PURPOSE We aimed to evaluate BIRADS-3 breast lesions with dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) and compare with histopathology, and to investigate the effectiveness of breast MRI for follow-up and management. METHODS A total of 84 BIRADS-3 lesions reported by US at mammography and evaluated by DCE-MRI between September 2014 and October 2015 were included in this study. All patients underwent percutaneous or surgical biopsy for histopathologic diagnosis. Morphologic and kinematic features on MRI were compared with histopathologic results. RESULTS Of the 84 BIRADS-3 breast lesions, 9 (10.7%) had malignant features on DCE-MRI and all were verified with histopathologic results. DCE-MRI had 96.7% sensitivity, 72% specificity, 92% positive predictive value, arid 82.5% negative predictive value. MRI arid histopathology results were correlated for the diagnosis of malignant lesions. The sensitivity arid negative predictive value of MRI for diagnosis of malignant lesions were both 100%. CONCLUSION Differentiation of benign versus malignant lesions was accomplished with 100% accuracy with DCE-MRI. We suggest that DCE-MRI should be an additional diagnostic tool and problem-solving modality for BIRADS-3 lesions, particularly in patients with relative risk factors.

Background: Tunneled catheters are effectively used in patients receiving chronic dialysis due to end-stage renal disease. However, the dysfunction of catheters caused by infection or thrombus requires repetitive procedures. In this study, we aimed to compare the long-term results of heparin-coated and non-heparin-coated tunneled dialysis catheters. Method: The study included a total of 161 patients who underwent tunneled dialysis catheter placement. Heparin-coated and non-heparin-coated tunneled catheters were placed in 81 and 80 patients, respectively. Of all the patients, 89 (55.3%) were male and 72 (44.7%) were female. The mean age of the patients was 64.3 ± 15.3 years. The patients were followed up for 12 months. Results: Catheter infection developed in 10 (6.2%) of the cases, of which seven (70%) resolved with antibiotic therapy and the remaining three (30%) required catheter replacement. There was no significant difference between the groups in terms of the catheter infection rate ( p = 0.84). Fibrin sheaths developed in nine (5.5%) patients. Fibrin sheath development was found to be significantly higher in the non-heparin-coated catheters ( p = 0.017). There was no significant difference in fibrin sheath formation between the patients with and without systemic antiaggregant use ( p = 0.864). The mean catheter durability time was determined to be 11 months in both groups ( p = 0.704). Catheter survival was similar in heparin-coated and non-heparin coated catheters. Conclusion: This study showed that the rate of fibrin sheath development was significantly lower in heparin-coated tunneled catheters than non-heparin-coated catheters. There was no significant difference between the two catheters in terms of the rates of infection and mechanical complications.