Magdalena Molina-Barahona

Magdalena Molina-Barahona

orcid

Research Focus & Metrics

Academic Career Length

6Years (2021-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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23 May 2025 in Dentistry Journal
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Journal Article
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MMMagdalena Molina-Barahona
Magdalena Molina-Barahona
JCJordano Castillo
Jordano Castillo
EFEsteban Freire-Meza
Esteban Freire-Meza
AVAna Cristina Vásquez-Palacios
Ana Cristina Vásquez-Palacios
DMDenia Morales-Navarro
Denia Morales-Navarro
RARenata Avecillas-Rodas
Renata Avecillas-Rodas
Background: Tooth extractions commonly result in dimensional changes of the alveolar ridge. Platelet-rich fibrin (PRF) has emerged as a promising autologous biomaterial for alveolar preservation. This randomized controlled trial aimed to evaluate, through cone beam computed tomography (CBCT), the effect of PRF in maintaining alveolar dimensions post-extraction. Methods: A single-blind, randomized controlled clinical trial was conducted in 10 systemically healthy patients requiring premolar extractions for orthodontic reasons. A total of 36 alveoli were analyzed: 19 with PRF (experimental group) and 17 without PRF (control group). CBCT scans were performed at baseline, 30 days, and 120 days post-extraction to measure alveolar height, vestibulo-palatal/lingual depth at 1, 3, and 5 mm, and bone tissue density using Hounsfield Units (HU). Results: Baseline cephalocaudal alveolar height was similar in both groups (~10.5 mm, p = 0.399). At 30 days, height preservation was significantly greater in the PRF group (10.61 mm vs. 8.82 mm, p < 0.001). At 120 days, the PRF group maintained greater height (10.30 mm vs. 9.31 mm), although this difference was not statistically significant (p = 0.059). No significant differences were observed in alveolar depth at 1, 3, or 5 mm (p > 0.05). The PRF group showed a trend toward better preservation and higher mean bone density values (190–282 HU), although no formal statistical comparison of HU values was performed. Repeated measures ANOVA revealed a significant interaction effect of time and group on alveolar height (p = 0.010, η2 = 0.046) and at 1 mm depth (p = 0.035, η2 = 0.020). Conclusions: PRF significantly improved short-term alveolar height preservation. Trends toward better depth preservation and higher bone density values were observed in the PRF group, although these findings were not statistically significant. PRF appears to be a safe biomaterial with potential to support alveolar ridge maintenance post-extraction.

1 April 2025 in Preprints.org
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MMMagdalena Molina-Barahona
Magdalena Molina-Barahona
JCJordano Castillo
Jordano Castillo
EFEsteban Freire-Meza
Esteban Freire-Meza
AVAna Cristina Vásquez-Palacios
Ana Cristina Vásquez-Palacios
DMDenia Morales-Navarro
Denia Morales-Navarro
RARenata Avecillas-Rodas
Renata Avecillas-Rodas
There are many clinical reasons for tooth extraction due to caries, periodontal disease, trauma, infection or the need to gain space due to orthodontic treatment. This study aimed to radiographically evaluate the preservation of the dental alveolus using platelet-rich fibrin. A total of 17 alveoli without PRF and 19 alveoli with PRF were analyzed, with an initial cephalocaudal height of 10.5 mm in both groups. The dimensional changes of the crest were evaluated using cone beam computed tomography (CBCT) images acquired 30 and 120 days post-extraction. In the cephalocaudal height at 120 days, a difference of 0.99 mm was identified in the alveolar height of both groups. The group with PRF had a greater height reaching an average of 10.30 mm, regarding to the depth measured at 1 mm, 3 mm and 5 mm, no significant differences were identified between both groups at 30 and 120 days, however, it is highlighted that those alveoli with PRF presented a lower bone loss in depth (1,3,5 mm) of 8.06mm, 8.45mm and 9.04mm. PRF filling effectivily preserves the dimensions of the alveolar crest in height, depth and bone tissue quality following extraction.

29 November 2023 in Dentistry Journal
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Journal Article
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MMMagdalena Molina-Barahona
Magdalena Molina-Barahona
ADAndres Delgado-Gaete
Andres Delgado-Gaete
DMDenia Morales-Navarro
Denia Morales-Navarro
Joaquín Juan Urbizo-VélezJoaquín Juan Urbizo-Vélez
Joaquín Juan Urbizo-Vélez
RARenata Avecillas-Rodas
Renata Avecillas-Rodas
Tooth extraction is the most common procedure in dental practice. However, in the long term, it may cause alveolar ridge atrophy. This systematic review aimed to evaluate the role of platelet-rich fibrin (PRF) in post-exodontic alveolar ridge preservation in terms of its effectiveness in the regeneration of bone tissue as assessed by imaging and its efficacy compared to physiological bone healing. The study is presented in accordance with the preferred reporting items for systematic reviews and meta-analyses (PRISMA) guidelines. This systematic review was conducted using electronic databases such as PubMed, Scopus, Web of Science, and Science Direct. The gray literature search was conducted in the New York Academy of Medicine Grey Literature Report. All the studies in this systematic review were randomized controlled trials (RCTs). The risk of bias was performed according to the Cochrane Handbook for Systematic Reviews of Interventions 6.2 (RevMan 6.2). Considering the inclusion and exclusion criteria, we included 17 randomized clinical trials published up to 2022 investigating the efficacy of PRF in post-exodontic bone regeneration. Based on the results of clinical studies, it can be stated that despite not being statistically significant, PRF promotes neoformation and prevents bone loss between three and four months post-extraction.

30 June 2023 in Revista Científica Odontológica
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JMJorge Andrés Ochoa Moreira
Jorge Andrés Ochoa Moreira
SQSantiago José Reinoso Quezada
Santiago José Reinoso Quezada
MMMagdalena Molina-Barahona
Magdalena Molina-Barahona
The odontogenic keratocystic tumor (OKT) or also currently known as odontogenic keratocyst (OK) is a benign pathology derived from the remains of the dental lamina characteristic for possessing variable amounts of desquamated keratin. It usually rises as solitary or with the presence of satellite cysts, the appearance of these satellite cysts is frequently related to the possible recurrence of OK, according to the literature, this recurrence can vary between 0 - 50%. As for the treatment stage of (OKT), it can be mentioned that at present there is a well-defined histological and clinical criterion, which facilitates its recognition and therefore its treatment. According to the literature, there are several treatment procedures that can be classified into non-conservative or radical treatments and conservative treatments accompanied by adjuvant methods. Within the nonconservative or radical treatments, we find en bloc resection, which is the most aggressive way to treat a keratocyst; however, it is the most effective way to avoid recurrence. Within the conservative treatments, marsupialization, decompression, and enucleation with or without adjuvant therapy are described. It is paramount to know how to recognize the different types of treatment for (OKT) since this will be conditioned by multiple factors, such as the location of nearby bone structures and the size of the lesion considering the possible involvement of dental structures. The objective is to seek the lowest-risk treatment possible, which avoids recurrence and finally puts an end to this pathology.

29 December 2021
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UCUniversidad Católica de Cuenca
Universidad Católica de Cuenca
IOIvanna Cedillo Orellana
Ivanna Cedillo Orellana
MJMagaly Jiménez-Romero
Magaly Jiménez-Romero
MIMiriam Lima Illescas
Miriam Lima Illescas
MMMagdalena Molina-Barahona
Magdalena Molina-Barahona
La educación, como pilar fundamental de la sociedad, ha sufrido grandes cambios a raíz de la pandemia ocasionada por el SARS-CoV-2 que provocó la enfermedad de COVID–19, generándose confinamientos que limitaron la práctica estomatológica. Es por ello que, mediante el despliegue de modalidades en el aprendizaje virtual, a través de la utilización de diversas plataformas, con el apoyo de autoridades, docentes y estudiantes, la carrera de Odontología de la Universidad Católica de Cuenca, en coordinación con el Centro de Educación Continua y la Jefatura de Vinculación con la Sociedad, organizaron eventos como el VII Congreso Internacional de Especialidades Odontológicas e Investigación: Vinculación con la Sociedad, para incrementar las oportunidades de aprendizaje, innovando la educación en modalidad virtual. El resultado del congreso se traduce en este libro, en el cual el lector encontrará temas actuales y relevantes de la odontología que incluyen conocimientos acerca de promoción, prevención, diagnóstico, tratamiento en niños y adultos, calidad de vida, investigación, tecnología aplicada a la odontología así como nuevos enfoques, relacionados con las especialidades de endodoncia, cirugía, ortodoncia, odontopediatría, rehabilitación oral, salud pública, periodoncia, imagenología, estética dental, entre otros. El confinamiento no fue un obstáculo para el intercambio de conocimientos desde y hacia diversas partes del mundo, es así que este libro de memorias plasma teorías, conceptos, investigaciones y casos clínicos llevados a cabo por profesionales en diferentes áreas odontológicas. Dada la importancia de difundir la valiosa información compartida por los expositores, se desarrolló la edición de esta obra que fue realizada con gran esfuerzo y esmero para contribuir con la formación de los profesionales del campo de la odontología.

13 June 2025 in Anatomía Digital
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MMMagdalena Molina-Barahona
Magdalena Molina-Barahona
GSGabriela Verónica Rosales Salcedo
Gabriela Verónica Rosales Salcedo
CEChristian Silva Erráez
Christian Silva Erráez
DNDenia Morales Navarro
Denia Morales Navarro
Introducción. La extracción dental por enfermedad pulpar, periapical y periodontal es uno de los procedimientos más comunes en odontología, siendo impredecible la cicatrización y pérdida de volumen que provoca atrofia de la cresta ósea alveolar a largo plazo. Utilizando una evaluación clínica y de imagen de publicaciones de investigación de Ensayos Clínicos Controlados Aleatorios (ECA) recientes, el Objetivo es analizar la aplicación de la fibrina rica en plaquetas en la regeneración ósea de los alvéolos dentales posexodoncia. Metodología de acuerdo con el protocolo (PRISMA 2020), este estudio es un documental cualitativo, transversal y descriptivo. En este estudio sistemático se emplearon bases de datos electrónicas como PubMed, Scielo, Google académico, Embase y Redalyc. EL riesgo de sesgo se realizó según el Manual de Cochrane para Revisiones Sistemáticas de Intervenciones 6.2 (RevMan 6.2), con criterios de inclusión y exclusión, incluyendo 25 ensayos clínicos aleatorizados publicados hasta el 2022, que hayan investigado el uso de PRF en la regeneración ósea y de tejidos blandos en sitios de exodoncia. Resultados la presente revisión sistemática de acuerdo con los hallazgos heterogéneos de la investigación clínica, Conclusiones el PRF es útil para preservar el reborde alveolar posexodoncia, la estabilidad dimensional vertical e impulsar la proliferación de células lo cual previene la disminución de la cresta ósea alveolar vestibular, lingual o palatina, cabe mencionar que otros no han encontrado diferencias significativas debido a variaciones en diseño o metodología por lo que se requiere investigaciones adicionales estandarizadas prolongadas. Área de estudio general: odontología Área de estudio específica: cirugía oral Tipo de estudio: Revisión bibliográfica sistemática.