Corn peptides (CPs) are a novel food prepared from corn gluten meal, which is a main by-product of the corn starch industry. Recently, significant beneficial effects of CPs on early alcoholic liver injury in rats and on acute alcoholic injury in mice were observed. To our knowledge, the present study is the first report showing that CPs supplementation has beneficial effects on lipid profile, oxidative stress and alcoholic liver injury in men with chronic alcohol consumption. A 9-week, randomized, double-blind, placebo-controlled study was conducted between September 2011 and August 2012 to assess the hepatoprotective effect of CPs. A total of 161 men were randomized to receive CPs (n = 53), whey protein (n = 54), or corn starch placebo (n = 54) at the same dose of 2 g twice daily. 146 participants completed the study. Serum lipid profile, serum markers of liver injury, oxidative stress and inflammation, and fatty liver based on the results of abdominal ultrasonography were assessed at the beginning and end of the intervention. CPs supplementation (4 g/d) for 9 weeks significantly lowered serum levels or activities of total cholesterol, triglyceride, alanine aminotransferase, aspartate aminotransferase, malondialdehyde and tumor necrosis factor-α, and significantly increased serum activities of superoxide dismutase and glutathione peroxidase, but the same dose of whey protein and corn starch (placebo) did not demonstrate these effects. Our results indicate that CPs may have protective effects on alcohol-induced liver damage via modulation of lipid metabolism and oxidative stress. CPs may potentially be used as a functional food for the management of alcoholic liver disease in subjects with chronic alcohol consumption.

Sarcopenia represents a constant threat to the health of older adults, and accurate risk perception is essential for disease prevention and control. However, current methodologies lack rigorously validated instruments to assess the perceived risk of sarcopenia among this group. Thus, this study aimed to develop and validate a sarcopenia disease risk perception scale for older adults. The study was conducted in two phases: development of the initial scale and its psychometric evaluation. A STROBE checklist was employed. Based on the two-factor model of risk perception theory and the health belief model, the initial draft of the scale was created through literature review, expert consultations, and a preliminary survey with a small sample. Then, we used a cross-sectional study methodology to conveniently select 438 Chinese older adults. Item analysis, exploratory factor analysis (EFA), and confirmatory factor analysis (CFA) were used to refine and validate the scale items. Internal consistency and external consistency were assessed to confirm the scale’s reliability. These evaluations established the scale’s framework: content validity, item analysis, and EFA. The two factors extracted from the initial analysis explained 62.250% of the observation variance. The CFA confirmed a good fit for the model, demonstrating the scale’s robust reliability and validity. The finalized scale includes 15 items and two dimensions: perceived susceptibility (eight items) and perceived severity (seven items). The Sarcopenia Disease Risk Perception Scale for Older Adults is reliable and valid, making it appropriate for assessing the risk perception level in the target population.

This study aims to systematically review the illness experience of adolescent patients with type 1 diabetes mellitus (T1DM). The JBI qualitative systematic review method was used and meta-aggregate analysis of 14 qualitative studies was performed. Qualitative studies on the disease experience of adolescent patients with T1DM were obtained from Cochrane, PubMed, Web of Science, CINAHL, Embase, Wanfang, CNKI, and VIP, and the search period was from 1995 to 2024. The qualitative research quality evaluation tool of JBI the Evidence-based Health Care Center in Australia was used to evaluate the analysis results. Thirty-one results were distilled and categorized into 7 themes and then synthesized into 3 overarching findings: (1) experiencing psychological distress and developing coping mechanisms following adjustment; (2) acknowledging self-management shortcomings and actively seeking support; and (3) overcoming challenges and growing through experiences. The findings illuminate that adolescents with T1DM often experience negative physical and emotional challenges during their illness. Transitioning from dependency to independence poses numerous obstacles that can be overcome by improving both internal and external support, cultivating self-management skills, strengthening coping mechanisms, and achieving control over the disease while fostering personal growth. (c) 2024 Korean Society of Nursing Science. Published by Elsevier BV. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

Background: Nutrition literacy is essential for the self-management and treatment of gout patients. However, to date, there is no appropriate scale to measure the level of nutrition literacy gout patients in China. Objective: This study objective to develop and psychometric nutrition literacy scale for patients with gout. Methods: Using item development and psychological assessment. First, literature review, brainstorming, delphi study, and pr-survey were used to construct draft of the nutrition literacy scale for patients with gout. Second, 526 patients with gout underwent scale-based surveys. Item analysis and exploratory factors were used to optimize the scale. Confirmatory factor analysis was used to verify the structure of the scale, including the goodness of fit of the model, convergent validity, and discriminant validity. Subsequently, the reliability of the scale was tested using cronbach’s α coefficient and test-retest reliability. Results: The formal scale contains 5 dimensions: nutrition belief, nutrition knowledge, nutrition information acquisition ability, nutrition information interaction ability, nutrition information criticism ability, and 26 items. The overall content validity of the scale is 0.933. Exploratory factor analysis extracted 5 factors with a cumulative variance contribution of 82.18%. Confirmatory factor analysis showed that the scale structure was well fitted, with good convergent and discriminant validity. The overall cronbach’s α coefficient of this scale was 0.873, and the cronbach’s α coefficients of the dimensions were 0.861 ~ 0.980, and the overall re-test reliability was 0.864, and the re-test reliabilities of the dimensions were 0.881 ~ 0.981. Conclusion: Nutrition Literacy Scale for Gout Patients has good reliability and validity. It is suitable for the evaluation of nutrition literacy level in relevant population.

Purpose: To systematically evaluate the life experience of adolescents after kidney transplantation. Methods: We use computer search Web of Science, PubMed, Cochrane Library, Embase, EBSCO, CNKI, Wanfang, VIP database, search database to October 2024, screening after kidney transplant adolescents life experience of qualitative study. We used the Australian Joanna Briggs Institute Critical Appraisal Checklist for Qualitative Research to quality evaluation, and using the thematic analysis method to integrate the results. Results: 7 articles were included, and 31 research results were integrated into 8 new categories and combined results are 3 integration results: complex emotional experience; eager for multifaceted support; self-adjustment. Conclusion: Nursing staff should pay attention to the psychological experience and needs of adolescents, to eliminate their stigma, to promote positive cognition, and to improve their quality of life.

Background: Nutrition literacy is an important predictor of eating behavior in patients with type 2 diabetes. However, current methods lack rigorously validated tools to assess nutrient literacy in this group. Therefore, the aim of this study was to develop and validate the Nutrition Literacy Scale for patients with type 2 diabetes mellitus.Methods: This study was divided into two phases, including the generation of the items and the validation of the scales. The generation of the items was developed through a literature study, semi-structured interviews, a Delphi expert consultation, and a small-sample pre-survey. Convenience sampling method was used to select a large sample of 576 patients in Hangzhou for item analysis, reliability and validity tests.Results: The formal scale covered 4 dimensions with 31 items. The exploratory factor analysis extracted four common factors with a cumulative variance contribution of 62.725%; the results of the confirmatory factor analysis showed that the model fit was good, the content validity of the scale was 0.957. The calibration correlation validity of the newly developed scale with the Adult Nutrition Literacy Measurement Scale was 0.760. Cronbach’s α coefficient was 0.946, and re-test reliabilitiy was 0.884.Conclusion: The nutrition literacy scale for people with type 2 diabetes has good reliability and validity and is suitable for assessing the level of nutrition literacy in relevant populations.