Maurizio Bruno

Prof. Maurizio Bruno

Department of Biological, Chemical and Pharmaceutical Sciences and Technologies, University of Palermo, Palermo, Italy
orcid

Research Focus & Metrics

Academic Career Length

46Years (1981-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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27 February 2009 in Molecules
Verified
Journal Article
Open access
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Adriana BasileAdriana Basile
Adriana Basile
SSSergio Sorbo
Sergio Sorbo
VSVivienne Spadaro
Vivienne Spadaro
Maurizio BrunoMaurizio Bruno
Maurizio Bruno
Antonella MaggioAntonella Maggio
Antonella Maggio
SRSergio Rosselli
Sergio Rosselli
We report the isolation of several coumarins and the stereochemical assessment of some pyranocoumarins, as well as the antibacterial and antioxidant activities of the three most abundant ones (grandivittin, agasyllin and aegelinol benzoate) isolated from the roots of Ferulago campestris collected in Sicily and of the hydrolysis product (aegelinol). Aegelinol and agasyllin showed antibacterial activity against nine ATCC and the same clinically isolated Gram-positive and Gram-negative bacterial strains. At a concentration between 16 and 125 mg/mL both coumarins showed a significant antibacterial effect against both Gram-negative and Gram-positive bacteria. In particular the ATCC strains Staphylococcus aureus, Salmonella thypii, Enterobacter cloacae and Enterobacter earogenes (MIC = 16 and 32 mg/mL for aegelinol and agasyllin, respectively) were the most inhibited. Antibacterial activity was also found against Helicobacter pylori: a dose-dependent inhibition was shown between 5 and 25 mg/mL. The antioxidant activity of the coumarins was evaluated by their effects on human whole blood leukocytes (WB) and on isolated polymorphonucleate (PMN) chemiluminescence (CL), PMA-stimulated and resting.

1 May 2013 in Food and Chemical Toxicology
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Journal Article
Closed access
ARAlessandra Russo
Alessandra Russo
CFCarmen Formisano
Carmen Formisano
Daniela RiganoDaniela Rigano
Daniela Rigano
FSFelice Senatore
Felice Senatore
SDSebastiano Delfine
Sebastiano Delfine
Maurizio BrunoMaurizio Bruno
Maurizio Bruno

7 February 2020 in Molecules
Verified
Journal Article
Open access
PDF file
FPFranco Palla
Franco Palla
Maurizio BrunoMaurizio Bruno
Maurizio Bruno
FMFederica Mercurio
Federica Mercurio
ATAntonella Tantillo
Antonella Tantillo
VRValentina Rotolo
Valentina Rotolo
Essential oils (EOs) have been known for a long time, and they are used in several fields such as medicine and aromatherapy, as well as in the food and pharmaceutical industries. In the last decade, EOs have also been applied to contrast the biodeterioration of cultural heritage, representing a powerful resource in green conservation strategies. In this study, an integrated approach based on microscopic observation, in vitro culture, and molecular investigation was preliminarily employed to identify biological systems colonizing wooden artworks. In order to contrast the biodeterioration processes induced by fungal colonization (Aspergillus flavus) or insect infestation (Anobium punctatum), wooden artworks were exposed to the volatile compound of Origanum vulgare or Thymus vulgaris essential oils (EOs), the chemical composition of which was determined by GC–MS using both polar and apolar columns. Artwork exposure was performed in ad-hoc-assembled “clean chambers.” Evaluating the effects on biological systems, the compatibility with artwork constitutive materials, and the lack of negative effects on human health and environmental pollution, the use of EOs as a valid alternative to traditional biocides must be considered.

1 December 2017 in Industrial Crops and Products
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Journal Article
Closed access
Roman PavelaRoman Pavela
Roman Pavela
Filippo MaggiFilippo Maggi
Filippo Maggi
GLGiulio Lupidi
Giulio Lupidi
Kevin CianfaglioneKevin Cianfaglione
Kevin Cianfaglione
XDXavier Dauvergne
Xavier Dauvergne
GBGiovanni Benelli
Giovanni Benelli

1 May 2018 in Corrosion Science
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Journal Article
Closed access
MCMaria Pia Casaletto
Maria Pia Casaletto
VFViviana Figà
Viviana Figà
Antonella PriviteraAntonella Privitera
Antonella Privitera
Maurizio BrunoMaurizio Bruno
Maurizio Bruno
ANAssunta Napolitano
Assunta Napolitano
SPSonia Piacente
Sonia Piacente

1 January 1989 in Tetrahedron
Verified
Journal Article
Closed access
DBDearg S. Brown
Dearg S. Brown
Maurizio BrunoMaurizio Bruno
Maurizio Bruno
RDRaymond J. Davenport
Raymond J. Davenport
SLSteven V. Ley
Steven V. Ley