Florian Schmidt

Dr. Florian Schmidt


Research Focus & Metrics

Academic Career Length

4Years (2023-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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4 May 2024 in European Archives of Oto-Rhino-Laryngology
Verified
Journal Article
Closed access
PDF file
FSFlorian Schmidt
Florian Schmidt
ADAlexander Dörmann
Alexander Dörmann
KEKarsten Ehrt
Karsten Ehrt
WGWilma Grossmann
Wilma Grossmann
RMRobert Mlynski
Robert Mlynski
LZLichun Zhang
Lichun Zhang

16 January 2024 in Journal of Clinical Medicine
Verified
Journal Article
Open access
PDF file
FSFlorian Schmidt
Florian Schmidt
THThomas Hocke
Thomas Hocke
LZLichun Zhang
Lichun Zhang
WGWilma Großmann
Wilma Großmann
RMRobert Mlynski
Robert Mlynski
Among hearing aid (HA) users, there is a considerable variability in word recognition scores (WRSs). This variability is most pronounced among individuals with moderately severe to severe hearing loss. The variability cannot be adequately explained by factors such as pure-tone audiogram, audiogram type or age. This prospective study was designed to investigate the relationship between tone decay (TD) and WRS in a group of HA users with corresponding pure-tone hearing loss. The study population included 22 patients with hearing loss between 50 and 80 dB HL. Aided WRS, unaided WRS and TD were assessed for both ears. TD was found to be frequency-dependent. TD and WRS were correlated, with up to R = −0.66. The TD test was revealed to be a feasible method for explaining variability in WRS among HA users with hearing loss below 80 dB. This may contribute to improved differential diagnostics. The TD test may thus offer a better understanding of the limitations of HA use in the context of cochlear implant candidacy assessment for HA users.

16 April 2025 in Audiology Research
Verified
Journal Article
Open access
PDF file
LZLichun Zhang
Lichun Zhang
DMDavid Mißler
David Mißler
KEKarsten Ehrt
Karsten Ehrt
WGWilma Großmann
Wilma Großmann
RMRobert Mlynski
Robert Mlynski
FSFlorian Schmidt
Florian Schmidt
Background/Objectives: In the early stage of presbycusis, patients experience reduced speech perception in noisy environments despite normal audiometry, normally known as hidden hearing loss. Diagnostic indicators like the reduced amplitude of ABR wave I, elevated extended high-frequency threshold (EHT), and decreased middle ear muscle reflex (MEMR) amplitude aim to identify biomarkers of peripheral auditory pathology but remain inconsistent. Mismatch negativity (MMN) is a cortical auditory evoked potential generated when the brain detects sound changes. This study aimed to assess MMN as a diagnostic tool for hidden hearing loss in adults. Methods: Seventy-three subjects with normal hearing underwent an extended pure-tone audiogram examination ranging from 0.125 to 16 kHz and a subsequent MMN assessment with two different paradigms: a speech (ba/da) and a tone (1/2 kHz) paradigm. The MMN’s amplitude and latency were measured and analyzed. Results: The outcome shows a significant age-related effect on MMN amplitude in the speech condition (χ² = 13.0, p = 0.002). Specifically, the MMN amplitude in the 25–30-year-old group was significantly smaller than in the 20–25-year-old group (p = 0.0015, Cohen’s d = 0.63). Additionally, no further effects of age were observed on the cortical potentials examined. Also, neither tone nor speech paradigms showed a significant influence of EHT on the amplitude or latency of either MMN or P300. Conclusions: The application of MMN as an electrophysiological tool to diagnose hidden hearing loss in normal hearing adults has limitations. However, in contrast to MMN responses to tonal stimuli, the present study reveals that MMN amplitude obtained with speech stimuli may indicate early signs of central auditory deficits.

13 December 2023 in Preprints.org
Verified
Preprint
Open access
PDF file
FSFlorian Schmidt
Florian Schmidt
THThomas Hocke
Thomas Hocke
LZLichun Zhang
Lichun Zhang
WGWilma Großmann
Wilma Großmann
RMRobert Mlynski
Robert Mlynski
Among hearing aid (HA) users, there is a considerable variability in word-recognition scores (WRS). This variability is most pronounced among individuals with moderately severe to severe hearing loss. The variability cannot be adequately explained by factors such as the pure-tone audiogram, audiogram type, or age. This prospective study was designed to investigate the relationship between tone decay (TD) and WRS in a group of HA users with corresponding pure-tone hearing loss. The study population included 22 patients with hearing loss between 50 and 80 dB HL. Aided WRS, unaided WRS and TD were assessed for both ears. TD was found to be frequency-dependent. TD and WRS were correlated, with up to R=–0.66. The TD test was revealed as a feasible method for explaining the variability in WRS among HA users with hearing loss below 80 dB. This may contribute to improved differential diagnostics. The TD test may thus offer a better understanding of the limitations of HA use in the context of cochlear implant candidacy assessment for HA users.

28 August 2026 in Otology & Neurotology
Verified
Journal Article
Closed access
FSFlorian Schmidt
Florian Schmidt
TSTammo Siemers
Tammo Siemers
DCDaniel Cantré
Daniel Cantré
KEKarsten Ehrt
Karsten Ehrt
WGWilma Großmann
Wilma Großmann
LZLichun Zhang
Lichun Zhang
Objective: To apply a semiautomatic method for quantifying cochlear nerve cross-sectional area (CSA) based on 3D models from MRI picture and to evaluate the association between CSA at different nerve locations and postoperative speech perception in cochlear implant (CI) users. Study design: Retrospective cohort study. Setting: University Medical Center, tertiary academic referral center. Patients: Twenty adult patients with asymmetric hearing loss undergoing a MED-EL cochlear implant (Synchrony 2, FLEX electrode series; MED-EL, Innsbruck, Austria) between 2020 and 2024. Intervention: Preoperative MRI images were used for manual segmentation for the cochlear nerve (CN) and facial nerve (FN) followed by 3D reconstruction. CSA of the CN (ACN) and FN (AFN) was automatically quantified along the entire nerve course. Postoperative speech perception was assessed using word recognition scores (WRS) at the first fitting. Main outcome measures: Semiautomatic CSA measurements showed excellent agreement with manual measurements (R ANC =0.95±0.06). CSA near the cochlear aperture exhibited the strongest correlation with postoperative speech perception. Peak correlation for polysyllabic tests at approximately 10% of the normalized nerve length (R max =0.74) and for monosyllabic tests at approximately 24% (R max =0.56). Conclusion: This study establishes a reliable semiautomatic method for cochlear nerve CSA quantification and identifies the nerve region near the cochlear aperture as a promising imaging biomarker for predicting postoperative speech outcomes in CI patients