Archana Muralidharan

Dr. Archana Muralidharan

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Research Focus & Metrics

Academic Career Length

4Years (2023-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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12 September 2023 in Diagnostics
Verified
Journal Article
Open access
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JAJunaid Ahmed
Junaid Ahmed
AGAditya Gupta
Aditya Gupta
NSNandita Shenoy
Nandita Shenoy
NSNanditha Sujir
Nanditha Sujir
AMArchana Muralidharan
Archana Muralidharan
CBCT significantly impacts dental procedures and has brought significant reforms to our approach to diagnosis and treatment planning despite its limitations in differentiating soft tissues. It is an excellent imaging modality and quickly identifies sinus opacification and provides valuable insight into paranasal sinus pathologies, with considerably lower radiation exposure. The present study aimed to investigate the occurrence of maxillary sinus abnormalities in CBCT scans, identify the frequency, type, and location of these findings, and find the correlation between the distance of periapical lesions and radiographic changes in the maxillary sinus. Two examiners independently evaluated 117 patients to diagnose and classify the cases into different abnormality subtypes. The periapical lesions most closely related to the sinus were recorded. The diameters of the left and right maxillary sinus ostium and the distance of the ostium’s lower border to the sinus’s osseous floor were recorded. The findings were correlated with the age and gender of these patients. The present study reveals that sixty-one patients were diagnosed with mucosal thickening (52.1%). The sinus wall most affected by mucosal thickening was the maxillary sinus floor, followed by the medial and lateral walls. Of 19 patients with periapical lesions, 15 had maxillary sinus mucosal thickening, which is statistically significant (p = 0.004). The high occurrence of abnormalities in the maxillary sinus emphasizes the importance for the radiologist to comprehensively interpret the whole volume acquired in CBCT images, including the entire sinus. Incidental findings may be considered in the individual clinical context of signs and symptoms, reducing the risk of overestimating the real impact of radiographic findings.

18 June 2024 in Journal of Oral Biology and Craniofacial Research
Verified
Journal Article
Open access
JAJunaid Ahmed
Junaid Ahmed
NANamrata
Namrata
NSNanditha Sujir
Nanditha Sujir
NSNandita Shenoy
Nandita Shenoy
SNSrikant Natarajan
Srikant Natarajan
ASAshwin C Shetty
Ashwin C Shetty
This study aimed to evaluate linear measurements of the frontal sinus (FS) and sphenoid sinus (SS) for sex identification on cone beam computed tomography (CBCT) images. A comparative CBCT analysis was conducted on 200 full field of view (FOV) scans taken as part of routine dental investigations. Dimensions of the bilateral frontal and sphenoid sinuses were measured. Intra- and interobserver reliability were calculated. Independent t tests were used to compare the various parameters between sexes. Stepwise discriminant function analysis was used to determine sex. Additionally, the receiver operating characteristic (ROC) curve, area under the curve (AUC), sensitivity, and specificity were also determined. A p value < 0.05 was considered significant. A total of 200 CBCT scans were included in the study. The mean age (±SD) among males was 25.66 (±7.11) and that among females was 24.64 (±5.12). The ROC curve revealed that the right length of the frontal sinus showed the greatest accuracy in sex identification in comparison to other linear measurements of the FS and SS. The results of our study indicated that the equation obtained from stepwise discriminant function analysis can aid in sex determination with an accuracy of 76.5 %. Our findings support the sexual dimorphism of linear measurements of FS and SS. There was an improvement in the accuracy of sex prediction when the linear measurements of FS and SS were considered in combination rather than in isolation. The derived equation can be an adjunctive tool for sex identification for the representative population.

1 January 2025 in Journal of Periodontal & Implant Science
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Journal Article
Open access
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UYUtkarsh Yadav
Utkarsh Yadav
NSNandita Shenoy
Nandita Shenoy
JAJunaid Ahmed
Junaid Ahmed
NSNanditha Sujir
Nanditha Sujir
AMArchana Muralidharan
Archana Muralidharan
AGAarti Gupta
Aarti Gupta
Yadav U, et al. J Periodontal Implant Sci. 2024 Jul;54:e20. https://doi.org/10.5051/jpis.2401300065

1 January 2024 in The Scientific World Journal
Verified
Journal Article
Open access
JAJunaid Ahmed
Junaid Ahmed
NANamrata
Namrata
NSNanditha Sujir
Nanditha Sujir
NSNandita Shenoy
Nandita Shenoy
AMArchana Muralidharan
Archana Muralidharan
SNSrikant Natarajan
Srikant Natarajan
Background. This study aims to evaluate the accuracy rate of foramen magnum dimensions in determining sex among the South Indian population using discriminant functional analysis. Methods. An observational study in which CBCT images from 200 full field of view (FOV) scans were analysed. The dimensions of the foramen magnum were measured. Intra‐ and interobserver reliability were calculated. Independent t‐tests were used to compare the various parameters between sexes. Stepwise discriminant function analysis was used to determine sex. Results. A total of 200 CBCT scans were included in the study. The mean age (±SD) was 25.66 (±7.11) years among males and 24.64 (±5.12) years among females. The measurements and the circumference of the foramen magnum were significantly (p < 0.001) greater in males than in females. The univariate analysis of foramen magnum measurements reached an accuracy rate of 73.5% in sex determination. The discriminant function analysis combining the foramen magnum measurements and circumference yielded an overall predictability rate of 66.5% for determining sex. Conclusion. Taking into account the predictability rate of sex based on foramen measurement in the present population, it can be concluded that its applicability should be limited to cases associated with fragmentary skull bases.

25 March 2024 in Oral Radiology
Verified
Journal Article
Closed access
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ATArjun Kumar Tallada
Arjun Kumar Tallada
JAJunaid Ahmed
Junaid Ahmed
NSNanditha Sujir
Nanditha Sujir
NSNandita Shenoy
Nandita Shenoy
SPShubham M. Pawar
Shubham M. Pawar
SMSanjay Mallya
Sanjay Mallya

1 June 2023 in Acta Marisiensis - Seria Medica
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Journal Article
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JSJayachandran Sadaksharam
Jayachandran Sadaksharam
SPSophia Jeba Priya
Sophia Jeba Priya
SSSripriya Subramaniam
Sripriya Subramaniam
AMArchana Muralidharan
Archana Muralidharan
The term amyloidosis refers to a wide range of diseases in which amorphous, extracellular, eosinophilic proteinaceous deposits form at various locations. In this article, we describe a case of amyloidosis with multiple myeloma in which the oral symptoms of the disease served as the main diagnostic clues. A male patient in his early 60s who had multiple tongue swellings presented to our department. Following an incisional biopsy, histological analysis revealed the presence of eosinophilic, amorphous hyaline-like material that was positive for Congo red staining and was indicative of amyloidosis. The presence of abnormal plasma cells in the patient’s bone marrow aspiration after the biopsy was done was suggestive of multiple myeloma. The patient is currently undergoing the CyBorD (Cyclophosphamide, Bortezomib, and Dexamethasone) treatment for multiple myeloma that has just been diagnosed. We offer this instance to demonstrate that, although uncommon, amyloidosis can initially only manifest as numerous swellings on the tongue.