Nashiru Billa

Prof. Nashiru Billa

College of Pharmacy, QU Health, Qatar University, Doha 2713, Qatar
orcid

Research Focus & Metrics

Academic Career Length

30Years (1997-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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10 January 2019 in AAPS PharmSciTech
Verified
Journal Article
Closed access
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RNRajesh Sreedharan Nair
Rajesh Sreedharan Nair
AMAndrew Morris
Andrew Morris
Nashiru BillaNashiru Billa
Nashiru Billa
CLChee-Onn Leong
Chee-Onn Leong

1 January 2017 in Journal of Controlled Release
Verified
Journal Article
Closed access
MWMing Ming Wen
Ming Ming Wen
NENoha S. El-Salamouni
Noha S. El-Salamouni
WEWessam M. El-Refaie
Wessam M. El-Refaie
HHHeba A. Hazzah
Heba A. Hazzah
MAMai M. Ali
Mai M. Ali
Amira HanafyAmira Hanafy
Amira Hanafy

1 March 2012 in Ultrasonics Sonochemistry
Verified
Journal Article
Open access
Patrick Tang Siah YingPatrick Tang Siah Ying
Patrick Tang Siah Ying
SMSIVAKUMAR MANICKAM
SIVAKUMAR MANICKAM
TWTan Khang Wei
Tan Khang Wei
Nashiru BillaNashiru Billa
Nashiru Billa
In the present study, response surface methodology (RSM) based on central composite design (CCD) was employed to investigate the influence of main emulsion composition variables, namely drug loading, oil content, emulsifier content as well as the effect of the ultrasonic operating parameters such as pre-mixing time, ultrasonic amplitude, and irradiation time on the properties of aspirin-loaded nanoemulsions. The two main emulsion properties studied as response variables were: mean droplet size and polydispersity index. The ultimate goal of the present work was to determine the optimum level of the six independent variables in which an optimal aspirin nanoemulsion with desirable properties could be produced. The response surface analysis results clearly showed that the variability of two responses could be depicted as a linear function of the content of main emulsion compositions and ultrasonic processing variables. In the present investigation, it is evidently shown that ultrasound cavitation is a powerful yet promising approach in the controlled production of aspirin nanoemulsions with smaller average droplet size in a range of 200-300 nm and with a polydispersity index (PDI) of about 0.30. This study proved that the use of low frequency ultrasound is of considerable importance in the controlled production of pharmaceutical nanoemulsions in the drug delivery system.

1 April 2014 in Colloids and Surfaces B: Biointerfaces
Verified
Journal Article
Closed access
LCLay Hong Chuah
Lay Hong Chuah
CRClive J Roberts
Clive J Roberts
Nashiru BillaNashiru Billa
Nashiru Billa
SASyahril Abdullah
Syahril Abdullah
RRRozita Rosli
Rozita Rosli

10 December 2011 in Pharmaceutical Development and Technology
Verified
Journal Article
Closed access
LCLay Hong Chuah
Lay Hong Chuah
Nashiru BillaNashiru Billa
Nashiru Billa
CRClive J Roberts
Clive J Roberts
Jonathan C. BurleyJonathan C. Burley
Jonathan C. Burley
SMSIVAKUMAR MANICKAM
SIVAKUMAR MANICKAM
In the present study, we investigate the mucoadhesive characteristics and release of the anticancer agent curcumin, contained in chitosan nanoparticles (CS-NPs). Such a system has potential therapeutic benefits in the treatment of colon cancer through prolonged retention and delivery. The CS-NPs were ionically gelled with tripolyphosphate (TPP) and registered an isoelectric pH of 6.2 (z-average diameter of 214 nm ± 1.0 nm). pH variations around the isoelectric point caused a reduction in CS-NPs electrical charge which correspondingly increased the z-average due to agglomeration. Curcumin release from CS-NPs was slowest at chitosan to TPP weight ratio of 3:1, with a significant retention (36%) at the end of 6 h. Adsorption isotherms of mucin on CS-NPs fitted both the Freundlich and Langmuir models, suggesting a monolayer-limited adsorption on heterogeneous sites with varied affinities. Encapsulated curcumin exerted an influence on the adsorption of mucin due to H-bonding as well as π-π interactions between the phenolic moieties of curcumin and mucin.

1 December 2010 in Colloids and Surfaces A: Physicochemical and Engineering Aspects
Verified
Journal Article
Closed access
STS.W. Tan
S.W. Tan
Nashiru BillaNashiru Billa
Nashiru Billa
CRClive J Roberts
Clive J Roberts
Jonathan C. BurleyJonathan C. Burley
Jonathan C. Burley