Non-destructive testing (NDT) techniques play an important role in the characterization and diagnosis of historic buildings, keeping in mind their conservation and possible rehabilitation. This paper presents a new approach that merges building information modeling (BIM) with environment geospatial data obtained by several non-destructive techniques, namely terrestrial laser scanning, ground-penetrating radar, infrared thermography, and the automatic classification of pathologies based on RGB (red, green, blue) imaging acquired with an unmanned aircraft system (UAS). This approach was applied to the inspection of the Monastery of Batalha in Leiria, Portugal, a UNESCO World Heritage Site. To assess the capabilities of each technique, different parts of the monastery were examined, namely (i) part of its west façade, including a few protruding buttresses, and (ii) the masonry vaults of the Church (nave, right-hand aisle, and transept) and the Founder’s Chapel. After describing the employed techniques, a discussion of the optimization, treatment and integration of the acquired data through the BIM approach is presented. This work intends to contribute to the application of BIM in the field of cultural heritage, aiming at its future use in different activities such as facility management, support in the restoration and rehabilitation process, and research.