advances in interpretable unrolling networks to develop a Distortion‐Corrected Reconstruction Network (DCReconNet) that applies convolutional neural networks (CNNs) to learn effective regularizations and nonuniform fast Fourier transforms for GNL‐encoding. DCReconNet was trained on a public MR brain dataset from 11 healthy volunteers for fully sampled and accelerated techniques, including parallel imaging (PI) and compressed sensing (CS). The performance of DCReconNet was tested on phantom, brain, pelvis, and lung images acquired on a 1.0T MRI‐Linac. The DCReconNet, CS‐, PI‐and UNet‐based reconstructed image quality was measured by structural similarity (SSIM) and RMS error (RMSE) for numerical comparisons. The computation time and residual distortion for each method were also reported.Results: Imaging results demonstrated that DCReconNet better preserves image structures compared to CS‐ and PI‐based reconstruction methods. DCReconNet resulted in the highest SSIM (0.95 median value) and lowest RMSE (<0.04) on simulated brain images with four times acceleration. DCReconNet is over 10‐times faster than iterative, regularized reconstruction methods.Conclusions: DCReconNet provides fast and geometrically accurate image reconstruction and has the potential for MRI‐guided radiotherapy applications.

The Onderstepoort Journal of Veterinary Research (OJVR), is the official publication of the Onderstepoort Veterinary Institute. It publishes scientific papers reporting original research on diseases and disease vectors of livestock and wildlife with a focus on Africa, but with results of more than local interest.

The data-driven approach of supervised learning methods has limited applicability in solving dipole inversion in Quantitative Susceptibility Mapping (QSM) with varying scan parameters across different objects. To address this generalization issue in supervised QSM methods, we propose a novel training-free model-based unsupervised method called MoDIP (Model-based Deep Image Prior). MoDIP comprises a small, untrained network and a Data Fidelity Optimization (DFO) module. The network converges to an interim state, acting as an implicit prior for image regularization, while the optimization process enforces the physical model of QSM dipole inversion. Experimental results demonstrate MoDIP's excellent generalizability in solving QSM dipole inversion across different scan parameters. It exhibits robustness against pathological brain QSM, achieving over 32 % accuracy improvement than supervised deep learning methods. It is also 33 % more computationally efficient and runs 4 times faster than conventional DIP-based approaches, enabling 3D high-resolution image reconstruction in under 4.5 min.