Introduction: Atopic dermatitis (AD) is associated with various systemic diseases. However, its association with diabetes mellitus (DM) was discussed controversially. Few researchers reviewed the association of these two common morbid disorders. This meta-analysis aimed to assess the relationship between AD and DM. Methods: We systematically searched PubMed including Epub and ahead of print (198 articles identified) and Cochrane (13 articles) databases. The searching engine was set to include case-control, prospective and retrospective cohorts, and cross-sectional studies from the first published up to February 12, 2021. Two hundred and eleven were identified, eighteen full texts were screened; of them, six were included in the final meta-analysis. The keywords used were AD, diabetes mellitus, type 1 diabetes, and type 2 diabetes. A datasheet was used to record the author's name, year of publication, country and type of the studies, number of events, and total number in the two arms (patients and controls). Results: Out of the 211 references identified, six studies were pooled to test the association between diabetes mellitus and AD. The studies showed that AD is lower among patients with DM, odds ratio, 0.69, 95% CI, and 0.67-0.72. No heterogeneity was observed (Chi-Square, 4.12, degree of freedom (df.)= 5, and I² = 0%, P-value), 0.53 and P-value for overall effect, <0.001. The included studies were published in Europe (five) and Canada (one study) and included 162,882 patients and 12,164 events, four of the studied articles were case-control studies, one retrospective, and one cross-sectional. Conclusion: AD was lower among patients with DM compared to their counterparts without the disease. Further studies focusing on the genetic and environmental factors linking AD and diabetes are needed.

The increasing prevalence of antibiotic resistance, driven by the production of extended-spectrum beta-lactamases (ESBLs), presents a critical challenge to current medical treatments, particularly in clinical settings. Understanding the distribution and frequency of ESBL-producing bacteria is essential for developing effective control strategies. This study investigated the antibiotic resistance and extended-spectrum beta-lactamase (ESBL) production in bacterial isolates in clinical and non-clinical (food) specimens in Tabuk, KSA. A total of 57 bacterial isolates were analysed, with E. coli and Pseudomonas sp. being the most prevalent. High resistance rates were observed, particularly against third-generation cephalosporins in clinical isolates. ESBL screening revealed a significant prevalence in clinical samples (58.3%), with E. coli showing the highest positivity. Conversely, only a low percentage of food isolates were ESBL positive. Molecular analysis confirmed the presence of various ESBL genes, with bla_CTX-M being the most frequent, predominantly found in clinical isolates. This study highlights the concerning levels of antibiotic resistance and ESBL production in the region, emphasising the need for effective infection control measures and prudent antibiotic use.

The incidence of cancer increased substantially in the previous decades. In addition, increasing mortality was observed. No researchers have assessed cancer prevalence in Tabuk, Saudi Arabia. The current study investigated the pattern of cancer in Tabuk City, Saudi Arabia. A retrospective hospital-based study was conducted in the Pathology Department at King Fahd Specialist Hospital from June 2023 to September 2023. All the records of patients diagnosed with malignancies between 2019 and 2020 we

Background: Laparoscopic (LCS) and robotic-assisted colorectal surgery (RACS) are commonly utilized minimally invasive procedures for colorectal cancer (CRC). However, their comparative effectiveness remains debated. This systematic review and meta-analysis examined short-term outcomes between LCS and RACS to support clinical decision-making. Methods: A systematic search of PubMed, Cochrane Library, Science Direct, and Web of Science was performed following Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) principles. Fifteen studies (n=15) comparing LCS and RACS in CRC patients were included. Primary outcomes were operation time and hospital length of stay (LOS). Secondary outcomes post-operative complications. Data were pooled using random-effects models, with heterogeneity measured via I² statistics. Results: Concerning operative Time, RACS required considerably longer operations than LCS (SMD: -0.68, 95% CI: -1.09 to -0.28; I²=92.6%). RACS revealed a small but substantial reduction in LOS (SMD: 0.3, 95% CI: 0.11–0.48; I²=96%). LCS had fewer overall complications (RR: 0.78, 95% CI: 0.62–0.97), including decreased anastomotic leak (RR: 0.80) and readmission rates (RR: 0.87). RACS was consistently more expensive, with 50% greater costs in some studies. Conclusions: LCS is the standard minimally invasive method due to its shorter surgical times, lower costs, and comparable—or superior—safety profile. RACS may assist specific patients (e.g., difficult pelvic dissections) but lacks wide advantages to support frequent use. Further randomized trials are needed to identify their ideal role.