Marta Guadalupi

Dr. Marta Guadalupi

orcid

Research Focus & Metrics

Academic Career Length

5Years (2022-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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8 December 2023 in Veterinary Sciences
Verified
Journal Article
Open access
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MGMarta Guadalupi
Marta Guadalupi
ACAlberto Crovace
Alberto Crovace
DMDonato Monopoli
Donato Monopoli
Francesco  StaffieriFrancesco Staffieri
Francesco Staffieri
LLLuca Lacitignola
Luca Lacitignola
The aim of this study was to objectively evaluate lameness in dogs affected by a unilateral cranial cruciate ligament rupture (CrCLR) treated with porous tibial tuberosity advancement before surgery and at three different timepoints after surgery, using the GAITRite® system (version 4.9Wr), a pressure-sensitive walkway system that is able to calculate several spatiotemporal gait parameters simultaneously for each limb. The dogs walked on the pressure-sensitive walkway before (T0) and 30 (T1), 90 (T2), and 120 (T3) days after surgery. Pressure measurements (gait lameness score and total pressure index %) were collected for S (treated with porous TTA) and C (healthy contralateral limb) at T0, T1, T2, and T3 and statistically evaluated. An ANOVA test was performed to compare the data, and a value of p < 0.05 was considered significant. Twenty dogs (n = 20) of various common breeds and ages with CrCLR were enrolled in the study. The results showed that there was a statistically significant difference in the GAIT4Dog® lameness score (GLS) and TPI% between S and C for each timepoint. Statistically significant differences in the GLS and TPI% between S at T0 and S at T2 and between S at T0 and S at T3 (p < 0.001) were found. The results showed that there was a statistically significant difference in the GAIT4Dog® lameness score (GLS) and TPI% between S and C for each timepoint. Statistically significant differences in the GLS and TPI% between S at T0 and S at T2 and between S at T0 and S at T3 were found. The GLS and TPI% increased statistically significantly from 90 days after surgery compared to the preoperative measurements. Moreover, comparing the GLS and TPI% between the treated limb and the control limb showed that a statistically significant difference remained at each timepoint.

10 March 2022 in Animals
Verified
Journal Article
Open access
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LLLuca Lacitignola
Luca Lacitignola
PLPietro Laricchiuta
Pietro Laricchiuta
AIAnnarita Imperante
Annarita Imperante
CAClaudia Acquafredda
Claudia Acquafredda
Marzia StabileMarzia Stabile
Marzia Stabile
Francesco  StaffieriFrancesco Staffieri
Francesco Staffieri
The aim of this study was to assess the feasibility and intraoperative complications of performing ovariectomies in African lionesses (Panthera leo) using a wound retractor laparoscopic platform. Six lionesses (n = 6) were included. The surgical procedures were carried out through three portals, with a retractor platform positioned at the umbilical port and cannulas placed 3–4 cm from the cranial and caudal regions to the device at the level of the midline. An ovariectomy was performed with a vessel-sealing device. We evaluated the surgery time and the intraoperative and early postoperative complications. The mean weight was 172.83 kg. The total surgery time was 49.33 min. The installation step took a mean of 10.33 min to complete. The mean ovariectomy time was 20 min. Controlled bleeding was observed at the tip of the uterine horn in two cases due to excessive tissue thickness. The retrieval of dissected ovarian tissue and annexes was easily performed. No other complications were observed. The use of the laparoscopic platform during three-portal surgeries for laparoscopic ovariectomy in adult overweight lionesses is feasible and without intraoperative problems. The retractor meant that there were no entry-related issues due to the 25 mm mini-laparotomy. It also made it simpler to extract thick ovaries and promptly re-establish the pneumoperitoneum.

6 September 2022 in Animals
Verified
Journal Article
Open access
PDF file
LLLuca Lacitignola
Luca Lacitignola
PLPietro Laricchiuta
Pietro Laricchiuta
MGMarta Guadalupi
Marta Guadalupi
Marzia StabileMarzia Stabile
Marzia Stabile
ASAnnalaura Scardia
Annalaura Scardia
Francesco  StaffieriFrancesco Staffieri
Francesco Staffieri
To evaluate two vessel-sealing devices with different jaw lengths for dissecting ovaries in adult obese African lionesses undergoing laparoscopic ovariectomy. Twelve lionesses (n = 12) were recruited. The surgical procedures were performed through three portals, with a retractor platform positioned at the umbilical port and cannulas placed 3–4 cm cranial and caudal to the device at the level of the midline. Ovariectomy was performed using a vessel-sealing device according to a randomization list. We evaluated the surgery time the intra- and postoperative complications. The total surgery time was 49.3 min (range 40–61 min) in the Atlas group and significantly lower in the Caiman group (mean 31.8 min, range 26–51 min). The installation phase was similar between the groups. The ovariectomy time was significantly lower in the Caiman group (mean 7.8 min, range 4–11 min) than in the Atlas group (mean 20 min, range 16–30 min). Controlled bleeding was observed at the tip of the uterine horn in two cases in the Atlas group. No other complications were noted. The results of our study confirmed the significant advantages of employing the Caiman 12 vessel-sealing device in comparison with the LigaSure Atlas in terms of the time needed to complete ovariectomy, although both instruments could be considered safe. The use of the Caiman 12 is recommended when performing laparoscopic ovariectomies in adults with obesity.

6 August 2024 in Veterinary Sciences
Verified
Journal Article
Open access
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MGMarta Guadalupi
Marta Guadalupi
CPClaudia Piemontese
Claudia Piemontese
Marzia StabileMarzia Stabile
Marzia Stabile
RDRosanna Dizonno
Rosanna Dizonno
Francesco  StaffieriFrancesco Staffieri
Francesco Staffieri
LLLuca Lacitignola
Luca Lacitignola
The use of minimally invasive methods has grown in popularity due to decreased postoperative morbidity and a quicker recovery. Colopexy is a surgical method that includes the permanent adhesion of the colonic seromuscular layer to the abdominal wall to avoid rectal prolapses in cats and dogs with viable prolapsed tissues. In this case series, we describe the treatment of three cats with total laparoscopic colopexy (TLC) for recurrent rectal prolapses. A non-incisional colopexy was created by suturing the colon to the abdominal wall with a barbed suture. There were no intraoperative complications and a 6-month follow-up revealed no prolapse recurrence. Our study demonstrates that TLC approaches are feasible, safe, and free of problems when used to treat recurrent rectal prolapses in cats, although a larger caseload is required to validate the results obtained from our reported cases.

18 March 2026 in Veterinary Sciences
Verified
Journal Article
Open access
PDF file
ACAlberto Crovace
Alberto Crovace
MGMarta Guadalupi
Marta Guadalupi
RBRoberta Belvito
Roberta Belvito
CMChiara Monopoli
Chiara Monopoli
AAAlejandro Artiles
Alejandro Artiles
ACANTONIO CROVACE
ANTONIO CROVACE
Radial and ulnar fractures in toy-breed dogs are associated with a high risk of complications due to limited bone stock and soft tissue coverage. The aim of this retrospective study was to evaluate the postoperative clinical and radiographic outcomes in dogs undergoing radial and ulnar fracture stabilization with a titanium locking mini-plate system. Medical records and radiographs of toy-breed dogs weighing ≤5 kg treated between 2020 and 2025 were reviewed. Twenty-six dogs met the inclusion criteria. Radiographic union after primary fixation was observed in 92.9% of fractures. Implant failure occurred in 7.1% of cases and was successfully addressed with revision surgery, after which fracture healing was achieved. At final follow-up, limb function was graded as excellent in all dogs, including those requiring revision surgery. A shorter distal fragment length was significantly associated with implant failure, whereas implant length and proximal fragment length showed no significant association. These findings indicate that titanium locking mini-plates were associated with favorable clinical and radiographic outcomes. Distal fragment dimensions may influence the risk of implant failure and should be considered during surgical planning. However, the small number of implant failure events limits the robustness of statistical inferences, and the absence of a control group prevents direct comparison with alternative fixation techniques.

12 January 2026 in Veterinary Research Communications
Verified
Journal Article
Open access
PDF file
MGMarta Guadalupi
Marta Guadalupi
CPClaudia Piemontese
Claudia Piemontese
Marzia StabileMarzia Stabile
Marzia Stabile
CVCaterina Vicenti
Caterina Vicenti
ACAlberto Crovace
Alberto Crovace
LLLuca Lacitignola
Luca Lacitignola
Summary: To compare surgical time, incision length, intraoperative bleeding, and post-operative pain in cats undergoing three different ovariectomy techniques: open surgery with pedicle ligation using sutures, open surgery using a bipolar vessel-sealing device, and a two-port laparoscopic approach. A prospective randomized clinical trial was conducted on 27 healthy female cats assigned to three treatment groups ( n = 9 per group). Surgical variables were recorded intraoperatively, and post-operative pain was assessed using a validated feline pain scale at hourly intervals over four hours. The laparoscopic group had the shortest incision length (mean 10.0 mm, SD 0.0) compared to the suture (mean 33.3 mm, SD 5.6) and bipolar device groups (mean 28.7 mm, SD 6.4). Surgical time was significantly shorter in the BVSD (27.0 ± 9.6 min) and LOVE groups (30.2 ± 5.2 min) compared with the Suture group (43.9 ± 14.4 min; one-way ANOVA, p = 0.005; Tukey post-hoc p < 0.05 vs. Suture for both comparisons). Post-operative pain scores at one hour (T1) were lower in the LOVE group (median 4 [IQR 3–5]) than in both open groups (Suture: 9 [IQR 8–9]; BVSD: 7 [IQR 6–8]; Kruskal–Wallis, p = 0.014; Dunn’s post-hoc p < 0.05 vs. BVSD and trend towards lower scores vs. Suture). Only 1 of 9 cats requiring rescue analgesia versus 7 of 9 in each open group. The laparoscopic approach was associated with lower post-operative pain scores and a reduced need for rescue analgesia compared to open ovariectomy techniques, suggesting improved perioperative comfort. Although the laparoscopic group showed a significantly shorter surgical time compared with the suture group, this observation should be interpreted cautiously due to potential operator- and case-dependent variability. Nevertheless, laparoscopic ovariectomy in cats should be considered a promising and welfare-oriented technique that warrants further investigation.