Advanced medical materials and manufacturing technologies are highly in demand in artificial bones. Herein, a four-arm star-shaped polycaprolactone polyurethane acrylate (FPCLA) was designed and synthesized. The photosensitive character of FPCLA contributed to the rapid prototyping and personalized customization under digital light processing (DLP) 3D printing technology. The FPCLA was prepared by introducing unsaturated double bonds into polycaprolactone tetraethyl alcohol (PCLT). We characterized the physico-chemical properties of the material through FTIR, H-NMR, GPC, DSC and SEM. Cell behaviors on material were observed in vitro. In addition, we employed a DLP 3D printer to evaluate the feasibility of FPCLA to fabricate artificial bone model. The photocuring star polycaprolactone was confirmed in detail by detection method. SEM analyses demonstrated that FPCLA has good tenacity. The material can be used to fabricated artificial bone with a diameter of 3.02 mm at its narrowest by DLP 3D printing technology. The cell survival rates of CCK-8 and Live/Dead fluorescence staining experiments were both above 90%, which indicated safety and feasibility of such new-generation artificial bone made of synthetic polymers.

Background: Coarctation of the aorta (CoA) with a non-restrictive ventricular septal defect (VSD) is a severe congenital heart defect. Traditional single-stage repair often requires deep hypothermic circulatory arrest (DHCA), increasing surgical risk in neonates. Case summary: A 1-day-old male neonate with prenatal diagnosis of CoA and VSD presented with respiratory distress. Imaging confirmed CoA with arch hypoplasia and a large VSD. He underwent a modified single-stage repair via median sternotomy. The innovative approach involved initial aortic arch reconstruction without cardiopulmonary bypass (CPB), followed by VSD closure under mild hypothermic CPB. The chest was closed primarily. Recovery was remarkable: ventilator support 23 h, intensive care unit stay 4 days, and total hospitalization 13 days. Discharge echocardiogram showed excellent cardiac function with no complications. Discussion: This modified single-stage approach successfully treated CoA with VSD while avoiding DHCA. The technique’s key advantage lies in performing arch reconstruction without CPB first, significantly reducing CPB duration and eliminating neurological risks associated with DHCA. The excellent postoperative recovery demonstrates this strategy’s potential benefits over conventional methods, offering a promising surgical alternative for managing this complex condition in infants.