Three-dimensional (3D) bioprinting has emerged as a revolutionary approach in the life sciences, combining multiple disciplines such as computer engineering, materials science, robotics, and biomedical engineering. This innovative technology enables the production of cellular constructs using bio-inks, and differs from conventional 3D printing by incorporating living cells. The present work addresses the conversion of a commercial thermoplastic 3D printer into a low-cost bioprinter. The modification addresses the challenges of the high cost of commercial bioprinters, limited adaptability, and specialized personnel requirements. This modification uses an extrusion-based bioprinting method that is particularly popular in research due to its viscosity tolerance and versatility. The individual steps, including replacing the extruder with a syringe pump, rebuilding the electronic motherboard, and configuring the firmware, are explained in detail. The work aims at providing access to bioprinting technology so that laboratories with modest resources can take advantage of the immense potential of this technology. This modification resulted in improved resolution, allowing submicron movements, which is comparable to some of the commercially available bioprinters. The accuracy of the modified printer was validated using hydrogel bioprinting tests, suggesting that it is suitable for broader applications in regenerative medicine.
In recent years, the transportation industry has faced the challenge of cutting costs, meeting increasingly stringent environmental regulations, and significantly increasing transportation volumes. One approach to meeting these challenges is to develop new, improved transportation vehicles using new materials and innovative joining techniques. Multi-material structures are becoming an alternative to body parts. Self-pierce riveting technology plays a crucial role in this process, and hybrid structures depend exclusively on it. In this article, recent advances in self-pierce riveting technology are analyzed to meet today’s challenges and future multi-material applications.
1 June 2024 in Advances in Science and Technology Research Journal
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