Francesco Pirato

Dr. Francesco Pirato

orcid

Research Focus & Metrics

Academic Career Length

6Years (2021-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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14 March 2024 in Journal of Orthopaedics
Verified
Journal Article
Open access
GCGiorgio Cacciola
Giorgio Cacciola
FGFortunato Giustra
Fortunato Giustra
Francesco BoscoFrancesco Bosco
Francesco Bosco
DVDaniele Vezza
Daniele Vezza
FPFrancesco Pirato
Francesco Pirato
LSLuigi Sabatini
Luigi Sabatini
Total knee arthroplasty (TKA) is a common surgical procedure for end-stage knee osteoarthritis. However, conventional alignment techniques may lead to postoperative dissatisfaction in up to 20% of cases. Kinematic alignment (KA) has emerged as a new philosophy to restore the native joint line and achieve more natural kinematics. Preserving the posterior tibial slope (PTS) and posterior cruciate ligament (PCL) is crucial to maintaining the pre-arthritic joint line and improving knee kinematics. This study aimed to assess the prevalence of postoperative PTS changes and their impact on functional outcomes and range of motion. A retrospective single-center study was conducted on patients who underwent KA-TKA with PCL preservation. The preoperative and postoperative PTS were measured on lateral knee radiographs using the tibial proximal anatomic axis method. Patient-reported outcome measures (PROMs) were collected pre- and postoperatively up to a two-year follow-up. Of the 95 included patients, 62.1% achieved an anatomically similar PTS (within 3° from the preoperative value), while 37.9% experienced noticeable PTS changes. However, no significant associations existed between PTS changes and compromised PROMs (WOMAC, 22.2 and 23.1; FJS, 66.6 and 67.3), ROM (118.5° and 119.4°), or patient satisfaction. No postoperative complications requiring reoperation or component revisions were observed. Preserving or modifying the native PTS during KA-TKA could be confidently undertaken without compromising functional outcomes or patient satisfaction.

3 May 2025 in Medicina
Verified
Journal Article
Open access
PDF file
FRFrancesco Romano
Francesco Romano
RRRoberto Rossi
Roberto Rossi
UCUmberto Cottino
Umberto Cottino
MBMatteo Bruzzone
Matteo Bruzzone
FPFrancesco Pirato
Francesco Pirato
FRFederica Rosso
Federica Rosso
Background and Objectives: Total knee arthroplasty (TKA) is one of the most common medical procedures worldwide. However, 10 to 20% of patients are still dissatisfied despite implants and surgical technique advancements. Recently, several medial-stabilized TKAs have been developed in attempts to replicate the native kinematics of the knee. The aim of this scoping review on medial-stabilized TKA inserts—medial congruent (MC) and medial pivot (MP)—is to focus on their clinical outcomes and the role of the posterior cruciate ligament (PCL), aiming to systematically map the existing research and highlight current knowledge gaps. Materials and Methods: A search of the PubMed, Embase and Cochrane databases was performed to identify relevant studies on the kinematics and outcomes of medial pivot (MP) or medial congruent (MC) inserts. The following Mesh terms were used in combination with the Boolean operators “AND” and “OR”: “total knee arthroplasty”, “total knee replacement”, “medial pivot”, “medial congruence”, “outcomes” and “kinematic”. Original studies reporting on clinical outcomes assessed with validated patient-reported scales, surgical techniques and reoperation rates for any reason with a minimum follow-up of 18 months were included. Results: A total of 39 articles met the inclusion criteria, accounting for 6143 total knee replacements. The overall reoperation-free survivorship rate was 98.4% (6047 out of 6143 knees) at a weighted average follow-up of 6.3 years (range 1.5–15.2 years, SD 0.7). Both MP and MC inserts demonstrated good outcomes, with no differences between groups. Few studies evaluated the role of the PCL in MP and MC inserts, with no differences in terms of clinical outcomes between retaining and sacrificing the PCL. Conclusions: MS-TKA demonstrated good outcomes in the literature independently of the specific design (medial pivot or medial congruent). Different possible biases may be present when evaluating the outcomes of these inserts, including different types of alignment and soft tissue balancing philosophies.

5 July 2021 in Archives of orthopaedic and trauma surgery
Verified
Journal Article
Closed access
PDF file
JLJoel Locher
Joel Locher
Umile Giuseppe LongoUmile Giuseppe Longo
Umile Giuseppe Longo
FPFrancesco Pirato
Francesco Pirato
RSRoman Susdorf
Roman Susdorf
HHHeath B. Henninger
Heath B. Henninger
TSThomas Suter
Thomas Suter

1 May 2024 in EFORT Open Reviews
Verified
Journal Article
Open access
PDF file
FPFrancesco Pirato
Francesco Pirato
FRFederica Rosso
Federica Rosso
FDFederico Dettoni
Federico Dettoni
DBDavide Edoardo Bonasia
Davide Edoardo Bonasia
MBMatteo Bruzzone
Matteo Bruzzone
RRRoberto Rossi
Roberto Rossi
Knee stiffness is a widely known and worrying condition in several postoperative knees. Less is known about native stiff knee. The aim of this manuscript is to summarize the available literature on native stiff knee epidemiology, classification and treatment. In 1989 stiff knee was defined as a knee with less than 50° of total range of motion. If range of motion is <30°, it is defined as an ankylosed knee. Knee stiffness can be divided into three main types: flexion contractures, extension contractures, and combined contractures. Different risk factors have been associated to native stiff knee and grouped into modifiable or not modifiable. Furthermore, risk factors can be divided into patients’ related no patients’-related. Different treatment modalities can be indicated to treat knee stiffness, including manipulation under anesthesia (MUA), arthroscopic and open surgical release. When stiffness is associated with articular disruption TKA represent an option. TKA in native stiff knee can be challenging for the surgeon. Implant’s choice and knee exposure are the first steps. In some cases, additional release and extensive can be considered. A stepwise approach and careful preoperative planning are mandatory to obtain long-term satisfactory outcomes. Native stiff knee is a rare but invalidating condition. Different treatment modalities have been proposed as treatment. However, considering that it is frequently associated to sever arthritis, TKA can be an option in painful stiff knees. Nature of knee stiffness necessitates a customized approach to ensure successful management and achieve satisfying outcomes.

16 December 2024 in Prosthesis
Verified
Journal Article
Open access
PDF file
FPFrancesco Pirato
Francesco Pirato
JVJacopo Vittori
Jacopo Vittori
FDFederico Dettoni
Federico Dettoni
MBMatteo Bruzzone
Matteo Bruzzone
RRRoberto Rossi
Roberto Rossi
UCUmberto Cottino
Umberto Cottino
Background: Complications such as periprosthetic fractures necessitate challenging revision surgeries. In particular, femoral stem revisions can be complicated by poor bone quality, making primary stability and leg length restoration difficult to achieve. Modular fluted tapered stems (MFTSs) have emerged as a viable option for these complex cases. This study aims to describe a reproducible three-step technique for femoral stem revision using MFTSs. The technique focuses on (1) obtaining distal primary stability, (2) restoring leg length, and (3) ensuring overall implant stability. Materials and methods: We conducted a retrospective analysis of ten patients who underwent revision THA using this three-step technique, with a minimum follow-up of 12 months. The mean patient age was 70.7 years, and the average follow-up was 24.2 months. Limits were the small sample size, the lack of clinical outcomes and the short-term follow-up. Results: There was no subsidence, a mean leg length discrepancy of 4 mm (p: 0.604), and no dislocations. However, heterotopic ossifications (HOs) were observed in 25% of patients, although no trochanteric migrations occurred. One patient experienced an intraoperative femoral fracture, which was successfully treated. Conclusions: This three-step approach can break down the revision procedure, making it more accessible to surgeons. The findings suggest that this technique is effective in achieving reliable outcomes in femoral stem revisions, potentially improving the standard of care for patients requiring complex THA revisions.